Endocrine Abstracts

Background and Aims: The type 1 diabetes mellitus (T1DM) remains one of the main public healthcare problems worldwide. Recent clinical studies have shown a promising stem cell role in the treatment of T1DM. We evaluated the closest therapeutic effect of autologous mesenchymal stem cell transplantation (AMSCT) on carbohydrate metabolism markers in type 1 diabetes mellitus (T1DM) patient in the honeymoon phase.Materials and Methods: C-peptide (ng/ml), glyc...

Background: Dysglycemia is independently associated with increased risk of death in critically ill adults. The aim of this study was to analyze the differences in glycemic control between the diabetic and non- diabetic patients underwent acute myocardial infarction (AMI).Materials and methods: Retrospective descriptive study of patients with acute myocardial infarction (AMI) admitted to the intensive care unit (ICU) from January to June 2016, including b...

Background: The number of patients with type 2 diabetes with mental problems will increase in the coming years1. The fight against diabetes cannot be reduced only to the competent prescription of medications, but should be carried out comprehensively taking into account numerous barriers.Aims: The objective of this study was to investigate prevalence and impact of anxious and depressive reactions among persons living with type 2 diabetes in Be...

BackgroundThe prevention of complications and improvement of metabolic control and state of health in diabetes cannot be effective only with medications. And now we need to develop different approaches – not only up to date pharmacological treatment of diabetes, but change the Self-Management Behavior among patients with Type 2 Diabetes.AimsTo assess the current status of diabetic self-management behavio...

BackgroundThe current COVID-19 pandemic is the worst from world infection outbreaks have occurred frequently in the last two decades, and it has led to significant mortality. Although the respiratory system is the most prominent target of SARS-CoV-2, extrapulmonary involvement are important contributors of its morbidity and mortality. A number of symptoms occur in these patients due to the involvement of various endocrine glands. The nervous, endocrine, ...

BackgroundThe prevention of complications and improvement of metabolic control and state of health in diabetes cannot be effective only with medications. And now we need to develop different approaches – not only up to date pharmacological treatment of diabetes, but change the Self-Management Behavior among patients with Type 2 Diabetes.AimsTo assess the current status of diabetic self-management behavio...

BackgroundIt has often been argued that important psychosocial factors such as depression, anxiety and emotional stress can influence self-help behavior and therefore negatively affect glycemic control. In turn, the reduced quality of life due to chronic illness is a mediated cause of poor glycemic control. Also, attention is drawn to the prevalence of cognitive impairments and dementia.Aims1) to assess the p...

As known, the number of obese people in the world exceeds 50% of the total population. Тo search the causes of obesity development many researchers pay attention to metabolites of intestinal microflora among which the main ones are short–chain fatty acids (SCFA): acetate (C2), propionate(C3), butyrate(C4). Hormones of food behavior produced by visceral adipose tissue (leptin) and cells of the gastrointestinal tract (ghrelin) also play an important role in the devel...

The key factor in the pathogenesis of both T2D and NAFLD is insulin resistance, which causes the lipids accumulation in hepatocytes and an increase of the lipid peroxidation, the production of reactive oxygen species and the development of inflammation. It has been shown that the main metabolic products of the saccharolytic microflora-short-chain fatty acids (SCFA), such as acetic (Ac), propionic (Pr) and butyric (Bu), can have an anti-inflammatory effect through their suppres...

Metabolic diseases are among the most important diseases in western societies and usually related to obesity. Dietary interventions are recommended for treatment and include both strategies with reduced caloric intake and alterations in macronutrient composition. Metabolism must be assumed to be regulated differently in females and males. In previous studies we demonstrated that low carbohydrate high fat (LCHF) diets affect GH/IGF-I axis in male rats. We know investigated whet...