Searchable abstracts of presentations at key conferences in endocrinology

ea0009p22 | Diabetes and metabolism | BES2005

The effect of a high fat, high cholesterol diet on blood glucose in pigs

Massey K , Laws J , Perkins K , Beattles S , Filby L , Hatton E , Lomax M , Haskard D , Buckingham J , Jarvelin M , Corson A , Lean J , Clarke L

Epidemiological studies have suggested that in man low birth weight followed by rapid catch-up growth dramatically increase the risk of adulthood diabetes and metabolic syndrome. This experiment investigated the effect of a high fat, high cholesterol post-weaning diet on blood glucose levels of low (L) and normal (N) birth weight pigs.Low (L: <10thpercentile; n=6) and normal (N: 40th - 60th percentile; n=12) birth weig...

ea0032p1008 | Thyroid (non-cancer) | ECE2013

Vitamin D status in autoimmune hypothyroidism

Kota Sunil Kumar , Meher Lalit Kumar , Jammula Sruti , Modi Kirtikumar D

Objective: To investigate vitamin D status in patients with autoimmune hypothyroidism.Methods: The study group consisted of 100 patients with newly diagnosed Hashimato’s thyroiditis and 100 subjects as the control group. Parameters of calcium metabolism, thyroid function tests and 25(OH) vitamin D levels were measured.Results or case presentation: Mean age of the study groups was 33.4±4.8 years with female:male, 72:28. Vi...

ea0031p357 | Thyroid | SFEBES2013

Vitamin D status in autoimmune hypothyroidism

Kota Sunil Kumar , Meher Lalit Kumar , Jammula Sruti , Modi Kirtikumar D

Objective: To investigate vitamin D status in patients with autoimmune hypothyroidism.Methods: The study group consisted of 100 patients with newly diagnosed Hashimato’s thyroiditis and 100 subjects as the control group. Parameters of calcium metabolism, thyroid function tests and 25(OH) vitamin D levels were measured.Results or Case Presentation: Mean age of the study study groups was 33.4±4.8 years with female:male=72:2...

ea0003p52 | Clinical Case Reports | BES2002

Extremely long effects of vitamin D therapy: A near-fatal complication of thyroid surgery

Gable D , Ahlquist J

Vitamin D is commonly used in the treatment of hypoparathyroidism after thyroid surgery. It is well recognised that excess vitamin D therapy leads to hypercalcaemia, and that this effect may be prolonged, lasting upto several weeks with some vitamin D preparations. We describe a case of severe, life threatening hypercalcaemia from vitamin D therapy, in which the duration of action of vitamin D was exceptionally long. A 51 year old lady presented with acute, severe haemorrhagic...

ea0029p210 | Calcium &amp; Vitamin D metabolism | ICEECE2012

Longitudinal changes in serum 25-hydroxyvitamin D levels of older persons during 6 and 13 years of follow-up

van Schoor N. , Knol D. , Deeg D. , Heijboer A. , Lips P.

Background: Vitamin D deficiency is very common in older persons. It is not clear how serum 25-hydroxyvitamin D (25(OH)D) levels change during aging.Objective: To examine longitudinal changes in serum 25(OH)D levels in two representative cohorts of Dutch older persons during 6 and 13 years of follow-up, respectively.Methods: Data of the Longitudinal Aging Study Amsterdam (LASA) were used, an ongoing cohort study in older persons. T...

ea0007p12 | Bone | BES2004

Investigation of seasonal reference intervals for 25-Cholecalciferol (Vitamin D)

Donaldson A , Leung Y , Jackson D , Hill P , Chapman R

Vitamin D is essential to the control of calcium homeostasis and is mainly provided by exposure to sunlight. In the UK circulating Vitamin D is subject to seasonal variation with peak values occurring in early Autumn and trough values in late Spring. Requests for Vitamin D assays are increasing but few laboratories quote seasonal reference ranges and many commercial suppliers quote reference ranges for populations living in warmer, sunnier climates. This study established seas...

ea0077lb7 | Late Breaking | SFEBES2021

Vitamin D deficiency in female healthcare workers during a pandemic

Piec Isabelle , Cook Laura , English Emma , Fraser William D

One of the most significant health measures implemented during the COVID-19 pandemic has been extended periods of lockdown. Vitamin D is essential for many biological functions including pregnancy and bone health and modulate the immune system. Many studies also suggested a beneficial effect of replenished stores of vitamin D (25(OH)D >50 nmol/l) against severe and long term COVID-19 and self-supplementation is recommended by the government. Here we report on the vitamin D...

ea0029p331 | Cardiovascular Endocrinology and Lipid Metabolism | ICEECE2012

Vitamin D serum levels and cardiovascular risk factors in postmenopausal women

Bohdanowicz-Pawlak A. , Milewicz A. , Jedrzejuk D. , Szymczak J. , Arkowska A.

Results of several clinical studies have suggested that there is an excess risk of cardiovascular disease in persons with vitamin D deficiency.We examined association between serum levels of vitamin D - 25(OH)D and select cardiovascular risk factors in 254 postmenopausal women at a mean age of 55.38±205 years.Vitamin D levels, lipoproteins, TNF-α, Interleukin 6, adiponectin, insulin (using RIA methods) and glucose were as...

ea0029p1223 | Obesity | ICEECE2012

Effect of obesity on vitamin d and parathormone levels

Baser H. , Tuzun D. , Saglam F. , Caner S. , Ersoy R. , Cakir B.

Aim: In this study our aim was to investigate the relationship between obesity and vitamin D and hyperparathyroidism.Material and Method: 127 healthy persons included in this study. Study group were divided into four groups according to body mass index (BMI). Group 1 (n=35) BMI 18.5–24.9 kg/m2, Group 2 (n=35) BMI 25–29.9 kg/m2, Group 3 (n=35) BMI 3.0–34.9 kg/m2, Group 4 (n=22) BM...

ea0029p198 | Calcium &amp; Vitamin D metabolism | ICEECE2012

Serum IGF1 concentration is positively associated with 25-hydroxyvitamin D level and increases upon treatment with vitamin D

Ameri P. , Bovio M. , Leoncini G. , Arvigo M. , Minuto F. , Ferone D. , Murialdo G.

IGF1 concentrations have been reported to increase with 25-hydroxyvitamin D (25(OH)D) values in population studies, but it is unclear whether this association expresses a cause-effect relationship. Mice genetically deficient of steroid receptor coactivator 3, a transcriptional coactivator for the nuclear vitamin D receptor, have significantly lower circulating IGF1 levels than wild-types.We measured serum fasting 25(OH)D and IGF1 by enzyme- and radioimmu...