Endocrine Abstracts

Objectives: The study of the real indications for thyroid ultrasound and in which pathological conditions the echography is of real use and not for abuse.Material and methods: In the last 10 years, over 13 000 echographies were performed in 5136 consecutive patients for ‘thyroid disturbances’. In a previous paper we described 7 echographic patterns for thyroid ultrasound (9th ECE). The diagnosis of Hashimoto’s thyroiditis (HT) was consider...

Graves’ thyrotoxicosis frequently occurs after delivery through immune rebound mechanism. A 34 years old patient, in postpartum period was referred to rheumatologist for gradually gait impairment. Examination showed only weakness of pelvic girdle muscles which required an extensive differential diagnosis including: neurological diseases and inflammatory/metabolic/toxic myopathies. Routine lab tests were unremarkable except low cholesterol (128 mg/dl) and slightly increase...

Introduction: Usually, the hormonal profile is normal in patients with empty sella. However, when present, hormonal deficiency most commonly consist in growth disturbance in children and mild hyperprolactinaemia in adults. Hypopititarism with signs of symptomatic dysfunction occurs in <10% of patient with primary empty sella.Case report: A 27-years-old man presented to our department in 2008 with impuberism, micropenis, hypoplasic scrotum, inguinal g...

Introduction: Left hepatic lobe volume (LHLV) has been associated with hyperinsulinemia and insulin resistance in obese women.Aim: To study the correlation between LHLV and body weight, regardless the weight and gender of the patient.Subjects and methods: The left hepatic lobe was evaluated with an echographic probe of 3.5 MHz. The LHLV (cm3) was calculated with the formula: antero-posterior diameter (length)×longit...

Polycystic ovary syndrome (PCOS) is a major source of psychological morbidity and can negatively affect quality of life. The aim of the study was to identify characteristics of self-concept in female patients diagnosed with PCOS (n=22, mean age 26+/− 11 years) and comparative analysis with a control group (n=22).Methods: Psychology questionnaire, selection tests based on geometrical figures/ words and also graph logical analysis were ...

Introduction: Uric acid may increase cardiovascular risk, exerting proinflammatory, pro-oxidant and proliferative actions at the endothelial cell level. Classic and non-classic cardiovascular risk markers cluster in women with polycystic ovary syndrome (PCOS), uric acid being proposed as one of them. The studies available at present regarding serum uric acid levels in PCOS patients are scarce and controversial. The aim of the study was to examine the relationship between uric ...

Polycystic ovary syndrome (PCOS) is a heterogeneous condition affecting 5–10% of reproductive -age female population.The aim of this study was to determine the clinical features, metabolic and hormonal profile in obese and overweight women with PCOS.Patients and method: A total of 102 women (age 31.28±6.05 and BMI 33.02±5.93) with PCOS and 110 (age 32.35±4.96 and BMI 33.05±5.87) matched controls were invest...

Growth hormone deficiency leads to profoundly decreased growth velocity and, when untreated, to pituitary dwarfism. We evaluated growth evolution for one to four years under rGH therapy (0.07 IU/kg/day, subcutaneously) at seventeen idiopathic pituitary dwarves with isolated GH deficiency, 13 boys and 4 girls, with a wide span of age at therapy onset (between 4 and 24 years old). Diagnosis was set subsequent to at least two negative GH stimulation tests. All patients were pre-p...

Hypokalemic periodic paralysis is an uncommon complication of thyrotoxicosis especially in Caucasian women. It is most frequent in east asian and Japanese males and is characterized by recurrent episodes of motor weekness of variable intensity associated with hyperthyroidism. It is usually associated with low plasma potassium levels and is often precipitated by physical activity. This condition is a self limiting disorder that is cured by the treatment of the underlying hypert...

Hormonal treatment (HT) represents the only complete therapy of the consequences of the postmenopausal estrogenic deficiency. Quality of life in postmenopausal women is often compromised. We evaluated the quality of life (appreciated with IQL questionnaire) in 80 postmenopausal women – 40 with intact uterus, treated with natural estrogens associated with progestin, and 40 non-treated women. Group selection (treated/not treated) was made function of the inform consent of t...