Endocrine Abstracts

ObjectiveTo describe two cases of patients presenting with abdominal pain to the gastroenterologists. These were diagnosed with primary hyperparathyroidism and adrenal insufficiency respectively.MethodsTwo case histories, including detailed results of laboratory tests, are presented, and the findings are discussed.ResultsWe present a 62 year old gentleman who was ...

Primary Carcinoid tumour of Epididymis is a very rare presentation. It accounts to only 0.23% of Carcinoid tumours. Here we present a patient with Primary Carcinoid tumour of Epididymis, which was successfully resected.A 57 year old gentleman with no significant past medical history was seen with painless swelling of his Right testes. He had no symptoms such as weight loss, Diarrhoea or flushing on direct questioning. Examination revealed a Solid, non-te...

Although congenital hypothyroidism is sporadic in the majority, recessive and X-linked inheritance can also occur in monogenic disorders. In familial cases, the finding of genetic variation could identify specific phenotypes and unravel thyroid pathobiology.We describe three siblings born to non-consanguineous parents. The index case, a boy, presented at 1 year of age with severe developmental delay, expressive aphasia and hypotonia. Thyroid function sho...

Pregnancy and lactation-associated osteoporosis (PAO) is a rare syndrome of spontaneous fragility fractures, most commonly vertebral, occurring in late pregnancy or lactation. The aetiology and pathogenesis of this osteoporosis are unknown, and early diagnosis and management are essential because of the severity of the morbidity associated with these fractures. The management includes cessation of breastfeeding, use of specific osteoporosis drugs, and adequate analgesia.<p...

BackgroundRapid induction of eu/hypothyroidism in patients with immune hyperthyroidism has been known to precipitate Thyroid eye disease (TED). Our aim was to investigate the incidence of TED in patients treated with radio-iodine therapy (RIT) at our hospital.MethodsWe examined case notes of 45 patients who underwent radio-iodine therapy for Graves’ disease with 544.7 (95% CI- 522.3 – 567.1) MBq bet...

Background: Hyperinsulinaemia and insulin resistance is observed in both lean and obese women with Polycystic Ovary Syndrome (PCOS). This condition affects 52% of Asian Indian compared to 22% of Caucasian women. Lifestyle changes, particularly diet and exercise can significantly impact the future prevention of type 2 diabetes, dyslipidaemia and hypertension in these patients.Objectives: We hypothesised that regular intensive exercise would be effective i...

This 65 years old lady, who had undergone neck explorations for parathyroid adenoma in 1972 and 2000, presented with vomiting, lethargy, muscle weakness and polyuria. On admission, her serum Calcium was 2.98 mmol/l (2.18-2.63) with elevated parathyroid hormone of 151 pg/ml (10-70). A Thallium-Technetium parathyroid scan was normal but Octreotide scan showed an area of uptake in the superior mediastinum. A MIBI scan followed, which was unhelpful as were ultrasound scan of the n...

Diabetic ketoacidosis and pregnancy related ketoacidosis are the most common forms of ketoacidosis seen in acute medical units. We describe here two rare cases of starvation ketoacidosis.Case 1: 63 years old gentleman with no history of diabetes, presented with persistent vomiting for 48 hours. His admission bloods revealed Serum Bicarbonate of 8, pH 7.19, pCO2 2.7, base excess of -17.8, plasma glucose 5.2 mmol/l and serum alc...

Diabetic ketoacidosis and pregnancy related ketoacidosis are the most common forms of ketoacidosis seen in acute medical units. We describe here two rare cases of starvation ketoacidosis.Case 1: 63 years old gentleman with no history of diabetes, presented with persistent vomiting for 48 hours. His admission bloods revealed Serum Bicarbonate of 8, pH 7.19, pCO2 2.7, base excess of -17.8, plasma glucose 5.2 mmol/l and serum alc...

Case history: A 26-year-old female presented with acute left-sided loin pain. There was a preceding dull ache for two months. She had no dysuria or haematuria. Her past medical history was unremarkable except for rhinosinusitis. Investigations: Abdominal CT revealed oval shaped lesion adjacent to the upper pole of the left kidney. The left adrenal gland could not be separately visualized. The lesion had mass effect on the fundus of the stomach. Adrenal M...