Searchable abstracts of presentations at key conferences in endocrinology

ea0016p185 | Diabetes and cardiovascular diseases | ECE2008

Metabolic improvement in diabetic patients under education before implantation of the insulin sibcutaneous continuous infusion (ISCI)

Maraver Silvia , Martinez de Pinillos Guillermo , Morales Cristobal , Garcia-Quiros Juan Manuel , Tome Monica , Serrano Isabel , Garcia Teresa , Cuesta Carmen , Sendon Angel

Introduction: ISCI treatment is useful to optimize treatment in patients with DM1. Before implantation, is necessary the education of patients, as in technical aspects so in the handling of diabetes with this therapy.Objective: Evaluate the results of the diabetological education previous to the implantation of the ISCI and the repercussion of this program in patients metabolic control.Material and method: Forty-seven diabetic pati...

ea0016p414 | Neuroendocrinology | ECE2008

Autoimmune hypophysitis and isolated corticotrophin deficiency

Gentil Alfonso , Martin Tomas , Torres Alberto , Serrano Isabel , Morales Cristobal , Maraver Silvia , Martinez de Pinillos Guiillermo , Garcia-Quiros Juan Manuel , Sendon Angel

Introduction: Isolated ACTH failure is a rare disorder characterized by a secondary adrenal failure and a considerable deterioration of the general state. In adults the has been established related to cranial traumatism and to autoimmune hypophysitis (AH). It has been pointed out that the isolated failure of pituitary tropin in the context of a AH, could end with a global pituitary failure.Objective: Evaluation of the shortage of isolated ACTH as a way o...

ea0016p726 | Thyroid | ECE2008

Surgical management of amiodarone-associated thyrotoxicosis

Maraver Silvia , Serrano Isabel , Morales Cristobal , Martinez de Pinillos Guillermo , Garcia-Quiros Juan Manuel , Tome Monica , Jimenez-Garcia Antonio , Sendon Angel

Introduction: Amiodarone is an excellent antiarrhythmic with a high use although it isn’t free from complications. Most of patients stay euthyroid (80%), inducing thyroid dysfunction in the remaining 20% (thyrotoxicosis, 1.5–3%).Objective: We analyze amiodarona-associated hyperthyroidism surgical management according to the associated pathology and patients clinical evolution.Subjects and methods: We report four patients ...

ea0016p729 | Thyroid | ECE2008

Valuation of iodine deficiency in Western Andalusia by means of the neonatal screening of congenital hypothyroidism

Garcia-Quiros Juan Manuel , Morales Cristobal , Maraver Silvia , Martinez de Pinillos Guillermo , Tome Monica , Cuesta Carmen , Guerrero J M , Sendon Angel

Introduction: The accomplishment of screening neonatal congenital hypothyroidism allows the use of the determination of TSH in new born (NB) like indirect marker of the iodine ingestion of the pregnant woman and the nutritional iodine deficiency in the population. In populations with a sufficient iodine ingestion, the proportion of children with TSH superior to 5 U/ml is smaller of 3%.Primary target: To make the iodine deficiency map in the studied area ...

ea0014p511 | (1) | ECE2007

Pheochromocytoma in pediatric age

Fernández-Argüelles García Amaya , Morales Portillo Cristóbal , Campos Martín Cristina , Espino Rafael , López-Canti Luis

Introduction: Pheocrhomocytomas are rare tumors, principally benigns, and with high risk of morbimortality because of secretion of big amountos of catecholamines. They are an unfrequently cause of arterial hypertension in pediatric age but physicians must remember it because they can be diagnosed, treated and cured in a proper way.Objectives: To evalue the cases reports of pediatric pheochromocytoma found in our area, to analyze the differences in diagno...

ea0056p164 | Bone ' Osteoporosis | ECE2018

Influence of the levels of vitamin D on T-score in HIP measured by DXA of colombian postmenopausal women

Buendia Richard , Cardenas Santiago , Zambrano Monica , Buendia Andres , Varon Maria De Los Angeles , Mier Heidy Carolina , Morales Alejandra , Alejo Adriana , Sanchez Diego

Introduction: The 25hydroxyvitamin(OH)D deficiency has been linked to the risk of postmenopausal fractures and osteoporosis. In Colombia,the prevalence of 25(OH)vitaminD deficiency is high, reaching more than 53% of the total population. It can be stated that hip fracture is one of its most feared complications, with a high risk of mortality and morbidity,which can affect even osteopenic patients. The objective of this study is to assess modifications in hip T-score (using dua...

ea0056p499 | Diabetes therapy | ECE2018

Metabolic effects of liraglutide in type 2 diabetic patients.

