Endocrine Abstracts

Introduction: We aimed to investigate serum galanin-like peptide levels and its’correlation with hormonal and metabolic parameters in patients with polycystic ovary syndrome (PCOS)Material and Methods: The study included 48 women (age range, 18-44 years) with a diagnosis of PCOS and control group that included 40 healthy females (age range, 18-46 years). Body mass index (BMI), waist circumference, Ferriman-Gallwey score, was evaluated and plasma glu...

Heterophilic antibodies are well-known interferent factors affecting most immunoassays. However, they have been poorly evaluated in routine clinical practice. Definition of Subclinical Cushing’s Syndrome (SCs) has been arbitrary and prevalence has shown significant variations related with the diversity of the diagnostic tests. In most of the guidelines a low or suppressed corticothropin (ACTH) level has been suggested as an important predictor of SCs. Here, we sought to i...

Objective: Polycystic ovary syndrome (PCOS) is a common endocrine metabolic disorder that affects 5–10% of women of reproductive age. In various studies, it was found to be associated with subclinical hypothyroidism. Serum TSH levels were also reported to be increased in obese individuals. In order to define the impact of obesity on the subclinical hypothyroidism observed in patients with PCOS, we aimed to investigate subclinical hypothyroidism both in lean and overweight...

Subclinical Cushing’s syndrome (SCs) is used to refer to an adrenal incidentaloma with subtle autonomous cortisol secretion and without typical signs and symptoms of hypercortisolism. Diagnostic criteria are uncertain and arbitrary. In this study we aimed to investigate the power of adenoma size as an independent predictor of SCs.Dokuz Eylul University Adrenal Tumours Study Group database includes 596 patients by January 2016. Briefly, there are 332...

Introduction: Natural history of adrenal incidentalomas has not been totally understood. Current data from subjects with adrenal incidentalomas demonstrated an increased rate of metabolic disturbances and cardiovascular risk. It has been shown that subjects with subclinical cortisol excess were more susceptible to diabetes, hypertension, and obesity. However, there is no data regarding prospective cardiovascular risk evaluation in subjects with subclinical Cushing’s syndr...

Background and aim: Differentiated thyroid cancers are the most common endocrine cancer types. They are more common in women, but the prognosis tends to be poorer with men. We aimed to evaluate male and female patients with differentiated thyroid cancer.Subjects and methods: This retrospective study was performed in last 5 yearly hospital records of our hospital. All data about the patients’ conditions were obtained from hospital information system ...

Introduction: Primary hyperparathyroidism is associated with numerous cardiovascular complications including hypertension, left ventricular hypertrophy and calcification of cardiac valves. However, guidelines from expert panels and NICE have not included cardiovascular complications as an indication of parathyroidectomy. This literature review will be focused on benefits of parathyroidectomy on cardiovascular complications of primary hyperparathyroidism....

Objective: Acromegaly is associated with increased cardiovascular morbidity and mortality. But the data about the evaluation of coagulation and fibrinolysis in acromegalic patients is very limited and to our knowledge, platelet function analysis has never been investigated. So we aimed to investigate the levels of protein C, protein S, fibrinogen, antithrombin 3, and platelet function analysis in patients with acromegaly.Methods: Thirty-nine patients wit...

Introduction: Wolfram syndrome, is a rare autosomal recessive genetic disorder that is characterized by diabetes mellitus (DM), diabetes insipidus (DI), optic atrophy, and sensorineural deafness as well as various other possible disorders. DM is the first manifestation, and optic atrophy also onsets in the first decade of life. The onsets of DI and sensorineural deafness are in the second decade, urinary tract abnormalities are in the third decade, and neurologic abnormalities...

İntroduction: Polycystic ovary syndrome (PCOS) is associated with risk of cardiovascular disease (CVD). Endocan is potential immunoinflammatory and endothelial dysfunction marker that may be linked to CVD. This study aimed to evaluate the risk of CVD in PCOS patients and to identify the novel biomarker for CVD risk.Material and methods: We analyzed 52 premenopausal women with PCOS and 59 healthy controls. Clinical, biochemical parameters and endoca...