Searchable abstracts of presentations at key conferences in endocrinology

ea0067gp29 | Poster Presentations | EYES2019

Relapsed acromegaly after 3 years of remission following pituitary apoplexy

Dobre Ramona , Niculescu Dan Alexandru , Poiana Catalina

Background: Pituitary apoplexy is a rare clinical syndrome manifested by rapid enlargement of a pituitary mass. When apoplexy occurs in functioning adenomas, it may result in spontaneous remission with or without associated hypopituitarism. Cases of recurrence in such patients are reported in literature.Case description: We present a case of a 44 years old male, overweight and dyslipidemic that presented to our clinic in 2016 and was diagnosed with acrom...

ea0063p480 | Calcium and Bone 2 | ECE2019

Seasonal variation of osteoporotic hip fracture admitted in trauma centers in Bucharest

Dobre Ramona , Niculescu Dan Alexandru , Poiana Catalina

Hip fracture remains the most important clinical manifestation of osteoporosis, with many studies demonstrating a relationship between seasons and the incidence and mortality after hip fracture.Objective: We aimed to identify a seasonal variation (four seasons) in incidence of osteoporotic hip fracture admitted in trauma centers in Bucharest.Materials and methods: We observed the seasonal variation of 1176 patients, mean age 78.19+...

ea0070aep196 | Bone and Calcium | ECE2020

Epidemiology of osteoporotic hip fracture in the largest urban area of Romania

Dobre Ramona , Dan Alexandru Niculescu , Catalina Poiana

Background: Osteoporotic hip fracture remains a problem of public health concern. Different studies highlighted the existence of a particular epidemiology derived from local differences. We aimed to evaluate the epidemiology of osteoporotic hip fracture in the capital city of Romania plus city suburban area.Methods: We collected data from over 95 % of fractures from hospitals with an Orthopedic Surgery Department in the area of interest. Patients were se...

ea0081p247 | Late-Breaking | ECE2022

Long-term mortality and excess mortality after hip fracture in the main urban area of Romania

Dobre Ramona , Ruzandra Poiana Ioana , Alexandru Niculescu Dan , Cirstoiu Catalin , Popescu Gheorghe , Poiana Catalina

Background: Excess mortality after hip fracture remains a problem of public health concern. Until present, for Romania no data is available regarding long term mortality rate and excess mortality after hip fracture. We aimed to evaluate the mortality rate 3 years after hip fracture and also standardized mortality rates of osteoporotic hip fracture in the capital city of Romania and suburban area.Methods: we collected data from over 98 % of fractures admi...

ea0070aep241 | Bone and Calcium | ECE2020

Bone turnover markers and bone quality between patients with hyperthyroidism and primary hyperparathyroidism

Sorohan Madalina , Dusceac Roxana , Niculescu Dan , Baciu Ionela , Galoiu Simona , Dobre Ramona , Sorohan Bogdan , Poiana Catalina

Background: Hyperthyroidism is widely known to be an important cause of secondary osteoporosis through the accelerated rate of bone turnover, while primary hyperparathyroidism is typically associated with loss of cortical bone and less so of trabecular bone, as seen on dual-energy x-ray absorptiometry (DXA). The evaluation of bone quality in these categories is not fully understood and needs further research. The aim of this study was to compare the bone quantity and quality, ...

ea0056p181 | Bone ' Osteoporosis | ECE2018

PTH correlates with bone turnover serum markers in patients with end stage renal disease

Dusceac Roxana , Niculescu Dan Alexandru , Dragne Madalina Cristina , Dobre Ramona , David Cristiana , Tacu Cristian , Poiana Catalina

Background: End stage renal disease is usually associated with high serum parathyroid hormone (PTH) and increased bone turnover. The aim of our study was to correlate serum PTH with serum markers of bone turnover in patients with end stage renal disease (ESRD).Methods: We measured serum PTH, osteocalcin, procollagen type 1 n-terminal propeptide (P1NP) and beta-crosslaps in 64 (32 men) consecutive pacients, median (25, 75 percentile) age 61 (49.5, 65.5) y...

ea0056ep113 | Pituitary and Neuroendocrinology | ECE2018

Serum concentration of insulin-like growth factor I (IGF-I): reference values for adult Romanian population: Preliminary results

Alexandru Niculescu Dan , Dobre Ramona , Caragheorgheopol Andra , Popescu Nicoleta , Poiana Catalina

Background: Growth hormone, age, sex, genetics or nutrition status play an important role in insuline-like growth factor 1 (IGF-1) liver production and serum levels. Currently, there is no IGF-I reference range for Romanian population.Aim: To define sex- and age-adjusted reference values for serum IGF-I measured by an automated chemiluminescence immunoassay in adult Romanian population of healthy subjects.Methods: The study include...

ea0081p44 | Calcium and Bone | ECE2022

Bone mineral density, trabecular bone score and vertebral fractures in acromegalic patients

Sorohan Madalina , Dobre Ramona , Baciu Ionela , Galoiu Simona , Dusceac Roxana , Niculescu Dan , Caragheorgheopol Andra , Iordachescu Carmen , Poiana Catalina

Background: Acromegaly is characterized by increased prevalence of fragility vertebral fractures. Nonetheless, there are no clear recommendations for prevention of acromegalic osteopathy. Both bone mineral density (BMD) and trabecular bone score (TBS) lack clear evidence as prognostic factors for vertebral fractures (VF).Material and Methods: We performed an observational study on 31 acromegalic patients recruited prospectively. They were tested for alka...

ea0070ep327 | Pituitary and Neuroendocrinology | ECE2020

Conservative management of pituitary apoplexy – a case series

Trifanescu Raluca , Niculescu Dan Alexandru , Cristescu Alexandru , Alexandra Smarandoiu Georgiana , Dobre Ramona , Caragheorgheopol Andra , Hortopan Dan , Dumitrașcu Anda , Poiana Catalina

Introduction: Pituitary apoplexy is a rare complication in 2%-12% of pituitary adenomas, due to sudden hemorrhage or infarction. Patients with signs of meningeal irritation, important visual field defects, ocular paresis, decreased unilateral or bilateral visual acuity or altered consciousness are treated by neurosurgical intervention, while patients without these signs could be managed conservatively.Aim: To present a series of 4 cases with pituitary ap...