Muros Mariola Mendez , Portillo Cristobal Morales , Hermosilla Antonio Manuel Garrido , Septimo Vianney Magaly Santiago , Perez Antonio Perez , Margalet Victor Sanchez , Brocca Maria Asuncion Martinez

Objectives: Obesity and type 2 diabetes mellitus (DM2) are risk factors for non-alcoholic fatty liver disease (NAFLD). The main objective was to study the incidence of NAFLD using the Hepatic Steatosis Index (HSI) in obese patients with DM2. Secondary objectives were to analyse the effect of liraglutide over HSI, body mass index (BMI) and glycated hemoglobin (HbA1c).Methods: Retrospective observational study of obese type 2 diabetic patients treated with...

ea0056p1048 | Thyroid (non-cancer) | ECE2018

Correlation of recommended diagnostic tools with pathological findings in the thyrotoxic patient

Perdomo Carolina M , Paricio Jose Joaquin , Llavero Maria , Gargallo Javier , Garcia Marta , Miralles Raquel , Morales Maria I , Alcalde Juan , Idoate Miguel Angel , Arbizu Javier , Galofre Juan C

Aim: A key diagnostic step to determine the cause of hyperthyroidism is the measurement of circulating thyroid-stimulating immunoglobulin (TSI). High levels are associated with Graves’ disease (GD). A thyroid scintigraphy (TRS) is recommended when TSI is absent or its measurement unavailable, as TRS is capable of differentiating between GD (diffuse uptake) and toxic goitre (TG) (patchy uptake). Nevertheless, and while rarely necessary, histopathology remain the best metho...

ea0101ps2-12-06 | Diagnosis of thyroid cancer-1 | ETA2024

A comparative study between the old and the new version of a microrna and dna-based molecular classifier for indeterminate thyroid nodules in real-world samples

Santos Marcos , Felix de Oliveira Andrei , de Oliveira Miriane , Frizzo Rabelo Bruna , Gatti Deo Thamiris , Nogueira Vilela Diego , Mari Fredi Bruno , Fernanda Morales Augusto Isabela , Moretto Rodrigues Bruna

Background: In 2018 we presented the first version (v1) of our microRNA-based algorithm for indeterminate thyroid nodules classification (mir-THYpe full), which was used in real-world clinical routine until recently, when an new optimized version (v2) was released using new machine learning techniques and combinating microRNA and DNA data.Objective: Our aim was to simulate and analyze what the performance of v2 algorithm would have been, if it had been u...

ea0101ps2-12-07 | Diagnosis of thyroid cancer-1 | ETA2024

Molecular profiling of thyroid nodules: insights from the mir-thype full trial in brazilian patients

Santos Marcos , Moretto Rodrigues Bruna , de Oliveira Andrei , Nogueira Vilela Diego , de Oliveira Miriane , Rabelo Bruna , Gatti Deo Thamiris , Mari Fredi Bruno , Fernanda Morales Augusto Isabela

Background: Thyroid nodules are prevalent in up to 60% of the adult population, occurring in a ratio of 4:1 woman/man. Using fine needle aspiration, approximately 25-30% of cases are categorized as "indeterminate": Bethesda 3 (B3) or Bethesda 4 (B4). In these cases, molecular tests, such as mir-THYpe full, can assist in diagnosis and prognosis, utilizing microRNA profiling and DNA analysis of mutations including BRAF V600E, pTERT C228T/C250T, RET M918T, C634Y/R, and V8...