Searchable abstracts of presentations at key conferences in endocrinology

ea0081p467 | Thyroid | ECE2022

Vitamin D levels in patients with graves orbitopathy

Boutzios Georgios , Chatzi Sofia , Mina Areti , Koukoulioti Eleni , Tzioufas Athanasios

Introduction: Graves’ disease (GD) is an autoimmune thyroiditis frequently associated with development of Graves’ orbitopathy (GO). GD patients have lower vitamin D levels compared to the general population. Whether low vitamin D levels are associated with GO is still controversial. The aim of our study was to assess the vitamin D levels in patients with GO and the clinical outcome.Methods: This is a single-center observational study in an outp...

ea0044p114 | Diabetes and Cardiovascular | SFEBES2016

The impact of thyroid autoimmunity on insulin secretion in pre-diabetic patients with normal thyroid function

Alexandraki Krystallenia , Liatis Stavros , Kaltsas Gregory , Boutzios Georgios

Introduction: Autoimmune thyroid disease (AITD) and abnormal carbohydrate metabolism are the commonest endocrine disorders in the general population. However, the effect that AITD may exert in β-cell secretion and insulin action in patients pre-diabetes has not been investigated before.Methods/design: One hundred and eighty-two patients (157 females) 46.5±14.2 years with pre-diabetes (impaired fasting glucose (IFG) or/and impaired glucose toler...

ea0056p912 | Female Reproduction | ECE2018

Presence of antiphospholipid antibodies is associated with increased failure rates of assisted reproductive techniques: a meta-analysis

Boutzios Georgios , Papadimitriou Eirini , Mathioudakis Alexandros , Vlachoyiannopoulos Panayiotis , Mastorakos George

Introduction: The presence of antiphospholipid antibodies is associated pathogenically with thrombotic vascular events and resulting pregnancy complications. Studies support that antiphospholipid antibodies (aPL) impair female fertility by interfering with endometrial decidualization and implantation. This meta-analysis aims to determine the prevalence of aPL in women undergoing assisted reproductive techniques (ART) for in Vitro Fertilization and Embryo Transfer (IVF-ET)....

ea0099p379 | Thyroid | ECE2024

Autoimmune endocrinopathies in patients with relapsing and remitting multiple sclerosis

Chatzi Sofia , Georgakopoulou Vasiliki , Paschou Stavroula , Boutzios Georgios

Introduction: Patients with multiple sclerosis (MS) demonstrate, in a number of studies, increased risk of acquiring another autoimmune disease compared to general population. Autoimmune thyroid diseases, type 1 diabetes, psoriasis and inflammatory bowel disease are the most common reported. The aim of our study is to determine potential factors that affect the presence of autoimmune endocrinopathies in patient with relapsing and remitting MS.Methods: We...

ea0099ep1056 | Adrenal and Cardiovascular Endocrinology | ECE2024

Administration of high dose vitamin E in female rabbits with hypercholesterolemia increases acutely androgen levels: an animal model study

Vlachos Ioannis , Chatzi Sofia , Kontzoglou Konstantinos , Boutzios Georgios

Introduction: Only few studies were observed, supporting the hypothesis that the administration of high doses of vitamin E in people with elevated serum total cholesterol levels leads to increased adrenocortical hormone secretion. There are only limited data concerning androgen or estrogen levels. The aim of this study is to investigate the possible effect of Vitamin E on adrenal and sex hormones in rabbits with hypercholesterolemia, as an animal model for the research.<p ...

ea0099ep608 | Thyroid | ECE2024

Distant metastasis at the time of diagnosis in a young male patient with classical subtype of papillary thyroid carcinoma and graves’ disease

Chatzi Sofia , Tsourouflis Gerasimos , Koukoulioti Eleni , Boutzios Georgios

Introduction: Patients with Graves’ disease (GD) and thyroid nodules have an elevated risk of developing papillary thyroid carcinoma (PTC). Distant metastasis observed in 1-9% of patients with PTC. The classical subtype usually demonstrates favorable prognosis compared to other more aggressive PTC subtypes, for which an increased risk of extranodal metastases is observed.Aim of the Study: We present an unusual case of a young male diagnosed with cla...

ea0081p498 | Thyroid | ECE2022

Tocilizumab: an effective and low-cost treatment for recent-onset active moderate to severe graves orbitopathy. a case report

Boutzios Georgios , Chatzi Sofia , Karampela Athina , Goules Andreas , Tsourouflis Gerasimos , Tzioufas Athanasios

Introduction: Graves orbitopathy (GO) is an inflammatory condition of the orbital fat and muscles and affect 30-50% of patients with Graves’ disease. The first-line treatment of moderate to severe GO according to EUGOGO is intravenous glucocorticoids, but 20-30% of the cases appear to be corticosteroid resistant or refractory. Promising results have been described with Tocilizumab (TCZ) as a second-line moderate to severe GO treatment.Case presentat...

ea0081ep1040 | Thyroid | ECE2022

Risk factors for central neck lymph node metastasis in patients with macro and micropapillary thyroid carcinoma

Boutzios Georgios , Chatzi Sofia , Mina Areti , Koukoulioti Eleni , Giovannopoulos Ilias , Tsourouflis Gerasimos

Introduction: The prevalence of lymph node metastasis from micropapillary thyroid carcinoma (mPTC) in different studies is up to 33%. Preoperative diagnosis of central lymph node (CLN) metastasis is essential for the surgical management of those patients. Prophylactic CLN dissection for patients with mPTC is controversial. Our study aimed to assess the prevalence and the risk factors of LMN metastasis in patients mPTC Methods: We retrospectively study th...

ea0090p231 | Thyroid | ECE2023

Differences between Unilateral and Bilateral Graves’ Orbitopathy. An observational study

Boutzios Georgios , Chatzi Sofia , Mina Areti , Fanouraki Maria , Giovannopoulos Ilias , Karampela Athina , Goules Andreas , Tzioufas Athanasios

Introduction: Graves’ Orbitopathy (GO), the most common extrathyroidal manifestation of Graves’ disease (GD), usually presents bilateral disease. However, a minority of patients present with unilateral disease, the prevalence of which is between 4,5% and 14%. The aim of our study is to evaluate the specific demographic and clinical characteristics and potential differences between bilateral and unilateral GO, and the association with disease activity and severity.</p...

ea0090p516 | Thyroid | ECE2023

Hyalinizing trabecular tumor of the thyroid gland. A rare entity with atypical cytological features A case report

Boutzios Georgios , Tsourouflis Gerasimos , Gakioloulou Charikleia , Destouni Maria , Chatzi Sofia , Giovannopoulos Ilias

Introduction: Hyalinizing trabecular tumors are extremely rare and uncommon thyroid tumors, which were first described by Carney et al. Until now, their preoperative diagnosis based on cytological characteristics is not possible, because of the lack of specific features and molecular markers.Case presentation: We present a 38-year-old Caucasian female, non-smoker, with a disease-free medical history, with a right-sided clearly delimited large hy...