Endocrine Abstracts

Primary Carcinoid tumour of Epididymis is a very rare presentation. It accounts to only 0.23% of Carcinoid tumours. Here we present a patient with Primary Carcinoid tumour of Epididymis, which was successfully resected.A 57 year old gentleman with no significant past medical history was seen with painless swelling of his Right testes. He had no symptoms such as weight loss, Diarrhoea or flushing on direct questioning. Examination revealed a Solid, non-te...

Lipodystrophy is a rare disease characterized by generalized or partial lack of adipose tissue. Lipodystrophy is associated with leptin deficiency and leads to severe insulin resistance and metabolic abnormalities. A previous literature review reported an estimated prevalence of less than one in a million based on the assumption that only one-fourth of the patients with lipodystrophy may have been reported. Later, the prevalence of lipodystrophy was estimated through a search ...

Background: Isolated secondary hypothyroidism is rare. In the majority of cases the causes are genetic (gene mutations) or structural (mass effect or infiltration). Structural causes are usually associated with simultaneous deficiencies of other adenohypophyseal hormones. We present an identical twin with isolated secondary hypothyroidism.Case report: 1st Twin – 26-year-old obese lady, of Afro-carribean origin, presented with tiredness, weigh...

Background: Old age is proven to be one of the greatest danger factors for intensively dealing with COVID-19 patients. Stoutness and diabetes are enhancers of dangers among COVID-19 patients. In any case, there exists restricted proof for the modifiable danger components, for example, bodyweight which is an indicator of the Intensive Care Unit and its need among type 2 diabetes patients. In this review, the subject of body weight as an indicator of ICU confirmations will be in...

Introduction: Inferior petrosal sinus sampling (IPSS) is the gold standard test to differentiate Cushing’s disease from ectopic Cushing syndrome. IPSS may cause severe complications; however, overall rates are low. Subarachnoid hemorrhage (SAH) has been rarely reported after IPSS. Here we report a case who developed hypertensive emergency, left 6th cranial nerve palsy, and SAH after IPSS.Case: A sixty-two years-old female patient had a history of h...

Vitamin D binding protein (VDBP) has a critical role in orchestrating optimal vitamin D homeostasis and bioavailability. VDBP has been implicated in modulating the gene expression of amino-transporters within the placenta and might thus control the transfer of amino acids to neonates during in utero development. We hypothesize that dyshomeostasis of VDBP could lead to adverse metabolic profiles and low birth weight in neonates. VDBP genetic polymorphisms steer the uni...

Background: Despite global guidelines recommending initiation of SGLT2i drugs like dapagliflozin in type 2 diabetes (T2DM) patients with cardiovascular (CV) or renal risk, its clinical translation is still lacking in India.Objective: To understand clinicians’ perspectives regarding the association of CV risk and T2DM in Indian patients, and the need for the use of combination therapies with dapagliflozin in T2DM patients, in Indian clinical practice...

Introduction: In the modern day busy clinical practice the communication between patient and care giver is at minimal level. The patients feel apprehensive when advised about the surgical intervention. In such situation they feel the need of detail information from the care givers.Story telling is a tool which can be used for this problem. We intended to study the efficacy of storytelling technique on patients undergoing Hemithyroidectomy for benign cytology.<p class="abst...

Introduction: Hypokalemic periodic paralysis associated with hyperthyroidism is a well-known acute electrolyte and acute muscle disorder. Lesser known is normokalemic periodic paralysis associated with hyperthyroidism (TNPP). Because plasma potassium is normal, and it can be misdiagnosed as some other disorder if thyroid function is not evaluated. We report a case of TNPP due to non-autoimmune thyroiditis.Case report: A 23-year-old woman was admitted to ...

Dyslipidemiαs should be managed from childhood for prevention of early atheromatic vascular lesions and premature cardiovascular disease in adult life.Aim: We examined the frequency of different types of dyslipidemiα in children and the results on blood lipids of lifestyle intervention (diet and exercise).Patients and methods: We studied retrospectively 136 children, 74 boys and 62 girls, mean chronological age 8.5±3...