Searchable abstracts of presentations at key conferences in endocrinology

ea0090ep37 | Adrenal and Cardiovascular Endocrinology | ECE2023

Giant Cystic Asymptomatic Pheochromocytoma

Kanburoglu Meletli Ozlem , Birinci Cigdem , Bilginer M. Cuneyt , Coskun Hulya , Nuhoglu Irfan , Ucuncu Ozge , Kocak Mustafa

Introduction: Giant and cystic catecholamine-secreting tumors are usually asymptomatic and detected incidentally during imaging. A simple mobilization of the tumor can cause the release of catecholamines into the blood and is therefore associated with high morbidity and mortality. Here, we aimed to present a patient with a 13 cm mass in the left adrenal gland and diagnosed as giant cystic pheochromocytoma.Case Report: A 62-year-old male patient presented...

ea0090ep50 | Adrenal and Cardiovascular Endocrinology | ECE2023

Autonomic Cortisol-Secreting Adrenal Mass Containing Extramedullary Hematopoiesis Foci

Kanburoglu Meletli Ozlem , Birinci Cigdem , Bilginer M. Cuneyt , Coskun Hulya , Nuhoglu Irfan , Ucuncu Ozge , Kocak Mustafa

Introduction: Extramedullary hematopoiesis (EMH) is most commonly seen in reticuloendothelial system tissues such as liver, spleen and lymph nodes. Rarely, it can be detected in non-hepatosplenic atypical localizations such as the adrenal glands. Although the underlying mechanism is not clearly elucidated, it is suggested that the adrenal glands have hematopoietic activity in the fetal period and EMH may develop from the remains here due to chronic anemia. We aimed to present ...

ea0090ep479 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

A Rare Complication of Diabetes: Hemiballism Syndrome Associated with Non-ketotic Hyperglycemia

Meletli Ozlem Kanburoglu , Birinci Cigdem , Cuneyt Bilginer M. , Coskun Hulya , Nuhoglu Irfan , Ucuncu Ozge , Kocak Mustafa

Introduction: Hemiballism is a rare hyperkinetic movement disorder characterized by involuntary, violent, coarse and wide-amplitude movements involving the ipsilateral arm and leg. Here, we aimed to present a case diagnosed as hemiballism due to non-ketotic hyperglycemia.Case Report: A 60-year-old female patient presented to the emergency department with involuntary movements in the right half of the trunk for 10 days. It was a large amplitude proximal e...

ea0090ep758 | Pituitary and Neuroendocrinology | ECE2023

Pituitary apoplexy in cabergoline-resistant macroprolactinoma

Meletli Ozlem Kanburoglu , Birinci Cigdem , Bilginer M. Cuneyt , Coskun Hulya , Nuhoglu Irfan , Ucuncu Ozge , Kocak Mustafa

Introduction: Pituitary apoplexy is a life-threatening clinical syndrome that develops as a result of bleeding or infarction in a pituitary adenoma. Here, we aimed to present a case of cabergoline-resistant macroprolactinoma who developed pituitary apoplexy.Case Report: A 40-year-old male patient presented to neurology 2 years ago with severe headache. Brain magnetic resonance imaging (MRI) revealed a 15.5×18×21 mm macroadenoma in the pituitary...

ea0090ep891 | Pituitary and Neuroendocrinology | ECE2023

Suprasellar Germinoma with Hypopituitarism and Central Diabetes Insipidus

Kanburoglu Meletli Ozlem , Birinci Cigdem , Cuneyt Bilginer M. , Coskun Hulya , Nuhoglu Irfan , Ucuncu Ozge , Kocak Mustafa

Introduction: Germinomas, which are the most common germ cell tumors of the central nervous system, may present with different symptoms depending on the location and are localized in the 20-30% suprasellar region. Here, we aimed to present a case of suprasellar germinoma with central diabetes insipidus, hypogonadism and secondary adrenal insufficiency.Case Report: A 27-year-old male patient presented with dry mouth, polydipsia, polyuria and nocturia for ...

