Endocrine Abstracts

Introduction: Diabetes is a serious disease that can lead to a depression of the immune system and thereby it is incriminated in serious complications of many infectious diseases among which is Covid 19. The aim of our study is to determine the virulence of SARS-COV-2 in diabetic patients.Methods: This is a transversal study conducted in the department of epidemiology at Fattouma Bourguiba Hospital in Monastir, in October 2020. The data was collected fro...

Background: Opportunistic screening is more efficient than population screening for diabetes mellitus. The aim is to describe the prevalence of unrecognized diabetes mellitus (DM) among out-patients clinic attending in a major hospital in Basrah, Southern Iraq.Methods: A cross-sectional observational study. The study conducted for the period between January 2006 to end of July 2007. Patients, who attended the out-patient clinic in Al-Faiha hospital in Ba...

Introduction: Autoimmune polyglandular syndrome APS type 2 is a rare polygenic disease associationg endocrine autoimmune affection but also other auto immune diseases. The chronology is variable. We report in this context a case of APS associating a Hashimoto thyroiditis, a premature ovarian deficiency and an Addison disease revealed later.Case Report: A 33 year-old women consulted in 2018 for asthenia and spaniomennorrhea. The diagnosis of peripheral hy...

Background: Plantar pressure and pressure-time integral are two important factors for creating foot ulcer in diabetic patients. Increasing foot contact area with a metatarsal pad has been reported as one of the best strategies to decrease the risk of ulcer; but there is no clear guideline to determine optimal length of metatarsal pad.Objective: The purpose of present study was to determine the effects of metatarsal pad length on peak plantar pressure and...

Toll-like receptor 4 (TLR-4) plays an important role in innate immunity. Changes in the reduction–oxidation balance of tissues can lead to a pro-inflammatory state and insulin resistance typically seen in diabetes. An action thought to be mediated by TLRs. Omega-3 fatty acids and peroxisome proliferator activated receptor gamma (PPAR-γ) agonists as pioglitazone are currently used for decreasing inflammation in diabetes.Aim: The aim of this stud...

Objectives: Patients with metabolic syndrome who presents with vascular, metabolic or bone disorders of recent onset, or are difficult to control, or are progressively deteriorating is potentially linked to cortisol excess the aim of the study is to evaluate the prevalence of occult CS in metabolic syndrome patients.Method: In a cross-sectional study, 30 females with metabolic syndrome chosen from Endocrinology Clinic without any phenotypical features of...

Introduction: A 77-year-old man with glipizide treated type 2 diabetes presented acutely unwell, with weakness, intermittent breathlessness, and poor glycaemic control (previously well control with HBA1c of 42 mmol/mol). Initial assessment showed body weight of 74.5 kg, mild leg oedema, blood pressure of 190/100 mmHg, expiratory wheeze, oxygen saturation 91% and PO2 7.8 mmHg on air. Chest XR showed chronic right lower lobe shadowing and a bulky hilum. His plasma glu...

IntroductionMarfan syndrome is a rare autosomal dominant genetic disease resulting from a mutation in the gene encoding type 1 fibrillin (FBN1), which is a glycoprotein in the composition of elastic fibers in connective tissue. It mainly affects the cardiovascular, musculoskeletal and ocular systems.Case presentationWe report the case of a 14-year-old girl, with no particular history, referred to an endocrino...

Introduction: Maternal thyroid deficiency can induce serious adverse events on both mother and fetus during the whole period of pregnancy. The purpose of this study was to determine various epidemiological aspects of thyroid dysfunction among persian pregnant women.Methods: Four hundred-eighty pregnant women with a mean age of 26.9±5 regardless of their gestational age were registered. After recording their medical history, serum samples were collec...

Background and aimDiabetes is the leading cause of adult blindness due to retinopathy. Serum uric acid levels independently predict the development of micro vascular complications. In this study, we analyze the relationship between serum uric acid (SUA) levels with the development and the severity of diabetic retinopathy(DR) in patients with type 2 diabetes mellitus (T2DM).Patients and MethodsA total of 100 T...