Searchable abstracts of presentations at key conferences in endocrinology

ea0073aep563 | Pituitary and Neuroendocrinology | ECE2021

Invasive Thyrotropin-secreting pituitary adenoma: A case report

Wiem Madhi , Jemel Manel , Said Wadiaa , Mereghni Syrine , Allah Chatti Hiba , Kandara Hajer , Kammoun Ines

IntroductionThyrotropin-secreting pituitary adenoma is a rare cause of hyperthyroidism which must be differentiated from other etiologies of inappropriate TSH secretion.Observation:We report the case of a 49 years old male patient with no particular pathological history, addressed for thyrotoxicosis (weight loss, irritability, thermophobia, dyspnea and palpitation) with no goiter or ophtalmopathy. Echocardiog...

ea0073aep579 | Reproductive and Developmental Endocrinology | ECE2021

Congenital GH deficiency in children: What are the differences between isolated and combined/total and partial somatotropic GH deficiency?

Dorraelguiche Dorra , Jemel Manel , Anis Grassa , Gharbi Radhouane , Kandara Hajer , Kammoun Ines

Introduction Growth hormone (GH ) deficiency is a rare but not exceptional cause of statural delay in children. The results of GH stimulation tests and the exploration of other pituitary axes allow us to conclude on the nature of the deficiency: total or partial and its possible association with other pituitary deficits.MethodsThis is a retrospective descriptive study including 75 patients followed for congen...

ea0073aep709 | Thyroid | ECE2021

Antithyroid drugs as treatment of neutropenia in hyperthyroidism

Essayeh Sawsen , Jemel Manel , Chatti Hiba , Madhi Wiem , Gharbi Radhouane , Kandara Hajer , Kammoun Ines

IntroductionHematological abnormalities are frequently observed in hyperthyroidism and are part of complex, multifactorial pathogenetic mechanisms that are still poorly understood, which can affect the three hematopoietic lineages in isolation or in combination. For the endocrinologist, they raise the issue of the risk of their aggravation under the hamatotoxic effect of antithyroid drugs (ATDs).Case presentation<p class="abste...

ea0073aep863 | Late Breaking | ECE2021

Predictive factors of final height in children with congenital growth hormone deficiency in Tunisian children

Dorraelguiche Dorra , Jemel Manel , Grassa Anis , Gharbi Radhouane , Kandara Hajer , Kammoun Ines

IntroductionGrowth hormone deficiency (GHD) is a rare cause of statural retardation in children. The diagnosis is evoked in front of a bundle of anamnestic, clinical and radiological arguments. Treatment consists of substitution by recombinant GH with the aim of restoring normal size. There is interindividual variability in the response to treatment. We therefore proposed to study the response to treatment as well as the predictive factors of this respon...

ea0073aep864 | Late Breaking | ECE2021

Are there a gender difference in growth hormone (GH)-deficiency in Tunisian Children?

Dorraelguiche Dorra , Jemel Manel , Anis Grassa , Gharbi Radhouane , Kandara Hajer , Kammoun Ines

IntroductionCongenital GH deficiency is more common in boys than in girls. Several differences have been noted between the 2 genders. We proposed to study these differences for epidemiological, auxological and anthropometric characteristics.MethodsThis is a retrospective study including 75 patients followed for congenital GH deficiency in the endocrinology department at the National Institute of Nutrition in ...

ea0099p67 | Diabetes, Obesity, Metabolism and Nutrition | ECE2024

Prevalence and predictive factors of sleep apnoea in type 2 diabetic patients

Adel Meriem , Ben mohamed Rayene , Chiboub Marwa , Ghram Lina , Kandara Hajer , Jemel Manel , Kammoun Ines

Introduction: Obstructive sleep apnoea (OSA) is common in people with type 2 diabetes mellitus (T2DM), with prevalence ranging from 20-50% and up to 85% in obese T2DM. However, OSA remains largely undiagnosed due to the high cost of testing and limited availability of sleep clinics, particularly in developing countries. The aim of this study is to determine the prevalence of type 2 diabetic patients at high risk of OSA and to identify factors associated with OSA in this popula...

ea0099p296 | Diabetes, Obesity, Metabolism and Nutrition | ECE2024

Unveiling connections: type 2 diabetes, male hypogonadism, and inflammation –insights from a clinical study

Grassa Anis , Jemel Manel , Salhi Salma , Krir Asma , Benhmid Ahlem , Chiboub Marwa , Gharbi Radhouane , Kammoun Ines

Introduction: The interplay between type 2 diabetes (T2D), male hypogonadism (HG), and inflammation has emerged as a fascinating area of medical research. Understanding the complex relationship among these factors is crucial for advancing our knowledge.Methods: The study focused on 250 adult male patients with T2D recruited from outpatient clinics at the National Institute of Nutrition and Food Technology. A thorough assessment of gonadal hormones, inclu...

ea0099p493 | Diabetes, Obesity, Metabolism and Nutrition | ECE2024

Sleep apnoea and degenerative complications in type 2 diabetes

Adel Meriem , Ben mohamed Rayene , Chiboub Marwa , Ghram Lina , Kandara Hajer , Jemel Manel , Kammoun Ines

Introduction: Obstructive sleep apnoea (OSA) is notably prevalent in individuals with type 2 diabetes (T2D). This syndrome not only elevates cardiovascular risk but is also implicated in the advancement and exacerbation of microangiopathy. The objective of our study was to evaluate the prevalence of diabetic complications in patients with type 2 diabetes who have OSA.Method: A cross-sectional study was conducted on 130 patients with DT2 who were hospital...

ea0099ep951 | Diabetes, Obesity, Metabolism and Nutrition | ECE2024

Hypogonadism in men with type 2 diabetes: a close look at anthropometric insights

Grassa Anis , Jemel Manel , Salhi Salma , Khalfa Brahim , Chiboub Marwa , Talbi Emna , Kandara Hager , Kammoun Ines

Introduction: Obesity and hypogonadism (HG) are two conditions frequently observed in people with type 2 diabetes (T2D). The complex relationship between obesity and hormonal imbalances, particularly hypogonadism, remains a key area of interest in understanding the overall health profile of men with T2D.Methods: In this cross-sectional study involving 250 men with T2D undergoing diabetes consultations, comprehensive clinical examinations were carried out...

ea0099ep470 | Pituitary and Neuroendocrinology | ECE2024

Infundibuloneurohypophysitis in sjögren’s syndrome: a case report

Terzi Ameni , Manel Jemel , Cyrine Chehaider , Meriem Adel , Marwa Chiboub , Hajer Kandara , Ines Kammoun

Introduction: Infundibuloneurohypophysitis (INH) is an autoimmune disease that typically presents as central diabetes insipidus (CDI). It is often more common in women with an autoimmune background. Here, we have the opportunity to describe an unusual case of a female patient who developed SjögrenÂ’ syndrome (SJS) following CDI.Case presentation: A 55-year-old female was admitted to our department for exploration of polyuoropolydipsic syndrome e...