Endocrine Abstracts

The effects of goitrogens on the thyroid gland have been much studied and calcium is considered as a goitrogen in some cases. Since the level of calcium is high in drinking water of some cities of Khuzestan province, the effects of high calcium intake on the function of thyroid gland is investigated in this study. For this purpose the concentration of thyroid hormones is measured in rats.The study was carried out on73 male and female rats. The animals we...

The effects of goitrogens on the thyroid gland have been much studied and calcium is considered as a goitrogen in some cases. Since the level of calcium is high in drinking water of some cities of Khuzestan province, the effects of high calcium intake on the function of thyroid gland is investigated in this study. For this purpose the concentration of thyroid hormones is measured in rats.The study was carried out on73 male and female rats. The animals we...

Aim: The research was conducted as a randomized controlled experimental study to determine the foot health status of individuals with type 2 diabetes and the factors affecting them, to use a protocol to protect and improve foot health for individuals with diabetes, and to determine the effects of this protocol on foot health problems (regarding dermatology, orthopedics, circulation, sensory, footwear and self-care skills), foot health knowledge and foot care behaviors.<p c...

Objective: To determine risk factor pattern of the metabolic syndrome (MetS) and its association with serum nitric oxide metabolites (NOx) in children and adolescents.Subjects and methods: A cross-sectional study was carried out in 409 male and 442 female children and adolescents aged 4 to 19 years. The ethical committee of our institute approved the study. The MetS was defined according to modified ATPIII criteria and factor analysis was used...

Introduction: Thyroid hormones have major effects on regulation of metabolism and function of most cells. A number of prevalent diseases during adulthood have been attributed to the intrauterine status during fetal life. In this study, the effect of fetal hypothyroidism on the carbohydrate metabolism during adulthood investigated.Subject and methods: After mating, the pregnant rats were divided in two, the fetal hypothyroidism (FH) and the control (C) gr...

Introduction: The islets of pancreas contain relatively high levels of Gamma-amino butyric acid (GABA). This study was designed to determine the role of the GABA and GABAB receptor on glucose-stimulated insulin secretion of isolated islets in rats.Materials and methods: The Collagenase digestion technique was used to isolate the islets from male Wistar rats and insulin secretion was assessed in islets exposed to glucose (8.3, 16.7 mM) in prese...

Background: Magnesium is the fourth most abundant action in the body and plays an important role in metabolic processes. Association between magnesium deficiency and clinical condition including hypertension, diabetes, insulin resistance, hyperlipidemia, and atherosclerosis. Although magnesium deficiency is associated with a variety of medical conditions, the prevalence of hypo- and hypermagnesemia have not been reported in general population.Methods: Th...

Introduction: Vitamin D deficiency is a common clinical finding in the general population and hospitalized patients, including patients in the intensive care unit(ICU). Acute kidney injury (AKI) occurs in more than 50% in ICU admitted patients.Objectives: Due to the fact that there are few studies about AKI in COVID-19 patients, we investigated the relationship between vitamin D3 deficiency and the occurrence of AKI in COVID-19 patients.<p class="abs...

Introduction: Any abnormalities during pregnancy can affect the growth and development of the fetus and may have a long lasting effect presented during adulthood (intrauterine programming). In this study, the effect of maternal hypothyroidism on insulin secretion from the isolated islets of offspring has been investigated in male rats.Materials and methods: In Test group maternal hypothyroidism was induced using 0.02% propylthiouracyl in drinking water t...

Introduction: Radioiodine-resistant thyroid carcinoma is an important milestone in the treatment and follow-up of thyroid cancers. The biological defects of iodine uptake in thyroid cancer cells should be well known. In this study, we aimed to evaluate the clinical and pathological features and SLC5A5 gene expression status of iodine-refractory papillary thyroid carcinoma patients. Material-Method: We studied SLC5A5 expression in 83 papillary thyroid car...