Endocrine Abstracts

Introduction: Turner syndrome (TS) is a rare genetic disorder characterized by an aberration of the X chromosome, most commonly associated with various comorbidities, such as metabolic disorders, particularly dyslipidemias. The aim of this study is to determine the frequency of dyslipidemias associated with TS and to evaluate the impact of growth hormone (GH) treatment on lipid metabolism.Methods: This is a descriptive and retrospective study of 22 patie...

Introduction: Central diabetes insipidus reflects a serious underlying pathology in children. The etiologies are dominated in pediatric population by: central nervous system (CNS) tumors and malformations, histiocytosis, postoperative, radiation, and trauma injury to the hypothalamic-pituitary region. We report in this work three observations illustrating rare etiologies of pediatric central diabetes insipidus in the endocrinology-diabetology and nutrition department of the Mo...

Introduction: Secondary or primo-secondary amenorrhea suggests central damage of the hypothalamic-pituitary axis or peripheral damage of the reproductive system. It must be carefully investigated with an essential hormonal workup to determine the etiology and initiate the appropriate treatment.Observation: We report the case of a 21-year-old patient, admitted for exploration of a primo-secondary amenorrhea associated with a pituitary tumor syndrome made ...

Introduction: Pseudohypoparathyroidism type Ib are genetic diseases with transmission maternal, defined by a resistance to the action of the parathormone without resistance to the TSH. Clinical manifestations are variable and depend on the severity of hypocalcaemia. We report the case of a patient presenting with type Ib pseudohypoparathyoidia.Observation: This is a 9-year-old child admitted for care and exploration of a severe hypocalcaemia. The patient...

Introduction: Primary hyperparathyroidism is an endocrinopathy characterized by the excessive secretion of parathyroid hormone, most commonly associated with parathyroid adenoma. The osteoarticular manifestations of hyperparathyroidism are currently exceptional. The diagnosis is most often established at the asymptomatic stage by measuring calcium levels and parathyroid hormone.Observation: We report the case of a 67-year-old patient with a history of pa...

Introduction: Rickettsia diseases are infectious, re-emerging, polymorphic, potentially fatal diseases that are widespread worldwide. These are diseases caused by strict intracellular bacteria with a Gram-negative stain associated with arthropods, mainly ticks, but also lice, fleas and other mites. In diabetics, adequate and early management is essential given the risk of developing malignant Mediterranean spotted fever.Observation: We report the case of...

Introduction: Leo Burger’s thromboangiitis obliterans ‘TALB’ is a rare inflammatory, segmental and occlusive disease affecting small and medium-sized arteries and the veins of the extremities of the limbs. It is more common in males and its major aggravating factor is smoking.Observation: We present the case of a 66-year-old patient with a history of chronic smoking at a rate of 25 packs per year, known type 2 diabetic for 10 years, well b...

Introduction: Mayer-Rokitansky-Küster-Hauser syndrome (MRKH) is a rare malformation of the birth canal in women. It is defined as agenesis of the uterus and vagina with normal development of secondary sexual characteristics and a normal karyotype (46, XX). This is an entity with a heavy psychological impact requiring multidisciplinary care.Observation 1: We report the case of a 16-year-old patient with a history of delayed puberty in the sister, who...

Introduction: Thyroid heterotopia is an abnormal location of coexisting normal thyroid tissue with a normal organ and normal location. It is a congenital anomaly due to a defect in the maturation of the thyroid tissues, which is distinguished from ectopic thyroid and from a thyroid cancer metastasis.Observation: We report the case of a 65-year-old patient, with no notable history, who consulted for clinical signs of thyrotoxicosis associating asthenia, t...

Introduction: Graves’ disease is the most common cause of hyperthyroidism. There are three main therapeutic weapons: synthetic antithyroid drugs, surgery and radioactive iodine. The latter represents an effective treatment without noticeable side effects. We report a case of Graves’ disease refractory to iratherapy.Observation: This is a 38-year-old patient, with no notable history, who consulted for Graves’ disease diagnosed with clinical...