ea0073aep473 | Pituitary and Neuroendocrinology | ECE2021

Panhypopituitarism without pituitary ischemia after hantavirus infection

Tufekci Damla , Gunay Yasemin Emur , Demir Ahmet Suat , Guvercin Beyhan , Bilginer Muhammet Cuneyt , Coskun Hulya , Nuhoglu Irfan , Ucuncu Ozge , Kaynar Kubra , Kocak Mustafa

IntroductionHantaviruses are a group of viruses causing hemorrhagic fever with renal failure syndrome (HFRS). HFRS is a disease characterized by bleeding, thrombocytopenia, increased vascular permeability, and acute renal failure. Hypopituitarism associated with HFRS often results from necrosis in the pituitary gland caused by ischemia or infarction. HFRS may be difficult to diagnose due to its unclear clinical features. In this report, we present a pati...

ea0029p1166 | Nuclear receptors and Signal transduction | ICEECE2012

Evaluation of K+ flux-dependent regulation of mitochondrial potential (ΔΨm) by α-adrenergic agonist phenylephrine in single hepatocytes

Malyukina M. , Kavok N.

It is generally accepted that hepatic responses to α-adrenergic agonists are dependent on the redistribution of intracellular and also extracellular Ca2+. Besides, phenylephrine induces significant K+ flux changes and plasma membrane hyperpolarisation. Earlier it was shown that K+ channel blockers as well as chelating of extracellular Ca2+ with EGTA could inhibit phenylephrine-induced metabolic responses and activation of mitoch...

ea0090ep613 | Endocrine-related Cancer | ECE2023

A Rare Case; Ectopic ACTH Syndrome Caused by Metastatic Germ Cell Tumor

Meletli Ozlem Kanburoglu , Birinci Cigdem , Bilginer Cuneyt , Coskun Hulya , Nuhoglu Irfan , Ucuncu Ozge , Kocak Mustafa

Introduction: Although ectopic ACTH syndrome (EAS) is most commonly seen in cancers with neuroendocrine differentiation, it is not a common condition in germ cell tumors. Here we report a rare case of EAS due to metastatic germ cell tumor.Case report: A 53-year-old male patient presented with fatigue, weakness, swelling in both legs and weight loss for 3 months. He had type 2 diabetes and no history of smoking or alcohol. In the physical examination, the...

ea0090ep1014 | Thyroid | ECE2023

A patient with thyroid lymphoma diagnosed during follow-up with benign thyroid nodule

Birinci Cigdem , Coskun Hulya , Ucuncu Ozge , Bilginer Cuneyt , Kanburoglu Meletli Ozlem , Kocak Mustafa , Nuhoglu Irfan

Objectives: Primary thyroid lymphoma constitutes 0.5-5% of all thyroid malignancies. Its incidence is two per million persons. Patients usually present with rapidly growing masses in the thyroid their sixth-seventh decades. The disease is frequently accompanied by chronic Hashimoto’s thyroiditis. Most tumors are B-cell derived non-Hodgkin’s lymphoma.Case report: An 84-year-old male patient presented with a palpable swelling in the neck. Ultraso...

ea0049ep843 | Clinical case reports - Pituitary/Adrenal | ECE2017

Coexistence of acromegaly and rheumatoid arthritis: presentation of three cases

Ersoy Reyhan , Bestepe Nagihan , Faki Sevgul , Bilginer Cuneyt , Ozdemir Didem , Erten Sukran , Cakir Bekir

Introduction: Musculoskeletal system is widely affected in acromegalic patients which might cause difficulties in the diagnosis and treatment of inflammatory rheumatological diseases. Here, we report coexistent rheumatoid arthritis (RA) in three acromegalic patients presenting with continuing joint and back pain although acromegalic state was in remission.Case 1: A 64 years old female patient with acromegaly and macroadenoma had undergone transsphenoidal...