Endocrine Abstracts

Introduction: Multiple endocrine neoplasia type 1 (MEN1) is a rare, heritable syndrome characterized by a hyperparathyroidism, pituitary adenoma and pancreatic islet cells.Case: A 56-year-old male patient had a single parathyroid excised for primary hyperparathyroidism 10 years ago. He was further investigated due to hypoglycemia and a mass was found in the head of the pancreas on MRI. It was reported as neuroendocrine tumor and no recurrence was found i...

Introduction: Langerhans cell histiocytosis (LCH) is a neoplastic histiocytic disorder that characterized by proliferation of abnormal Langerhans cells. The most typical organs affected by LCH are the skin and bones, though it can also affect the pituitary gland, central nervous system, liver, spleen, lungs, and other organs.Case 1: 36 year old man presented with polyuria, polydipsia and right hip pain lasting about 4 months. The pain increased in the la...

Cushing’s syndrome as a result of ectopic adrenocorticotropic hormone (ACTH) secretion, is associated with various tumors. Lung squamous cell carcinoma (LUSC) causing ectopic ACTH syndrome is a very rare condition. A 70-year-old male patient with a history of LUSC was admitted to our clinic for evaluation of worsening delirium and hypokalemia. Two courses of pembrolizumab were administered to our patient who was diagnosed with LUSC a month ago. At presentation, neurologic...

Tuberculosis (TB) is a disease that affects all organs and progresses with a wide variety of clinical manifestations. Cases of extrapulmonary tuberculosis (EPTB) are particularly difficult to diagnose because of its atypical course.Case: A 32-year-old female patient was evaluated in our clinic with the complaint of localized swelling in both supraclavicular regions (ScR) for one and a half months. There were no fevers, cough, or weight loss symptoms pres...

Introduction: Ectopic neurohypophysis is a congenital abnormality related to faulty embryogenesis resulting in incomplete caudal extension of the infundibulum. It may present itself with symptoms of growth hormone deficiency or panhypopituitarism and patients require replacement treatment for panhypopituitarism.Case Presentation: Our female patient was shorter (138 cm) than her peers and did not menstruate at the age of 19 when she first...

Introduction: Myxedema coma is very rare and its mortality is quite high. It is even rarer to occur due to an immune checkpoint inhibitor.Case: A 69-year-old patient presented with complaints of dyspnea, fatigue, edema, and hypotension. He had diabetes mellitus, hypertension, and metastatic lung cancer diagnosis. Three weeks ago, he had taken the 10th cycle of atezolizumab for lung cancer, which he had been taking for 7 months. The patient’s body te...

Introduction: Primary thyroid lymphoma is a rare malignancy. In many series, it is reported that it is seen at a rate of 0.6-5% among thyroid cancers and approximately 2% among extranodal lymphomas. It is often seen as a painless mass in the neck. Almost all of them have underlying Hashimoto’s thyroiditis. In many instances, thyroid lymphoma was recognized after thyroid surgery for suspected carcinoma. The most common thyroid lymphomas are B-cell and Hodgkin lymphomas. Th...

Lymphocytic infundibuloneurohypophysitis (LINH) is rarely reported due to lymphocyte infiltration in the neurohypophysis. Causes of central diabetes insipidus include idiopathic diabetes insipidus (DI), primary or secondary tumors or infiltrative diseases (such as Langerhans cell histiocytosis, lymphocytic hypophysitis), neurosurgery and trauma.Case: A 59-year-old female patient presented with complaints of fatigue for 1 month, dry mouth and drinking a l...

Introduction: Rathke Cleft Cysts(RCCs) are benign cysts arising from the remnants of Rathke’s pouch. The most common symptoms are visual field disorders, headache, and pituitary dysfunction. Case 1: A 26-year-old male was admitted with headache that started 4 days ago. Cranial MRI revealed an appearance mimicking a hemorrhagic adenoma in pituitary. Pituitary hormones were found as normally. Pituitary MRI showed a 12x10x10 mm hemorrhagic RCCs located...

Introduction: Rathke Cleft Cysts(RCCs) are benign cysts arising from the remnants of Rathke’s pouch. The most common symptoms are visual field disorders, headache, and pituitary dysfunction. Case 1: A 26-year-old male was admitted with headache that started 4 days ago. Cranial MRI revealed an appearance mimicking a hemorrhagic adenoma in pituitary. Pituitary hormones were found as normally. Pituitary MRI showed a 12 x 10 x 10 mm hemorrhagic RCCs loc...