Searchable abstracts of presentations at key conferences in endocrinology

ea0049gp98 | Diabetes therapy & complications 1 | ECE2017

Gestacional diabetes mellitus: the new screening criteria and its outcomes

Gouveia Pedro , Sa Maritza , Resende Eduarda , Ferreira Margarida , Abreu Silvestre

Background: Gestational Diabetes Mellitus (GDM) is one of the most common illness of pregnancy. Despite its frequency, there’s no worldwide accepted screening criteria for GDM. In 2011, Carpenter and Coustan (CC) screening (50-g glucose challenge test (GCT) followed by 100-g glucose tolerance test (OGTT) if GCT screen was positive) was abandoned and began the implementation of the screening of the International Association of Diabetes and Pregnancy Study Group (IADPSG) 20...

ea0040p11 | (1) | ESEBEC2016

Acromegaly caused by hepatic metastasis of a pulmonary neuroendocrine tumor

Resende Eduarda , Gouveia Pedro , Sa Maritza , Ferreira Margarida , Abreu Silvestre

Introduction: Acromegaly is usually caused by a pituitary adenoma; ectopic or eutopic secretion of GHRH is a rare condition, responsible for <1% of the cases. Ectopic secretion of GH itself is even rarer.Case report: A 34-year-old woman was referred to the Endocrine Clinic with a multinodular goiter. However, on physical examination there were some physical signs of acromegaly: coarsening of facial features, protusion of the lower jaw and thick, oily...

ea0037ep1306 | Clinical Cases–Thyroid/Other | ECE2015

Takotsubo cardiomyopathy associated with levothyroxine over-replacement

Balsa Ana Margarida , Ferreira Raquel , Dantas Rosa , Guimaraes Joana

Background: Takotsubo cardiomyopathy (TC) is characterised by acute, transient left ventricular apical ballooning precipitated by emotional or physiologically stressful stimuli and has been previously associated with Graves’ disease based on few clinical reports. More recently, the association with exogenous thyrotoxicosis and radioiodine-induced thyroiditis has also been described. Iatrogenic hyperthyroidism on patients under levothyroxine replacement therapy for hypothy...

ea0032p235 | Clinical case reports – Pituitary/Adrenal | ECE2013

Acute pulmonary edema as the initial presentation of a pheochromocytoma: case report

Resende Eduarda , Sa Maritza , Ferreira Margarida , Abreu Silvestre

Introduction: The acute onset of pulmonary edema and severe congestive heart failure secondary to catecholamine overproduction from a pheochromocytoma is a rare entity, especially in the absence of other signs or symptoms suspicious of this tumour. Myocardial involvement can include angina pectoris, acute heart failure, dilated cardiomyopathy, myocardial infartion and arrhytmias. Here, we present the case of a young man with no significant medical history who presented with ac...

ea0090p620 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Mutation in MT-TV gene – a novel etiology of mitochondrial diabetes?

Ornelas Mariana , Resende Eduarda , Gouveia Pedro , Maritza Pontes Santos Sa Elena , Maria Morna Ferreira Margarida

Mitochondrial diseases are rare conditions with a wide phenotypic range. The inability of dysfunctional mitochondria to produce sufficient ATP results in multi-organic defects dependent on high aerobic such as pancreas. The most common endocrine disease related to mitochondrial diseases is diabetes mellitus and it is thought to be secondary to insulin deficiency. A 26-year-old pregnant patient with 26 weeks gestational age was referred to an Endocrinology appointment ...

ea0049ep1298 | Thyroid (non-cancer) | ECE2017

The role of 99mTc-sestamibi in amiodarone-induced thyrotoxicosis – Case report

Victor Margarida , Ferreira Ana Goncalves , Carmona Susana , Luiz Henrique Vara , Cordeiro Maria Carlos , Portugal Jorge , Santos Ana Isabel

Introduction: Amiodarone is an antiarrhythmic iodine-rich drug, known to induce thyroid dysfunction both due to its high iodine content and through amiodarone-induced thyrotoxicosis (AIT), being this latter process classified into three different types. Type 1 is associated with increased thyroid hormone synthesis; type 2 is a destructive process with thyroid hormone release and type 3 is thought to be a mixture of the former two. Since treatment options are different, there h...

ea0090ep595 | Endocrine-related Cancer | ECE2023

Immune checkpoint inhibitors induced endocrinopathies: a possible indicator of improved survival

Ornelas Mariana , Borges-Canha Marta , Gouveia Pedro , Maria Morna Ferreira Margarida , Resende Eduarda , Santos Sa Elena Maritza Pontes , Silvestre Abreu Francisco

Background: Immune checkpoint inhibitors (ICI) are an innovative oncologic therapy used in several types of solid and hematological neoplasms. This treatment enables the antitumoral immune system response and results in significant improvement of clinical outcomes and survival rate. However, endocrine related adverse effects (ERAE) have been related, with thyroid and pituitary dysfunction being the most common endocrine diseases described. An association between the surge of e...

ea0063p989 | Diabetes, Obesity and Metabolism 3 | ECE2019

Metformin and Vitamin B12 deficiency: evaluation of vitamin B12, homocysteine and methylmalonic acid levels in type 2 diabetics

Inacio Isabel , Azevedo Teresa , Alves Marcia , Dantas Rosa , Balsa Ana Margarida , Ferreira Sara , Rosinha Patricia , Gomes Fernanda , Fonseca Catarina , Garret Ana , Jesus Andreia , Guimaraes Joana

Introduction: The American Diabetes Association guideline states that the long-term use of metformin may be associated with biochemical vitamin B12 (B12) deficiency and periodic measurement should be considered, although isolated serum B12 measurement has low sensitivity and specificity. Homocysteine (Hcy) and methylmalonic acid (MMA) are more sensitive biomarkers, the latter being more specific.Objectives: To estimate B12 deficiency in type 2 diabetics ...