Endocrine Abstracts

Diabetes mellitus (DM) is a metabolic disease, which is accompanied by systemic damage to organs, including the central nervous system. Clinically, these changes are associated with cognitive impairment, the pathogenesis of which is also largely heterogeneous.Objective: To evaluate the role of tau-protein in the diagnosis of cognitive impairment in patients with type 1 and type 2 diabetes.Materials and methods: The study was tested...

Actuality: Currently, there is no doubt about the negative effect of diabetes mellitus (DM) on the state of the central nervous system. One of the pathological manifestations are anatomical changes in the brain, which in turn can lead to the development of functional disorders and cognitive decline. Conducting imaging research methods allows us to assess the presence or absence of brain atrophy at an early stage.The aim: To identify the relationship betw...

The goal was to study neuroplasticity in patients with diabetes mellitus using neuroimaging techniques. We examined 80 patients with diabetes mellitus type 1 and 2. All were conducted general clinical examination, neuropsychological testing - MoCa test, test 12 words. All patients underwent continuous glycemic monitoring and HbA1c assessment. An MRI study was also performed on Siemens 1.5 T, the protocol included a standard examination of the brain, a proton spectroscopy, and ...

Actuality: At present, the role of chronic hyperglycemia in type 1 diabetes mellitus (DM1) in the onset of diabetic encephalopathy has been proven. At the same time, violations in the metabolic composition of brain cells were detected in persons with DM1, estimated with the proton magnetic resonance spectroscopy (1H-MRS). However, the relationship between the results of these studies has not yet been studied.The aim: To reveal the relationship...