Endocrine Abstracts

Introduction: Although pericardial effusion is a common finding in primary hypothyroidism, massive pericardial effusion or pericardial tamponade are rare. Herein, we describe a newly diagnosed case of primary hypothyroidism initially presenting with massive pericardial effusion.Case report: A 64 years old male patient attended to the emergency unit with worsening dyspnea over the past 1 month. ECG showed a low voltage QRS wave. Chest X-ray showed increas...

Introduction: Ectopic adrenocorticotropic hormone (ACTH) syndrome is characterized by hypercortisolism due to the hypersecretion of non-pituitary ACTH-secreting tumor leads to the Cushing’s syndrome. Herein, we present a case with Cushing’s syndrome, which is diagnosed ACTH-secreting renal malignant paraganglioma.Case: A 40-year-old woman presented with a 5 month history of newly diagnosed hypertension and diabetes, weakness, hyperpigmentation,...

Introduction: Polycystic ovary syndrome (PCOS) is a common endocrinopathy associated with increased cardiovascular risk in reproductive aged women. Circulating osteoprotegerin (OPG) and soluble receptor activator of nuclear factor κB ligand (sRANKL) are associated with subclinical atherosclerosis. Our aim is to evalutate serum OPG and sRANKL levels and their relations with cardiovascular and metabolic markers in paients with obese and non-obese PCOS.<p class="abstext"...

Introduction: Thyroid incidentaloma detected by FDG-PET/CT (flourodeoxyglucose positron emition tomography/computed tomography) is important because of high rate of malignancy. Elastosonograpghy has proven valuable in discriminating malign and benign thyroid lesions. In this study, we aimed to evaluate PET incidentalomas by ultrasonography and elastosonography and to compare cytopathological results with imaging findings.Methods: A total of 50 patients i...

Introduction: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders among women of reproductive age. A disintegrin and metalloproteinase with thrombospondin-like motifs (ADAMTS) are involved in inflammation and fertility. The aim of this investigation was to evaluate to serum levels of ADAMTS1, ADAMTS5, ADAMTS9, IL17, IL23, IL33 and to find out the relationship between these inflammatory cytokines and ADAMTSs in PCOS patients.Met...

Introduction: Vitamin D deficiency is a common health problem. Vitamin D supplements are used to improve vitamin D status. However, there are few data about what doses to give and how often to give. The aim of this study is to determine the effects of single high dose or daily low dose oral cholecalciferol (vitamin D3) on vitamin D levels and muscle strenght.Methods and design: 60 healthy postmenouposal women who had serum vitamin D levels wer...

Introduction: The relationship between hyperthyroidism and voice disorders has not been identified before. The aim of this study was to investigate the changes in the acoustic values in patients with subclinical thyrotoxicosis.Methods: In this study, acoustic voice analysis was evaluated in a total of 115 cases. Sixty of 115 individuals (18 men and 42 women) had subclinical thyrotoxicosis, aged between 18 and 65 years, and all had no history of laryngeal...

Introduction: Levothyroxine sodium (LT4) is widely used thyroid hormone to treat hypothyroidism. It is generally recommended to take it in the morning and hungry. Several studies about timing of thyroid hormone administration have shown different effects on TSH and FT4. The aim of this study is to determine the effects of timing of LT4 administration on TSH and the clinical outcomes.Method: The study group includes 65 pat...

Introduction: While mediastinal parathyroid carcinoma is a rare entity by itself, multiglandular coexistence of parathyroid carcinoma and adenoma represents an extremely rare condition. Herein, we report such a rare presentation of multiglandular parathyroid neoplasm with an ectopic carcinoma in the mediastinum and adenoma on the right side of neck in a patient with persistent primary hyperparathyroidism (PHP).Case report: A 38-year-old female patient wh...

Aim: Cardiac rhythm abnormalities have been documented in acromegalic patients. Our aim is to evaluate atrial electromechanical delay (EMD) with tissue doppler imaging (TDI) in patients with acromegaly.Material and methods: Fourty patients with acromegaly (13 patients with remission disease and 27 patients with active disease; 22 women and 18 men; mean aged 46.1±10.3 years), and 37 age- and sex-matched healthy controls were enrolled in the study. At...