Endocrine Abstracts

Background: To minimize potential harm from overtreatment of low-risk thyroid cancers, the 2015 American Thyroid Association (ATA) Guidelines recommend that radioactive iodine (RAI) ablation should not be routinely used in low-risk differentiated thyroid carcinoma (DTC). The present study aims to evaluate trends in RAI therapy in a tertiary center after the update of these Guidelines.Methods: Data from patients followed in a tertiary center with low-risk...

Introduction: Graves orbitopathy is the major extrathyroidal manifestation of Graves Disease (GD). The approach depends on its clinical activity and severity. Treatment and referral to specialized centers, with Endocrinology and Ophthalmology, has a strong impact on the prognosis of Graves’ Disease (GD) and GO.Cases report: We report four cases of DG with OG. Their characteristics and clinical evolution are shown in Table 1.<table boarder="1" ce...

Background: Adrenal insufficiency (AI) is can be often under recognised condition in the clinical practise which can potentially result in adrenal crisis or even death if not treated properly. Identification of patients who are at risk of developing AI is important in order to take appropriate steps in minimising unwanted incidents. Objectives: Study aims to assess whether we identify patients who are at risk of AI and take recommended precautions.<p...

Introduction: Mitochondrial diabetes represents about 1% of diabetes but still very often misunderstood. The most frequent mutation is 3243A >G of the mtDNA, which is responsible for the maternally inherited diabetes and deafness syndrome (MIDD). We report an observation of a patient with strong suspicion of mitochondrial diabetes.Case presentation: 43-year-old female patient, with diabetes for 5 years on an Insulin Therapy.Anamnesis:&hypen;&...

Introduction: Compared to normal population, patients with neurofibromatosis are at higher risk for the development of benign and malignant tumors. Pheochromocytomas are relatively rare in neurofibromatosis type 1 (NF1), and malignant ones are even rarer.Aim of the presentation: Our aim was to report a malignant pheochromocytoma with multiple metastases in a patient with NF1.Case report: A male patient aged 23 years old, with lapar...

Background: Neuroendocrine tumors present in the MEN-1 syndrome are usually located in pancreatic islets and more than 10% appear de novo, affecting any age group. The debut of a carcinoid tumor is rare, with a prevalence of 2% of bronchial carcinoid tumors. Materials and methods: We present the case of a 49-year-old woman referred from the Oncology clinic for the assessment of thyroid incidentalomas found in a follow-up CT scan of multifocal bronchial c...

Introduction: Pregnancy results in a significant change in pituitary gland size and function.Due to this physiological adaptation, management of pituitary adenomas during pregnancy represents a particularly complex challenge. Aim of this study was to focus on a single referral institution experience with special attention to this subgroup of patients: pregnant woman affected by pituitary adenoma.Materials and methods: This is a des...

Background: Multidisciplinary approach to pituitary disease is highly recommended; it requires a close relationship between expert pituitary surgeons and endocrinologists together with several specialists (e.g. neuroradiologists) in order to provide a high-level standard of care. Although there is evidence that neurosurgeons’ expertise is a key element to achieve better outcomes, also endocrinologists’ role is fundamental but it may sometimes encounter real-life barr...

Background: Patients with CHH and KS have eunuchoid body proportions of the skeleton compared to normal male subjects, characterized by tall stature, and reduced upper-to-lower segment ratio (U/l). Vice versa, steroids exposure deeply differs between CHH and KS at puberty, with both testosterone and estradiol being very low only in CHH. At present, body skeletal proportions comparison between CHH and KS is not available.Aim: To compare anthropom...

Introduction: Pheochromocytomas are catecholamine producing tumors which arise from chromaffin cells within the adrenal medulla. Silent pheochromocytomas are rare entities that do not present with the classical symptoms commonly seen in catecholamine-secreting tumors. Case report: We report a case of 70-year-old-woman patient who presented with left sided abdominal pain and discomfort for 6 months. A preoperative Computed tomography (CT) scan showed a hu...