Endocrine Abstracts

The Sheffield Children’s Diabetes Team [SCDT] look after approximately 240 patients with Type 1 Diabetes aged 0–17 years. We have approximately 35 newly diagnosed patients each year and the level of social deprivation amongst our clinic population is high. Historically the team has always performed well in terms of measured outcomes and in the 2014–2015 National Paediatric Diabetes Audit [NPDA] data we ranked amongst the top five units in the country with a mean...

Background: National Paediatric Diabetes Audit report 2012–2013 showed an increase in the number of patients with HbA1C >80 mmol/l at our paediatric diabetes unit.Aim: Two methods of intensive support for patients with high HbA1C were trialled- monthly clinics and weekly telephone contact.Method: From January to June 2014 we offered monthly ‘Target’ clinic appointments to a cohort of ten patients with high HbA1C....

Introduction: An update of health economics analysis of diabetes mellitus (DM) in Turkey was performed. The primary objective was to collect and calculate the healthcare resources utilized for the management of DM.Methods: Thirty-one out of 40 randomly chosen centers completed the study. Medical files were reviewed for the data recorded for at least two years prior to the study. Collected data included laboratory tests, treatments, inpatient/outpatient f...

Introduction: Gestational diabetes mellitus (GDM) is a risk factor for maternal-fetal complications and development of diabetes or intermediate hyperglycemia after pregnancy. The follow-up should be done by a multidisciplinary team. After delivery, all women diagnosed with GDM should undergo an oral glucose tolerance test (OGTT) for reclassificationAim: To evaluate the non-adherence factors to reclassification OGTT after GDM.Method...

Introduction: Gestational diabetes mellitus (GDM) is a risk factor for large for gestational age (LGA) newborns. The optimization of glycemic control and weight gain restriction during pregnancy according to BMI has contributed to decrease LGA but may increase the risk of small for gestational age (SGA).Aim: To evaluate the predictors of SGA in women with DGM.Methods: A cohort of 5271 Portuguese women from the National Registry of ...

Introduction: Nutritional therapy is essential in the treatment of gestational diabetes mellitus (GDM). International recommendations suggest a target of 5–9 kg weight gain in obese women during pregnancy. However, some studies advocate a reduced weight gain (<5 kg) due to better obstetric and neonatal outcomes, compared to an adequate or excessive weight gain.Aim: To compare obstetric and neonatal outcomes of obese women with GDM wit...

Introduction: In latent autoimmune diabetes of adults (LADA), the progression to insulin-dependent diabetes is usually faster than in type 2 diabetes (T2DM) but the factors influencing this progression are not completely known. The aim of the present study was to determine whether GADA could be used as predictors of insulin dependence and whether GADA titre could define the risk of progression to insulin therapy in LADA patients. We looked for other biochemical and clinical pa...

Introduction: In the last years, we have seen a high migration rate of people to Portugal. Not much is known about diet and lifestyle habits in some of these migrant women with gestational diabetes mellitus (GDM). On the other hand, communication can be a barrier and health care access may be more limited. For this reason, it is important to investigate whether there are differences in outcomes between these two populations, in order to question the need to change our clinical...

Introduction: LADA is a heterogeneous population of diabetes subjects wherein subgroups can be identified based on their autoimmune status: the titre of autoantibodies to GAD.The aim of the study was to correlate, in LADA subjects, GADA titre, with the presence of other organ and non organ specific autoantibodies.Methods: LADA subjects (n=191) and type 2 diabetes (T2DM) subjects (n=382) were selected from the Non Insu...

Objective: Brachial-ankle pulse wave velocity (baPWV) was used as a noninvasive marker of arterial stiffness. The aim of this study was to assess the association between arterial stiffness and cause specific mortality in patients with type 2 diabetes mellitus (T2DM).Methods: This multicenter prospective observational study analyzed 2,320 patients with T2DM. The patients were divided into two groups according to baPWV (cutoff baPWV of 1,750 cm/s). Causes ...