Endocrine Abstracts

Background: Colorectal cancer is the world’s third most common cancer. The prognosis is mainly determined by the stage of the tumor, but several other factors related to the patient, such as co-morbidities, may also have an impact on the disease course. The aim of our study was to assess the prognostic value of diabetes and obesity in colorectal cancer.Methods: We conducted a retrospective study including patients diagnosed with primary colon or rec...

Background: Malnutrition and weight loss are well-recognized complications of Crohn disease (CD), however nutritional routine assessment is not commonly performed, resulting in under-detection and under-treatment of both malnutrition and nutrient deficiencies. In fact, a number of nutrition screening tools are available including the Nutritional Risk Index (NRI).Aim: The aim of this study was to investigate the prevalence and the associated factors of ma...

Introduction: Different studies indicated the possible association between celiac disease and Helicobacter pylori (HP) infection, although this evidence is not consistently accepted. The aim of our study was to determine whether HP infection and celiac disease were associated among patients undergoing upper gastrointestinal endoscopy.Methods: Between January 2017 and June 2018, patients undergoing upper gastrointestinal endoscopy with both gastric and du...

Different studies indicated the possible association between lymphocytic gastritis and both celiac disease and Helicobacter pylori infection, although this evidence is not consistently accepted.Objective: We aimed to determine whether Helicobacter pylori infection and celiac disease were associated among patients undergoing upper gastrointestinal endoscopy.Methods: Between January 2016 and June 2017, patients over...

Introduction: Steatosis has become an important issue in hepatitis C, due to the injury it can cause in a chronically ill liver. In chronic hepatitis C patients, the prevalence of steatosis ranges from 40–86%. Steatosis was significantly associated with the lack of response using PEG-IFN and ribavirin. The aim of our study was to determine the prevalence of hepatic steatosis in chronic hepatitis C and determine its impact on the therapeutic response using new direct antiv...

Introduction: Disorders of glucose metabolism are often present in chronic liver diseases. The aim of our study is to determine the prevalence and factors associated with type 2 diabetes in patients with cirrhosis.Methods: This is a retrospective study collecting all patients with cirrhosis between January 2010 and December 2019.Results: During the study period, 166 patients were included. Of these patients, 47 patients had type 2 ...

Introduction: The main objective in the management of primary hypothyroidism is to normalize thyrotropin (TSH) level with Levothyroxine replacement therapy. The optimal dose of Levothyroxine may be affected by several factors such as age, gender, body weight, some medical disorders and drugs intake. The aim of this study was to assess the relationship between thyroid antibody titers and Levothyroxine dose in patients with primary hypothyroidism secondary to Hashimoto thyroidit...

Background: More than 1.9 billion people in the world are suffering from overweight. Damages can be caused to the liver such as fatty liver or even Cirrhosis. The aims of this study are to determine the prevalence and the impact of steatosis and overweight on therapeutic response in chronic hepatitis B.Methods: This is a descriptive transversal study enrolled from 01/2010 to 09/2018. All patients with chronic hepatitis B investigated by liver biopsy were...

Introduction: Diabetes in the elderly is a major public health problem in Tunisia. Its prevalence increases with aging population. The aim of this study was to determine the particularities of insulin-requiring diabetes in elderly patients in hospitals.Methods: This was a retrospective cross study about insulin-treated diabetics admitted in our institute between August and October 2016 for uncontrolled diabetes. Was considered as elderly diabetic any pat...

Background: Overweight is becoming increasingly more common among patients with inflammatory bowel disease and plays a role in the development and course of the disease especially in Crohn’s disease (CD). However, there is currently little data on his impact on the evolutionary genius of CD. The aim of this study was to assess the impact of overweight on the epidemiological, clinical, therapeutic and progressive characteristics of CD.Patients and Me...