Endocrine Abstracts

Introduction: The diabetic foot is a major public health problem with a significant socio-economic impact. In the presence of a trophic disorder land filling is a key element of care. The objective of our study is to identify the means and indications, to evaluate the contribution of the discharge in the prevention and the cicatrization of lesions of the diabetic foot.Methods: This was a prospective study conducted from September 2017 to July 2018. Inclu...

Introduction: The frequent polypharmacy in diabetic patients, because of the complications of the disease, drug interactions can occur when two or more drugs are taken in combination. The objective of our work was to determine the relative frequency of these drug interactions, to identify the types and to evaluate the impact or the repercussion of these in the diabetic, in order to deduce the practical behaviors.Patients and methods: Prospective study, c...

Introduction: The pituitary adenoma is a benign hyperplasia of the pituitary gland; it often implies the presence of pathologies of the thyroid gland. The relation between the thyroid volume, the rate of IGF1 and the duration of the disease is not well specific, long time the secretion of GH and IGF1 have been associated with disorders of thyroid function.Presentation of the case: We report the observation of a 37-year-old woman operated on in 2016 with ...

Introduction: Thyroid dermopathy is a non-frequent manifestation of autoimmune thyroiditis. It complicates a small percentage of patients and is usually associated with ophtalmopathy and acropachy.Observation: A 46-year-old man presented to our department of endocrinology at the university hospital of Casablanca with 3 years history of Graves’ disease, developed gradual onset of exophthalmos and bilateral leg oedema starting from his pretibial areas...

Purpose: The evaluation of body composition using indirect techniques is used to estimate the nutritional status of patients. The objective of our study was to determine the profile of patients’ body composition according to the bioelectrical impedance meter and to study its relationship to body mass index and waist circumference.Patients and methods: Cross-sectional study, conducted over 9 months from March to December 2018, in the endocrinology de...

Introduction: The incidence of diabetes mellitus is increasing worldwide and is a major public health problem. The aim of our study was to determine the relationship between fat and visceral mass with the glycemic balance of diabetic patients.Patients and methods: A prospective study, conducted over 9 months from March to December 2018, in the endocrinology department of Ibn Rochd University Hospital of Casablanca, in 75 patients with type 2 diabetes and...

In ACTH-independent macronodular adrenal hyperplasia (AIMAH) causing Cushing’s syndrome, cortisol secretion is controlled by illegitimate membrane receptors. In the normal adrenal gland, agonists of 5-HT4 receptors have a powerful effect on aldosterone secretion but little effect on cortisol secretion in vitro.The aim of our study is to describe the clinical and hormonal features of patients diagnosed with aberrant serotonin receptor expres...

Giant-cell tumor is a skeletal disorder that occurs secondarily to hyperparathyroidism and is caused by long-term stimulation of parathyroid hormone (PTH) excess. The overactivity and proliferation of osteoclasts stimulated by PTH breaks down bone and leads to replacement of bone matrix and thinning of the cortex. True giant-cell tumor is a rare jaw osteolytic benign tumor belonging to the larger family of giant-cell tumors.We report the case of a 47 yea...

Background: Gigantism indicates excessive secretion of growth hormone (GH) during childhood Pituitary gigantism is very rare and the description of the disease is limited to small series and case reports. Here, we report a case of pituitary gigantism in a child revealed with visual defect.Case report: A 14-year-old boy presented with headache and left visual loss. On examination, he had visual acuity in his right eye of 2/10. His height was 178.0 cm (3 c...

Background: Hoffmann syndrome is a rare form of hypothyroid myopathy in adults characterized by presence of muscle weakness, stiffness and pseudo-hypertrophy. Here, we report a case of Hoffman syndrome aggravated by statin therapy.Case report: We describe the case of a 60 year old woman with primary hypothyroidism who presented with fatigue, cold intolerance, constipation, exertional breathlessness, progressive proximal muscle weakness and swelling of th...