Searchable abstracts of presentations at key conferences in endocrinology

ea0014s24.3 | Obesity | ECE2007

Adipokines and insulin sensitivity in humans

Fernández-Real José Manuel

Decreased insulin action has been proposed as the common factor that is in the background of the different components of the metabolic syndrome. Insulin resistance is also associated with a chronic activation of the innate immune system. The innate immune system constitutes the first line of body’s defence and it is constituted by different barriers (epithelia, adipose tissue), and different blood and tissue components as macrophages, and neutrophils. Once activated, the ...

ea0014p219 | (1) | ECE2007

Prevalence of metabolic syndrome in old men and its relation to ghrelin

Alfaro Sergio Rueda , Serra-Prat Mateu , Fernández Cristián Fernández , Palomera Elisabet , Casamitjana Roser , Domingo Manel Puig

Aim: To study the prevalence of metabolic syndrome (MS) and its relation with ghrelin in old men.Material and methods: Prospective-population based study (2002–2005) in which 153 independently living men older than 70 y were included. Comorbidities, physical exam, BMI, blood pressure were recorded and blood sample taken for biochemical and hormonal determinations. Metabolic syndrome was defined using IDF criteria.Results: MS w...

ea0073nsa4 | New Scientific Approaches 4: Multiplex analysis platform for endocrine disruption prediction using zebrafish | ECE2021

Multiplex analysis platform for endocrine disruption prediction using zebrafish

Jarque Sergio , Ibarra Jone , Rubio-Brotons Maria , Jessica García-Fernández , Terriente Javier

Small fish are excellent experimental models to screen endocrine-disrupting compounds, but current fish-based assays to detect endocrine disruption have not been standardized yet, meaning that there is not consensus on endpoints and biomarkers to be measured. Moreover, exposure conditions may vary depending on the species used as the experimental model or the endocrine pathway evaluated. Another drawback is the fact that most methods to detect endocrine disruption rely on the ...

ea0014p226 | (1) | ECE2007

Frequency of hypogonadism in males with type 2 diabetes and its relation with erectile dysfunction and obesity

García-Malpartida Katherinne , Casañ-Fernández Rosa , Yanini-García Jesús , Jover-Fernández Ana , Gómez-Balaguer Marcelino , Solá-Izquierdo Eva , Morillas-Ariño Carlos , Hernández-Mijares Antonio

Introduction: The aim of our study was to determine the frequency of hypogonadism (H) in males with type 2 diabetes (T2D) and its relation with erectile dysfunction (ED) and obesity.Methods: We studied 107 diabetic males who came successively to an Endocrine consultation. The presence of H was determined by total testosterone (T) with an immunofluerescence method and free testosterone (fT) calculated with Vermeulen’s equation, defining H if T<2 ...

ea0073aep408 | General Endocrinology | ECE2021

A new cause of endogenous hyperinsulinism?

Caballero Manuel J , José Ignacio Fernández Peña , Eyvee Arturo Cuellar Lloclla

We present the case of a patient who started having repeated episodes of symptomatic hypoglycemia at the age of 50.Medical historyFather had type 2 diabetes. Former smoker, moderate alcohol consumption. Chronic otitis media with cholesteatoma, surgically removed. Congenital cataract operated at the age of 3.Clinical courseAt around the age of 50, the patient started having sporadic epis...

ea0070aep376 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Phase angle (PA) and body composition changes in obese patients with associated comorbidities (by AACE criteria) through a very low calorie diet (VLCD) program

Maria Cornejo Pareja Isabel , Ma Vegas-Aguilar Isabel , Fernández-Medina Beatriz , Tinahones Francisco J , García-Almeida Jose Manuel

Introduction: Obesity is defined as a chronic disease by AACE/ACE. Includes presence/severity of complications. VLCD diets induce relevant weight loss by improving these complications. PA is a bioelectric measure of the cell mass and it is marker a global prognostic factor of cellular functionalism.Methods: Case-control retrospective study of severe obesity in a weight loss program comparing intensive intervention (41 cases, VLCD 800 kcal/d, 1g protein/k...

ea0070aep397 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Exposure to phenolic compounds (Bisphenol A and Methyl Paraben) in pregnancy and its relationship with gestational diabetes mellitus, insulin homeostasis and pancreatic beta cell function

Serrano Joaquin , Picó-Alfonso Antonio , Fernández Mariana F , Pedro Arrebola Juan , Alfayate-Guerra Rocio , Teresa López Maria , Moreno-Perez Oscar

Objectives: The effect of exposure to endocrine disruptors (exogenous chemical compounds that interfere with hormonal homeostasis), such as Bisphenol A (BPA) and Methyl Paraben (MPB), on gestational diabetes mellitus (GDM) has only been investigated in a small number of studies, with inconclusive results. Our objective was to investigate the association between concentrations of BPA and MPB in urine and the presence of DMG, insulin sensitivity and function of beta cells in a c...

ea0014p81 | (1) | ECE2007

Diabetic patient’s evaluation of continuous glucose monitoring sensors versus capillary glucose measurements

De Pinillos Gordillo Guilermo Martínez , Fernández-Argüelles Amaya , Garcí-Quirós Jm Juan Manuel

Objective: To evaluate the monitoritation systems acceptance: capillary glucose measurements and continuous glucose sensors (CGSM and GUARDIAN).Research design and methods: 15 diabetics patients were monitoritatied in two diferents periods of time. (Period 1: Guardian, 86 hours long. Period 2: CGSM 72 hours long). Later, they had to fill a satisfaction questionnaire concerning several aspects which were valued from 0–6.<table boarder="1" cellpad...

ea0014p511 | (1) | ECE2007

Pheochromocytoma in pediatric age

Fernández-Argüelles García Amaya , Morales Portillo Cristóbal , Campos Martín Cristina , Espino Rafael , López-Canti Luis

Introduction: Pheocrhomocytomas are rare tumors, principally benigns, and with high risk of morbimortality because of secretion of big amountos of catecholamines. They are an unfrequently cause of arterial hypertension in pediatric age but physicians must remember it because they can be diagnosed, treated and cured in a proper way.Objectives: To evalue the cases reports of pediatric pheochromocytoma found in our area, to analyze the differences in diagno...

ea0073pep9.8 | Presented ePosters 9: Endocrine-Related Cancer | ECE2021

Outcomes of a multicenter surveillance protocol in asymptomatic Succinate Dehydrogenase (SDH) B and C mutation carriers

Romero LLuch Ana R. , Disotuar Suset Dueñas , Tous Romero Marai C. , Fernández Peña J. Ignacio , Cuenca Cuenca J. Ignacio , Elena Navarro

IntroductionBased on the evidence available back then, in 2015 we developed a provincial multicenter protocol for screening and follow up of no-index patients with SDHB and SDHC mutations.Objectives1. To evaluate the performance of the protocol designed for the follow-up of asymptomatic SDHB and C carriers. 2. To describe the penetrance of manifestations associated with hereditary PGL-FEO syndromes type 3 and...