Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep186 | Reproduction, endocrine disruptors and signalling | ECE2015

Relationship between polycystic ovary syndrome and platelet distribution width

Yilmaz Ozgur , Temur Muzaffer , Calan Mehmet , Ozbay Elif Pelin Ozun , Karakulak Murat , Kume Tuncay

Purpose: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive period, and it has been considered as a risk factor in cardiovascular disease due to increased prevalence of hypertension, dyslipidaemia, obesity, and insulin resistance. Platelets have a pivotal role in the development of atherothrombosis. Platelet distribution width (PDW) is a marker of platelet size that reflects the heterogeneity of the platelets. This arithmetical inde...

ea0037ep416 | Diabetes (complications & therapy) | ECE2015

Comparison of umbilical cord ghrelin concentrations in full-term pregnant women with or without gestational diabetes

Karakulak Murat , Saygili Ugur , Temur Muzaffer , Yilmaz Ozgur , Ozbay Elif Pelin Ozun , Calan Mehmet , Cosar Hese

Purpose: The purpose of this study was to analyse ghrelin concentrations in the umbilical cord of pregnant women with a diagnosis of gestational diabetes mellitus. The relationship between ghrelin concentrations and birth weights was investigated.Materials and methods: Sixty pregnant women with gestational diabetes mellitus and 64 healthy pregnant women with three oral glucose tolerance test results within normal limits were included in the study. Follow...

ea0037ep489 | Diabetes (complications & therapy) | ECE2015

Insulin oedema in newly diagnosed type 1 diabetes patient: a case report

Oguz Ayten , Tuzun Dilek , Sahin Murat , Atay Didem , Ganidagli Berivan , Ganidagli Safa Ersen , Gul Kamile

Aim: In this case report we present a newly diagnosed, underweight type 1 diabetes mellitus (DM) patient developed insulin oedema following high dose insulin therapy.Case: A 18-year-old male patient was admitted to the hospital with a 1-month history of excessive water consumption, pollakiuria, polyuria, and weight loss 6 kg. In laboratory examination, hyperglycaemia and ketonuria were detected; arterial blood pH was 7.38. Patient was hospitalised to the...

ea0037ep582 | Obesity and cardiovascular endocrinology | ECE2015

Neutrophil to lymphocyte ratio as an inflammatory marker in obesity

Soysal-Atile Neslihan , Ekiz-Bilir Betul , Bilir Bulent , Baykiz Derya , Topcu Birol , Aydin Murat

Aim: Cardiovascular morbidity and mortality of obesity is associated with classic risk factors, namely dyslipidaemia, hypertension and impaired glucose metabolism. Aim of this study is to evaluate inflammation as an independent risk factor by using neutrophil to lymphocyte ratio (NLR).Materials and methods: Patients who admitted to our outpatient clinic between January and December 2014 were assessed retrospectively. Patients diagnosed as diabetes, predi...

ea0037ep1011 | Thyroid (non-cancer) | ECE2015

Correlation of midkine levels in serum and thyroid nodules with histopathological, haematological and radiological variables

Kuzu Fatih , Arpaci Dilek , Altas Ayfer , Haytaoglu Gurkan , Can Murat , Barut Figen , Bayraktaroglu Taner

Aim: To evaluate serum (SMK) and nodular (NMK) midkine levels in thyroid nodules and explore its relevance to ultrasound feature/pathological results.Methods: A total of 80 patients (56 women, 24 men) with thyroid nodules were included in this prospective study. Hemograms, thyroid function tests, fine needle aspiration biopsies, ultrasonographic evaluation were routinely made. In addition, levels of SMK and NMK were measured. Any possible correlations be...

ea0037ep1063 | Thyroid (non-cancer) | ECE2015

The effect of vitamin D on thyroid autoimmunity

Simsek Yasin , Cakir Ilkay , Kucukler Ferit Kerim , Diri Halit , Baglicakoglu Murat , Guler Serdar

Introduction: Although, vitamin D (vit D) mainly regulates calcium and phosphate metabolisms, its deficiency may also contribute to the development of some carcinomas, autoimmune, and cardiac diseases. Vit D deficiency has been defined to correlate with increased autoimmune disease such as type 1 diabetes mellitus, rheumatoid arthritis, autoimmune thyroid diseases (AITD). Previous studies suggested that patients with AITD had lower vit D levels when compared with healthy contr...

ea0037ep1106 | Endocrine tumours | ECE2015

Relationship between thrombotic markers, insulin resistance and thyroid volume in women with prolactinoma

Oguz Ayten , Tuzun Dilek , Sahin Murat , Inanc Elif , Gokalp Irem , Atay Didem , Demir Hakan , Gul Kamile

Aim: Hyperinsulinaemia is frequent finding in patients with hyperprolactinemia and has associations with thyroid volume. In this study, we evaluated the association between thrombotic markers, insulin resistance, CIMT, and thyroid volume in female patients with prolactinoma.Material and methods: 38 women with prolactinoma and 24 healthy women were included to the study. We evaluated anthropometric, biochemical, hematologic and hormonal parameters as well...

ea0037ep1210 | Clinical Cases–Pituitary/Adrenal | ECE2015

A case of pleomorphic adenoma and acromegaly: a coincidence or a pathophysiological association?

Topaloglu Oya , Polat Sefika Burcak , Ozturk Cemaleddin , Bavbek Murat , Muderris Togay , Ersoy Reyhan , Cakir Bekir

Introduction: Acromegaly is a chronic disease caused by excessive secretion of growth hormone (GH), and as a result, of insulin-like growth factor-1 (IGF1). Although controversial, frequency of both benign and malignant neoplasm formation is thought to be increased in acromegalic patients. Pleomorphic adenoma is the most common arising tumour from the parotid salivary gland. Here we report the case of a 33-year-old woman with acromegaly and also who presented with a swelling o...

ea0035p31 | Adrenal cortex | ECE2014

Postpartum adrenocortical deficiency: a case report

Bayraktaroglu Taner , Kuzu Fatih , Tikanak Sevval Peynir , Acar Fatma Zor , Can Murat

Introduction: We report a case with primary adrenocortical deficiency after the first month of lactation.Case report: Thirty-year-old woman was referred with complaints including dizziness, weakness and fatigue in the early postpartum and lactation period. On physical examination, weight 63 kg, height 164 cm, blood pressure 100/65 mmHg, pulse 96 per min were detected. She had the increase of the brown pigmentation on her hands and face. In the a...

ea0035p146 | Calcium and Vitamin D metabolism | ECE2014

Three patients with idiopathic hypoparatiroidism presented with different clinical manifestations

Gul Kamile , Sahin Murat , Oguz Ayten , Cabioglu Eren , Erhan Cigdem , Kesici Fatma , Ozkaya Mesut

Aim: Patients with hypoparatiroidism may admit to hospitals with different symptoms.In this report we presented 3 case of hypoparatiroidism with congestive heart failure,epilepsy and muscle pain.Case 1: 31-year-old male admitted to hospital with dyspnea on lying down and evaluation revealed pericardial and pleural effusion. The patient was hospitalized to cardiology clinic with a prediagnosis of decompansated heart failure. In echocardiography ejection f...