Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep135 | Clinical case reports - Pituitary/Adrenal | ECE2017

An association of adrenal ganglioneuroma, Addison’s disease and Mediterranean fever: a case report

Rkik Nabila , Mrabet Houcem , Elleuch Mouna , Ammar Mouna , Haj Kacem Faten , Abid Mohammed

Introduction: Ganglioneuroma is a rare benign tumour arising from neural crest sympathogonia. It is usually asymptomatic and non functional. An association between ganglioeneuroma and genetic or autoimmune diseases such as Addison’s disease or Mediterranean fever has never been described.Case description: We report the case of a 24-year-old woman presenting with paroxysmal abdominal pain with loss of weight and no fever. Physical examination along w...

ea0056p524 | Endocrine Nursing | ECE2018

Evaluation of the technique of insulin injection Analogue in Tunisia in diabetic type 2 and impact on the glycemic balance: study 56 cases

Boulbaba Boulbaba , Abdallah Rihab Ben , Elleuch Mouna , Ammar Mouna , Charfi Nadia , Abid Mohamed

Introduction: In Tunisia, only about 10% of people with diabetes practice self-injecting insulin analogues. It is 1 Tunisian adult out of 11 who is affected directly by diabetes. Our goal is to assess diabetes patients’ knowledge of insulin injection techniques.Patients and methods: Prospective study of 56 cases of type 2 diabetic patients in the Endocrinology Department CHU Hedi Chaker Sfax Tunisia. All patients had a questionnaire and clinical exa...

ea0049ep1128 | Female Reproduction | ECE2017

Secondary amenorrhea after bone marrow transplantation and adjuvant chemotherapy misdiagnosed as disorder of sex development: a case report

Elleuch Mouna , Ammar Mouna , Kacem Faten Hadj , Ghorbel Dorra , Rekik Nabila , Charfi Nadia , Kalthoum Mahdi , Mnif Mouna , Abid Mohamed

Introduction: Disorders of sex development (DSD) is a congenital condition in which the development of chromosomal, gonadal or genital sex is atypical. A female appearance patient with secondary amenorrhea and 46 XY karyotype seems to be solid evidences to diagnose Y-chromosome-related DSD diseases, while it is not necessarily the accurate diagnosis. We here report a case of a 16- year-old girl with secondary amenorrhea and 46 XY karyotype after bone marrow transplantation (BM...

ea0037ep1239 | Clinical Cases–Pituitary/Adrenal | ECE2015

A cystic lesion of the adrenal gland mimicking hydatid cyst

Kacem Faten Hadj , Ammar Mouna , Maalej Ayman , Cheikrouhou Nesrine , Charfi Nadia , Abid Mohamed

Introduction: Adrenal cystic lesions are uncommon and mostly identified incidentally during radiological investigations or at surgery for unrelated reasons. Its incidence varies between 0.064 and 0.18%. Adrenal cysts are classified as endothelial cysts, pseudocysts, epithelial cysts, and parasitic cysts.Case report: A 45-year-old female with a past medical history of systemic hypertensive disease for 2 years, presented with recurrent abdominal pain durin...

ea0056p941 | Female Reproduction | ECE2018

Acute and delayed responses of steroidal hormones after a resistance training session: time-of-day effects.

Naifar Manel , Turki Mouna , Ammar Achraf , Kacem Faten Haj , Abid Mohamed , Ayedi Fatma

The present study aimed to investigate the effect of time-of-days (TOD) on some biochemical and hormonal responses after resistance training sessions.Methods: Ten trained subjects performed three resistance-training-sessions at 0700 h, 1300 h and 1700 h. Each training-session included six upper and lower body resistance exercises with 3×10 repetitions. Blood lactate (Lac), creatine kinase (CK), lactate dehydrogenase (LDH), cortisol (C) and testoster...

ea0056p1025 | Thyroid (non-cancer) | ECE2018

Rare association of primary hyperparathyroidism and toxic multinodular goiter

Elfekih Hamza , Elleuch Mouna , Ghorbel Dorra , Hadjkacem Faten , Ammar Mouna , Kalthoum Mahdi , Charfi Nadia , Abid Mohamed

Introduction: The association of primary hyperparathyroidism (PHPT) and hyperthyroidism secondary to toxic multinodular goiter (TMNG) is rarely described in the literature. Hereby, we describe the clinical, biological, and radiological characteristics of two patients having this rare association.Observations: First case: A 66 years-old female was diagnosed with primary hyperthyroidism. Her thyroid antibodies were negatives. During the follow-up, she pres...

ea0049ep66 | Adrenal cortex (to include Cushing's) | ECE2017

Primary hyperparathyroidism associated with Cushing syndrome and primary hyperaldosteronism

Mnif Fatma , Elfekih Hamza , Elleuch Mouna , Hadjkacem Faten , Ghorbel Dorra , Rekik Nabila , Ammar Mouna , Mnif Mouna , Abid Mohamed

Introduction: The simultaneous occurrence in the same patient of more than one endocrinological condition is rare and was described in the multiple endocrine neoplasia (MEN). Here, we report a patient with an unusual combination of primary-hyperparathyroidism, papillary thyroid microcarcinoma, primary-hyperaldosteronism and ACTH-independent Cushing’s syndrome.Case description: A 54-year-old women with a primary-hyperparathyroidism was admitted to ou...

ea0049ep77 | Adrenal cortex (to include Cushing's) | ECE2017

Malignant androgen-secreting adrenocortical carcinoma with adrenal insufficiency: a case report

Mnif Fatma , Kalthoum Mehdi , Elleuch Mona , Wajdi Saafi , Charfi Nadia , Ammar Mouna , Feki Hamza , Mnif Mona , Abid Mohamed

Adrenocortical carcinoma (ACC) is a rare malignancy, accounting for 0.02% of all annual cancer. The majority of these tumors are benign, non-functioning adenomas that are incidentally discovered on abdominal image studies. Others are functional adenomas secreting cortisol, aldosterone, or less commonly androgens or estrogens. Pure androgen-secreting adrenal tumors are very rare.Case report: A 34-year-old female patient presented with pain in the left upp...

ea0049ep167 | Endocrine tumours and neoplasia | ECE2017

Corticotroph deficiency in patients with insulinoma

Kacem Faten Hadj , Ammar Mouna , Elleuch Mouna , ghorbel Dorra , Abdallah Rihab Ben , Charfi Nadia , Sefi Wajdi , Mnif Mouna , Abid Mohamed

Introduction: The metabolic stressor, hypoglycemia, elicits integrated counterregulatory responses, including activation of the hypothalamic–pituitary–adrenal axis. However, it is suggested that recurring insulin-induced hypoglycemia can impair this counter-regulation. Here we report three cases of patients with isulinoma and corticotroph deficiency.Case reports: The first case, 38-year-old man was referred because of recurrent episode...

ea0049ep770 | Clinical case reports - Thyroid/Others | ECE2017

Myasthenia gravis associated with Graves’ disease and adrenal insufficiency

Elleuch Mouna , Elfekih Hamza , Hadjkacem Faten , Kalthoum Mahdi , Ammar Mouna , Rekik Nabila , Safi Wajdi , Mnif Mouna , Abid Mohamed

Introduction: Multiple autoimmune syndrome (MAS) is a rare condition, first described by Humbert and Dupond in 1988 and characterised by three or more autoimmune disorders in the same individual.Case description: Here we present a case of 14-year-old female patient diagnosed with ocular myasthenia gravis. The diagnosis of Graves’ disease was suspected on the basis of hyperthyroidism symptoms and confirmed by undetectable TSH level (<0.01 mUI/l) ...