Endocrine Abstracts

Introduction: Autism is a neurodevelopmental disorder (NDD). It manifests itself in early childhood, with varying degrees of impact on the child’s developmental spheres. Although the underlying mechanisms have yet to be elucidated, ASD is considered to be multifactorial, with both genetic and non-genetic risk factors. Is there an established link between diabetes and autism?Observation: This is a 16-year-old child with no maternal history of hypergl...

Background and Aims: The objective of our study is to evaluate the degenerative profile in diabetic patients and their glycemic controlMaterials and Methods: This analytical cross-sectional study for analytical purposes was conducted during the period from January 2022 to January 2023, within the department of endocrinology and metabolic diseases of the Military Hospital of Instruction Mohamed V of Rabat.Results: 215 patients were ...

Introduction: Hypercortisolism is considered to be a rare condition with an estimated incidence between 0.4 and 2.4 cases per million per year, typically manifests as the clinically and biochemically evident Cushing’s syndrome. However, a more subtle form, known as subclinical hypercortisolism (SH) or autonomous cortisol secretion (ACS), poses diagnostic challenges. It is defined as excessive cortisol secretion without the classic manifestations of clinically overt Cushin...

Introduction: Gastroparesis is one of the dysautonomic manifestations of diabetic disease, particularly type 1. Often unnoticed or undetected by the clinician, it can be at the heart of a permanent imbalance, giving rise to all the microvascular and macrovascular complications of dysglycemia. We report the case of a diabetic patient who, after diagnosis and treatment of gastroparesis, achieved spectacular glycemic control.Observation: This is a 20-year-o...

Introduction and importance: Pseudo-Cushing’s syndrome (PCS) encompasses a spectrum of medical conditions, both physiological and non-physiological, that replicate the clinical features of Cushing’s syndrome (CS). In PCS, there is a presence of mild biochemical hypercortisolaemia, which is carefully regulated by physiological feedback hormonal control mechanisms. Physiological conditions contributing to PCS include factors like pregnancy surgical or emotional stress,...

Introduction: Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a rare congenital cause of primary amenorrhea, characterized by aplasia of the vagina with or without concurrent uterine and/or cervical aplasia. MRKH syndrome has a heavy psychological impact, and requires multidisciplinary management.Case Report: A 17-year-old female patient presented for exploration of a primary amenorrhea. Her medical history was significant for recurrent urinary tr...

Background and aims: The objective of our study is to evaluate the respect of Muslim diabetics for the contraindication of fasting and the control metabolic impact of fasting during the month of Ramadan. Materials and methods: This analytical cross-sectional study was conducted during the period from Mars to June of the year 2021, within the department of endocrinology and metabolic diseases of the Military Hospital of Instruction Moham...

Introduction: We report a case of malignant hypercalcemia complicated by acute pancreatitis, in a patient whose cardiac insufficiency obliged us to use an unconventional therapeutic means: calcimimeticsCase Report: Mrs. Halima, 74 years old, had a history of arterial hypertension complicated by ischemic heart disease at the stage of heart failure. She consulted the emergency room for typical pancreatic pain, the biological workup found a lipasemia at 30 ...

Introduction: Refractory hypothyroidism is a fairly common situation in the practice of any endocrinologist, being defined by the persistence of hypothyroidism despite adequate doses of replacement therapy with Levothyroxine, generally supraphysiological. We report the case of refractory hypothyroidism under high doses of Levothyroxine.Observation: she was a 54-year-old woman, diabetic Type2, followed for 06 years for papillary carcinoma of the thyroid g...

Introduction: We report the case of a patient with corticotropic insufficiency associated with diabetes insipidus who presented to the emergency room with profound hyponatremia; a complicated situation, whose solution was hidden in the galenic form of Desmopressin.Case report: Mrs Y. Amina, 37 years old, has been followed for 10 years for a non Langerhansian histiocytosis of pituitary location, complicated by a corticotropic insufficiency under hydrocort...