Endocrine Abstracts

Introduction: Ectopic somatotroph adenomas are very rare and their mechanism is still debated. Our aim was to report 2 cases: One was located in the clivus and the other one in the supra sella area.Case 1A woman aged 45 years old, treated for post surgical hypothyroidism, was diagnosed as acromegaly by the family doctor. Growth hormone (GH)=44 ng/ml, IGF1=504 ng/ml (150–350). Prolactin (PRL)=37 ng/ml. The rest of pituitary fun...

Immature teratoma arising from the brain is very rare. The intra and supra sellar localization is very exceptional. Its clinical symptoms and radiological aspects on TDM are similar to those of craniopharyngiomas but on MRI the fat signal characterize teratomas, but only the histological exam gives the confirmation of this last lesion and makes differential diagnosis with mature tumor whose prognosis is better than the immature one. Our observation illustrates all these proble...

Nowadays neuro-radiological explorations are so frequent that radiologists discover more and more pituitary lesions. In this work we would like to study pituitary microlesions (PML: inferior or equal to 10 mm) in order to analyze age and sex repartition, clinical symptoms leading to the diagnosis, position in the pituitary area and the apparent etiologies.All our patients are examined and hormonal exploration is as complete as possible.<p class="abst...

Background: The craniopharyngioma is a non-endocrine tumor, developed along the infundibulo-pituitary axis, from the 3rd ventricle to sphenoid, histologically benign but locally invasive. It is a tumor with serious complications because of its location, its considerable potential for extension, its tendency to recur, and its adhesions to neighbouring structures. Our aim is to assess hormonal, neuro-ophthalmological and metabolic complications at the diagnosis of cra...

Introduction: Malignant feminizing adrenal tumors are very rare occurring generally in men. The lack of gynecomastia is even rarer in those tumor secreting estrogens alone, or with other adrenal hormones especially cortisol as in the following case.Case report: A male aged 44, consulted in May 2012 for abdominal pain. Radiological assessment discovered a large tumor measuring 120×95 mm located in the left adrenal with numerous metastases (pulmonary,...

Cardiothyreosis (CT) is defined as an association of hyperthyroidism (HT) with severe heart complications such as rhythmic troubles, heart and/or coronary insufficiency. Recently ventricle-auricular block and arterial pulmonary hypertension (APHT) was added to the definition. CT is the most frequent and one of the most dangerous complications of hyperthyroidism (HT) in emerging countries compared to developed countries where this abnormality is deemed to be very rare. Our aim ...

Introduction: Primary hyperparathyroidism (HPT) is usually observed in old people. It is very rare in children and young adults. Our aim is to analyze clinical, biological aspects, and outcome in six subjects under 30.Methods: The six subjects were chosen among 36 people hospitalized for primary HPT from 2009 to 2012. All had clinical examination, routine analyses, biological (blood and urinary calcium and phosphorus, and vitamin D) and hormonal (at leas...

Introduction: Dopamine agonists are commonly used for the treatment of Parkison’s disease and prolactinomas. Sometimes high doses are needed in mixed pituitary adenomas. This medical treatment usually induces gastrointestinal troubles and/or low blood pressure, and sometimes psychiatric disorders. Pleuropercarditis effusion (PPE) is rarely related to dopamine agonist side effects.Case report: Our aim is to report a man aged 29 years old whose PPE is...

Introduction: Baraitser–Winter syndrome (BWS) is a rare brain malformation leading to droopy eyelids and intellectual disabilities. This syndrome, first reported in 1988, is probably due to genetic abnormalities that are still not well defined, although eight gene abnormalities are already discovered and de novo missense changes in the cytoplasmic actin-encoding genes ACTB and ACTG1 have been recently discovered (Riviere Nature Genetic 2012). The syndrome combine...

Introduction: Pituitary hyperplasia (PH) is relatively a rare condition in children. As in adults, it can be secondary to a long-standing primary hypothyroidism and can sometimes be mistaken with a pituitary macro-adenoma as in the following observation:Case report: Herein, authors describe a girl aged 10 years old sent by her neurosurgeon for pre operative hormonal exploration of a pituitary macro adenoma measuring 13 mm in height. This one was discover...