Endocrine Abstracts

Background: The detection of thyroid incidental uptake of radiopharmaceuticals has been increasing. Those detected by 18F-fluorodeoxyglucose positron emission tomography (PET) have been associated with a significant risk of malignancy (8–64%). Gallium-68 (Ga-68) labelled peptides are now the standard imaging modality for staging neuroendocrine tumours (NET). Its high sensitivity has increased the discovery of incidental findings. The aim of this study was to ev...

Introduction: Prevalence of hypothyroidism is 2–5% in women in the reprodutive age group. Hypothyroidism can affect fertility due to anovulatory cycles, luteal phase defects, hyperprolactinemia and sex hormones imbalance. Some data also report that TSH levels are inversely proportional to the fertilization rate at ART (assisted reproductive technologies).Objective: To evaluate if a relationship exists between pregnancy rates in women undergoing ...

Introduction: Primary thyroid lymphoma is rare and accounts for less than 5% of all thyroid malignancies. The risk is almost 60 times higher in those with thyroiditis and is more common in females, with a ratio of 4:1. The most frequent local symptom is a rapidly enlarging thyroid gland along with the resultant obstructive symptoms. Fine needle aspiration is the initial diagnostic procedure for thyroid tissue sampling. The main differential diagnosis is anaplastic thyroid carc...

Introduction: Type 2 diabetes mellitus (T2DM) is a chronic disease, with prevalence increasing worldwide and its complications are major causes of early morbidity and mortality. Recent guidelines suggest the individualisation of glycaemic targets and glucose-lowering therapies.The aim of this study was to determine the quality of care provided to type 2 diabetic patients in our institution, analysing metabolic control, cardiovascular risk factors and pre...

Background and aims: Type 2 Diabetes Mellitus affects a growing number of people allover the world. It is associated with serious complications. Several studies have shown that it is possible to prevent and minimize type 2 diabetes complications if it is treated appropriately over time. In our Hospital there is, since 1998, an outpatient clinics of diabetes. This study aimed to determine the quality of care provided to diabetic patients in our institution.<p class="abstext...

Introduction: Adult nesidioblastosis is a rare entity that has motivated the publication of several case reports, but long-term outcomes are rarely described. Distal or sub-total pancreatectomy is indicated in cases of severe symptoms or lack of response to medical treatment. We report the case of a patient with persistent nesidioblastosis after pancreatectomy keeping under medical treatment for 24 years.Clinical case: Woman currently with 81-years old, ...

Introduction: Pituitary aplopexy is rare (0.6 to 12.3%). Sudden expansion of pituitary tumor, from hemorrhage or infarction, may lead to permanent vision loss, paresis or death. We describe two cases of apoplexy as the initial manifestation of pituitary tumor.Case 1: Male, 30 years, healthy, observed in the emergency room (ER) complaining of headache, visual deficit and left ptosis for 3 days. He had left ptosis and bilateral paresis of the IV pair. Magn...

Introduction: Hypogonadism is common and occurs prematurely in human immunodeficiency virus (HIV)-infected men, being hypogonadotropic hypogonadism (HH) more frequent. However, HH with very low testosterone has not been described. We present three HIV-infected men with severe HH and normal pubertal development.Case report: Three HIV-infected men, with HIV-1 diagnosis at the ages of 22, 34 and 35 years. Two of them had depressive syndrome, one treated wit...

Background: Pituitary apoplexy occurs when a tumor undergoes acute hemorrhage, infarct, or both. This often leads to acute severe symptoms (clinical) but can also occur without them and diagnosed on CT/MRI, surgery, pathology (subclinical). To investigate clinical and subclinical apoplexy in nonfunctioning tumors (n=221) from our database.Design: Retrospective review of clinical presentation, tumor characteristics and outcome of 24 patients, 11 fe...

Introduction: Hypoparathyroidism treatment is aimed to achieve a serum calcium at the lower limit of normal providing symptom resolution and preventing complications such as urolithiasis and renal impairment. Milk-alkali syndrome (MAS) incidence has been gradually rising associated with the increase of calcium carbonate and vitamin D supplementation. The classic triad is characterized by metabolic alkalosis, hypercalcemia and renal failure.Case report: A...