Endocrine Abstracts

Introduction: Glucocorticoid replacement therapy may result in long-term morbidities, including cardiovascular diseases which can increase cardiovascular risk. The study was aimed to assess the impact of life-long glucocorticoid replacement therapy on cardiovascular parameters in patients with Addison disease (AD).Patients and Methods: This cross-sectional study was conducted assess cardiovascular events in patients followed for AD for at least 5 years, ...

Background and aims: Pituitary adenomas (PA) are small, generally benign tumors found in the pituitary gland. PA in men are rare However, they are characterized by the frequency of invasive and aggressive tumours, which makes their management difficult. The aim of this study is to clarify radiological characteristics of pituitary adenomas in men. Materials and methods: Retrospective descriptive study of 80 adult men with PA, hospitalized in the endocrinology department from 19...

Introduction: Prolactinomas in men are rare but are characterised by their giant and invasive nature. They present with signs of hypogonadism and mass effect. The aim of this study is to clarify the clinical, biological, radiological and therapeutic features of Prolactinomas in men.Patients and methods: Retrospective descriptive study including 27 adult males with a prolactin pituitary adenoma hospitalized in the endocrinology department of the Hedi Chak...

IntroductionPrimary ovarian failure currently represents an increasingly frequent cause for consultation in endocrinology, from 4 to 18 % of the causes of primary amenorrhea and 10 to 28 % of the causes of secondary amenorrhea.ObjectivesIn this context, we report a retrospective study of 50 patients followed between 2000 and 2020 for early menopause, in order to assess the etiologies and risk factors favourin...

BackgroundAmiodarone is a widely-used anti arrhythmic medication. Amiodarone-induced hyperthyroidism (AIH) develops in 3% of amiodarone-treated patients. AIH is classified as type 1 or type 2. Type1 AIH occurs in patients with underlying thyroid condition while Type2 AIH is a result of amiodarone causing a subacute thyroiditis. Appropriate therapy for amiodarone-induced hyperthyroidism requires a careful diagnosis that may be difficult to achieve.<p ...

BackgroundFaced with the increase in the number of diabetic patients in Tunisia, an inventory of their needs as well as their expectations is necessary to help the medical staff deliver appropriate means of therapeutic education of the patient.AimWe aim to assess Tunisian diabetic patients’ understanding of the disease, evaluate its impact on several aspects of their life, and classify their needs and ex...

IntroductionHypopituitarism is the partial or complete loss of anterior pituitary function that can result from acquired or congenital causes. Understanding its clinical aspects in children could lead to early diagnosis and therefore better outcome.ObjectiveThe aim of this study is to evaluate the characteristics of presentation, and etiology of Hypopituitarism in children.Methods<p...

IntroductionPsychogenic polydipsia (PPD), also known as self-induced water intoxication, is mostly seen in psychiatric populations. PPD can lead to life threatening complications and may even be lethal if not diagnosed and treated early. The aim of this study is to determine the clinical and biological features of PPD.Patients and methodsA retrospective study including 11 patients consulting for polydipsia at...

Introduction: Advances in diagnosis and treatment over the years have improved the life expectancy and quality of life for individuals with congenital adrenal hyperplasia (CAH). The inevitable alteration of the hypercortisolism-hyperandrogenism balance with current CAH therapy could be responsible for several anomalies in the gonadotropic axis and compromise fertility. This study aims to investigate this aspect in an aging Tunisian population of patients with CAH.<p class=...

Introduction: Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder affecting adrenal steroid synthesis. Its treatment aims to achieve a balance between optimal glucocorticoid replacement and normal androgen levels. The long-term outcomes of this condition are poorly studied. The objective of this study is to evaluate the impact of CAH due to 21-hydroxylase deficiency on final height (FH), bone metabolism, and cardiometabolic risk in a Tunisian cohort.<p ...