Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep1072 | Thyroid (non-cancer) | ECE2016

Iodine status and thyroid volume in pregnant women

Dolores Ollero M , Toni Marta , Martinez Juan Pablo , Pineda Jose Javier , Espada Mercedes , Anda Emma

Introduction: Adequate iodine intake is important in pregnant women.Objective: To determinate iodine status and thyroid volumen (TV) in healthy pregnant women from Navarra (Spain), and to evaluate possible influence of diet.Methods: A cross-sectional study of 144 women in the first trimester of pregnancy (single pregnancies) was carried during 2014. We measured thyroid-stimulating hormone (TSH), free thyroxine (fT4) and antithyroid...

ea0020p549 | Neuroendocrinology, Pituitary and Behaviour | ECE2009

High TSH levels in healthy pregnant women are related to a decrease in motor development of their children at 14 months of age

Alvarez Mar , Julvez Jordi , Guxens Monica , Rodriguez Agueda , Martorell Rosa , Espada Mercedes , Sunyer Jordi

Objectives: The fetus is dependent on maternal thyroid hormones during pregnancy and an adequate thyroid function during pregnancy is essential for the normal brain development. The effects of subclinical hypothyroidism during pregnancy are poorly known. The present study assesses the association between thyroid hormones and thyrotropin in healthy pregnant women from the general population, and the neurodevelopment of their children at the age of 14 months.<p class="abstex...

ea0056p1073 | Thyroid (non-cancer) | ECE2018

Serum thyroglobulin as a biomarker of iodine status in pregnant women

Dolores Ollero M. , Anda Emma , Toni Marta , Pablo Martinez Juan , Espada Mercedes , Javier Pineda J.

Serum thyroglobulin (Tg) is a biomarker used to assess iodine nutrition status, but data in pregnant women are scarce.Objectives: To determine serum Tg concentration in Spanish healthy pregnant women, and to evaluate its relation with yoduria (UIC), thyroid volume, iodine intake and thyroid function throughout pregnancy.Methods: Longitudinal study in pregnant women with no history of thyroid disease, recruited in 2 obstetric center...

ea0063p1167 | Thyroid 3 | ECE2019

Effect of maternal thyroid function on neonatal thyroid screening results

Ollero M Dolores , Esteban Juan Pablo Martinez de , Pineda J Javier , Anda Emma , Toni Marta , Espada Mercedes

Evidence on whether neonatal thyroid screening results are dependent on maternal thyroid function is limited.Objectives: To study the relationship between iodine status and maternal thyroid function in pregnancy, and neonatal screening results in a Northern Spanish population.Methods: Prospective, longitudinal study of 297 pregnant women recruited in 2 obstetric centers of Pamplona (Spain) at the first antenatal visit, and their ne...

ea0020p507 | Endocrine Disruptors | ECE2009

The association between organochlorine compounds, iodine intake and thyroid hormones during pregnancy

Alvarez-Pedrerol Mar , Guxens Monica , Rodriguez Agueda , Martorell Rosa , Espada Mercedes , Rebagliato Marisa , Ibarlucea Jesus , Sunyer Jordi

Objective: An adequate thyroid function during pregnancy is essential for the normal brain development of the foetus, and some organochlorine compounds (OCs) can interfere with the thyroid system. The objective of the present study was to evaluate the association between exposure to some OCs and thyroid function in pregnant women from two different areas in Spain, as well as to investigate the potential confounding effect of iodine intake.Methods: Thyroi...

ea0020p522 | Paediatric Endocrinology | ECE2009

Iodine levels and thyroid hormones in healthy pregnant women and birth weight of their offspring

Alvarez-Pedrerol Mar , Guxens Monica , Mendez Michelle , Canet Yolanda , Martorell Rosa , Espada Mercedes , Plana Estel , Rebagliato Marisa , Sunyer Jordi

Introduction: The fetus is the most vulnerable to severe iodine deficiency and hypothyroidism during pregnancy. Severe iodine deficiency and hypothyroidism during pregnancy have long been known to be associated with neurologic deficits and mental retardation The effects of mild iodine deficiency and subclinical hypothyroidism are poorly known. The present study assesses the association between thyroid hormones and urinary iodine concentration (UIC) in healthy pregnant women an...

ea0049ep1332 | Thyroid (non-cancer) | ECE2017

Iodine content of iodized salt in Spain

Arosa Vanessa , Goitia Maider Sanchez , Espada Mercedes , Irigoyen Luis , Maldonado Gonzalo , Arrizabalaga Juan Jose , Santiago Piedad , Orosia Maria , Menendez Edelmiro , Vila Lluis , Wengrowicz Silvia , Donnay Sergio

Introduction: Optimization of iodine intake aims to prevent the irreversible damage that iodine deficiency (ID) can cause in the central nervous system during its development, as well as thyroid disorders that can be induced by both ID and excessive micronutrient intake. The Spanish legal regulation stipulates that iodized salt (IS) must contain 60 mg of iodine per kg of salt (60 ppm), allowing a tolerance of ±15%. The aim of this study is to address the iodine content of...

ea0073aep736 | Thyroid | ECE2021

Nutritional status of iodine in the basque country

Alicia Martín Nieto , Isabel Benito Castaño , Urrutia Etxeberria Ines , Mercedes Espada Saenz-Torre , Arana Arri Eunate , Juan Del Olmo Sedano , Aguayo Calcena Anibal , Josep Oriol Casanovas Marsal , Gaztambide Saenz Sonia , Luis Castaño Gonzalez

BackgroundIodine is an essential nutrient necessary for the synthesis of thyroid hormones. Humans need a daily intake of 90–250 µg per day. The WHO criteria on the adequate iodine intake in the general population is: median iodine 100–199 µg/l, levels <100 µg/l in <50% of the population; <50 µg/l in <20% of the population and iodized salt consumption in >90% of households.Objectives...