Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep780 | Endocrine Disruptors | ECE2017

Association of autoimmune endocrinopathies and celiac disease

Soumaya Mrabet , Imen Akkari , Taieb Ach , Koussay Ach , Elhem Ben Jazia

Introduction: Celiac disease (CD) is an immune-mediated small intestinal disorder that occurs in genetically susceptible people. It is significantly associated with other autoimmune disorders represented mainly by type 1 diabetes and autoimmune dysthyroidism.Material and methods: We report 23 observations of patients with autoimmune endocrinopathies associated with celiac disease.Results: There are 23 patients with an average age o...

ea0063p1137 | Reproductive Endocrinology 2 | ECE2019

Clinical and para-clinical characteristics of Klinefelter syndrome diagnosed in adulthood

Khaldi Safa , Hasni Yosra , Sarra Dimassi , Ach Koussay , Saad Ali

Klinefelter syndrome (KS) is the most frequent sex chromosomal disorder and affects approximately one in 660 newborn boys. The phenotype is variable ranging from ‘nearnormal’ to a significantly affected individual. Typically, diagnosis is delayed with the majority of patients identified during fertility workup in adulthood, and only 10% of patients diagnosed prior to puberty.Patients and methods: This is an 8-year retrospective study of the cli...

ea0081ep653 | Pituitary and Neuroendocrinology | ECE2022

The impact of Sheehan Syndrome on bone mineral density

Salah Ameni , Maaroufi Amel , Ajili Rihab , Saad Ghada , Hasni Yosra , Ach Koussay

Introduction: Sheehan syndrome (SS), or postpartum pituitary necrosis, is a complete or dissociated adeno-pituitary insufficiency due to hypovolemia secondary to excessive blood loss during or after delivery. Although few studies have investigated osteoporosis in isolated hormone deficiencies, the relationship between SS and osteoporosis has not been investigated in large series of SS. In this study, we aimed to evaluate bone mineral density (BMD) in patients with SS.<p cl...

ea0081ep723 | Pituitary and Neuroendocrinology | ECE2022

Digestive complications of acromegaly : about 40 cases

Rihab Ajili , Ameni Salah , Yosra Hasni , Baha Zantour , Habib Sfar , Koussay Ach

Introduction: Acromegaly is a rare hormonal condition that results from an excess amount of growth hormone (GH) in the body. A variety of complications have been reported in patients with acromegaly including cardiovascular diseases, diabetes mellitus or respiratory disorders. In addition, Acromegaly is associated with gastrointestinal complications. The aim of this study was to evaluate gastrointestinal complications and their impact on the quality of life among patients suff...

ea0081ep725 | Pituitary and Neuroendocrinology | ECE2022

Decreased quality of life in adult patients with sheehan syndrome

Salah Ameni , Maaroufi Amel , Ajili Rihab , Saad Ghada , Hasni Yosra , Ach Koussay

Introduction: Sheehan Syndrome (SS) is the oldest known cause of non-tumor acquired anterior pituitary insufficiency in women. The incidence of SS would probably have decreased in recent decades in developed countries thanks to the development of obstetric care. However, it still remains a public health problem in developing countries. In addition, it constitutes a chronic disabling pathology and is strongly linked to an alteration of the quality of life. In this study we aime...

ea0081ep822 | Pituitary and Neuroendocrinology | ECE2022

Sheehan Syndrome effects on cardiovascular risk

Salah Ameni , Maaroufi Amel , Ajili Rihab , Benabdelkarim Asma , Njah Maha Kacem , Hasni Yosra , Ach Koussay

Introduction: Sheehan syndrome has been for a long time the most frequent cause of hypopituitarism among women in developing countries, including Tunisia. Apart from hormonal deficits caused by SS, young women with SS are exposed to an increased risk of cardiovascular mortality. In this study, we aimed to evaluate the cardiovascular risk in patients with SS. Patients and methods This is a descriptive cross-sectional study. It was carried out in the Endocrinology department of ...

ea0063p368 | Thyroid 1 | ECE2019

Glucocorticoid Functional Reserve in Hashimoto Hypothyroidism before and after LT4 replacement

Taieb Ach , Abdelkarim Asma Ben , Yosra Hasni , Amel Maaroufi , Maha Kacem , Molka Chaieb , Koussay Ach

Introduction: It has been generally accepted that adrenal function might be impaired in patients with primary hypothyroidism. A transitory low glucocorticoid production has been identified in cases with severe hypothyroidism. We tried to evaluate adrenocortical glucocorticoid function using the low-dose Synacthen test, in patients with primary hypothyroidism. The primary endpoint was to contrast the cortisol response to low-dose Synacthen before L-T4 replacement and after norm...

ea0063p778 | Thyroid 2 | ECE2019

Graves’ disease: woman or man, is there a difference in clinical presentation or evolution?

Chermiti Sondes , Hasni Yosra , Bayar Ines , Abdelkarim Asma , Kacem Maha , Chaieb Molka , Maaroufi Amel , Ach Koussay

Grave’s disease (GD), like all autoimmune diseases, is predominantly female, with sex ratio to 3 women for one man. The treatment of first intension is based on antithyroid drugs (ATD). Our objective is to compare the clinical presentation and the evolution of GD by gender. It’s a retrospective study. We studied patients with a first diagnosis of GD, in the department of endocrinology in Farhat Hached hospital in Susah, between Juanuary 2010 and December 2015. The pa...

ea0063p967 | Diabetes, Obesity and Metabolism 3 | ECE2019

Assessment of the educational level of diabetics regarding their foot

Elfekih Hamza , Amor Bilel Ben , Hasni Yosra , Maaroufi Amel , Khochtali Ines , Ach Koussay

Introduction: Diabetic foot is known to represent a serious complication of diabetes mellitus, responsible for significant morbidity, disability and considerable financial implications. The prevention of this complication requires, first and foremost, a good patient education.Objective: To evaluate the current state of knowledge and practices of foot care in diabetic patients and to identify factors associated with a good educational level.<p class="...

ea0049ep441 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

Diabetic nephropathy in type 1 diabetes mellitus

Barka Ines , Chikhrouhou Nesrine , Maaroufi Amel , Kacem Maha , Chaieb Molka , Ach Koussay

Nephropathy is a serious complication of Type 1 diabetes mellitus (T1DM) with a grave prognosis after the onset of proteinuria. End stage of renal disease remains the major cause of excess morbidity and premature mortality in patients with T1DM. The aims of the present study were to investigate the prevalence of diabetic nephropathy and to evaluate risk factors for its development among patients developing T1 DM. Seventy six patients with T1DM history over 20 years were includ...