Endocrine Abstracts

The aim: To study age-dependent changes of bone mineral density of females and males rats in remote terms after hyperthyroidism abolition.Research Object: Research is conducted on 180 white females and males rats of ‘Wistar’ breed. Animals were arranged in the 18 groups: six controls groups (CG) of pre-pubertal, reproductive and old males and females; six groups of rats with the experimental model hyperthyroidism (HTG); six groups of rats 30 da...

Disorders of bone tissue as a complication of hyperthyroidism now become accepted fact. On other side decreasing of serum levels of estrogens in postmenopausal women potentially may increase effects of thyroid hormones on bone tissue.The aim of our study was investigate with DXA the features of loss of bone mass in women suffering from thyrotoxicosis depending of age and thyrotoxicosis duration.Material and methods: There were exam...

A 72-year-old woman was initially referred by her GP to the colorectal service of our Hospital. She had a 4-month history of weight loss, fatigue and appetite loss.The initial blood tests at the GP surgery revealed a normochromic normocytic anaemia.She had a diagnosis of SVT and she was on sotalol. She had never smoked nor she had a history of excess alcohol.In her initial blood tests: Hgb 9 g/dl, albumin 27 ...

Introduction: Cystic adrenal incidentalomas are relatively rare. Large cystic pheochromocytomas are extremely rare and there are few reports of them being clinically silent.Case presentation: We report the case of a 57-years-old man, who was admitted to our clinic for evaluation of a large cystic lesion that was found ultrasonographicaly in a typical check-up. We ordered a CT that revealed a giant right adrenal cyst (91.3×96.8×92.1 mm) with thi...

Aim of research: To determine uric acid level in blood serum and incidents of hyperuricemia among women and men of different age and their relation with some components of metabolic syndrome.Object of research: Women (n=450) and men (n=120), age of examined patients was from 20 to 89 years old. They were divided into the following groups: I group (BMI=18.5–24.9), II group (BMI=25.0–29.9), III group (BMI=30.0–34.9), IV group (...

Research objective: After the Chernobyl nuclear reactor accident, there was a dramatically increase in thyroid cancer incidence in children and adolescents in Belarus, Ukraine and the Russian Federation. The increasing incidence of thyroid cancer in last 10 years not only in former Soviet Union but also in the United States, is real medical problem. ‘Project Chernobyl’ has been established in New-York for early diagnostics of radio induced thyroid cancer among people...

Prolactin was discovered 80 years ago. It is currently viewed by clinical endocrinologists as a hormone of pituitary origin, whose production is negatively controlled by dopamine, whose biological actions relate exclusively to lactation and reproductive functions, for which any genetic disorder is yet to be identified, and whose unique associated pathology is hyperprolactinemia, which is efficiently cured using dopamine agonists. Although there is no debate about the relevance...

Aim of research: To determine uric acid level in blood serum and incidents of hyperuricemia in postmenopausal women and their relation with body mass index (BMI).Object of research: Patients of clinic by the physiology and pathology of bone and joint disease department and Ukrainian medical-scientific center of osteoporosis: postmenopausal women (n=134). They were divided in the following groups depending on BMI: I group (BMI=20.0–24.9) &#150...

Introduction: The period of adolescence is a difficult time for most people and is the time when transition from the paediatric diabetic service to the adult occurs; therefore a smooth transition is essential. The National Service Framework for Diabetes identified transition from paediatric care to adult as an area where protocols could support better care. Placing emphasis on the transition services may help in ensuring effective long-term control and health improvement.<...

Fifty year-old year old gentleman presented unwell whilst on holiday with headache and vomiting. He also reported a clear fluid trickling down his nose. On examination he was pyrexial, photophobic and had demonstrable neck stiffness. Lumbar puncture and a subsequent culture confirmed streptococcal meningitis which responded to antibiotics.His CT scan head suggested a pituitary mass and a subsequent MRI revealed an unusual massive pituitary tumor extendin...