Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep403 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

The fatty acid profile in diabetic children

Castro-Correia Cintia , Sousa Sara , Norberto Sonia , Delerue-Matos Cristina , Domingues Valentina , Fontoura Manuel , Calhau Conceicao

Several studies have shown a link between pro-inflammatory activity and the presence or relative deficit of some fatty acids. A low amount of omega 3 fatty acids, appears to promote an inflammatory profile. The omega 6 fatty acids have also the same effect. It is well known that a chronic low-grade inflammation is associated to several diseases, namely, diabetes. The follow-up of children and young people with Type 1 diabetes involves the periodic evaluation of their lipidic p...

ea0049ep512 | Diabetes complications | ECE2017

Metabolic risk factors in adolescent girls with type 1 diabetes

Pinheiro Marta Isabel , Oliveira Juliana , Silva Rita Santos , Correia Cintia Castro , Fontoura Manuel

Background: Adolescent girls with type 1 diabetes (T1DM) have a higher incidence of metabolic risk factors like hypertension, dyslipidemia, non-alcoholic hepatic steatosis (NASH), abdominal adiposity and polycystic ovarian syndrome (PCOS) when compared with their non-diabetic peers. Moreover, metabolic risk factors seem to appear even in T1DM girls without overweight or obesity. We aimed to determine the prevalence of several metabolic risk factors in adolescent T1DM females, ...

ea0032p927 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Therapeutic response to recombinat somatropin in children with isolated deficiency of GH

Belo Sandra , Nogueira Claudia , Corujeira Susana , Costa Carla , Castro-Correia Cintia , Fontoura Manuel

Introduction: Generously supported by IPSEN)-->Treatment with recombinant ST is subject to strict criteria. Differences in the response to therapy based on the maximum level of ST in diagnostic tests (ST ≤5 vs ST >5 ng/ml), could predict whose patients would benefit more from therapy.Purpase: Assess differences in the response to therapy with rST in patients with IDGH.Methods: S...

ea0049gp227 | Thyroid Cancer | ECE2017

Fine needle aspiration biopsy in pediatric patients with thyroid nodules

Costa Maria Manuel , Silva Rita Santos , Castro-Correia Cintia , Sucesso Maria Bom , Coelho Tiago Henriques , Barroca Helena , Fontoura Manuel

Introduction: Although thyroid nodules (TN) are less common in children than in adults, the risk of malignancy is much higher in pediatric age and therefore representing greater concern in this age group.Objective: Evaluate a cohort of pediatric patients with TN and search differences between subjects with malignant and benign TN regarding sex, age, compressive symptoms, cervical ultrasound characteristics, family history of differentiated thyroid cancer...

ea0049ep1058 | Pituitary - Clinical | ECE2017

Clinical and laboratorial reassessment of patients with isolated growth hormone deficiency during the transition phase

Saavedra Ana , Oliveira Juliana , Martins Alexandra , Azevedo Ana , Santos-Silva Rita , Castro Cintia , Rodrigues Elisabete , Carvalho Davide , Fontoura Manuel

Introduction: During childhood and puberty, growth hormone(GH) is essential for linear growth. Consequently, children with isolated GH deficiency(GHD) must receive replacement therapy. GH has also important metabolic actions. GHD in adults is associated with altered body composition. However, long-term consequences of GH treatment in adults is not sufficiently known.Objective: To evaluate GH treatment during pediatric age in patients with isolated GHD.</...

ea0041gp142 | Paediatric Endocrinology &amp; Development | ECE2016

Association between urinary magnesium and glycaemic control in children and adolescents with type 1 diabetes mellitus

Cunha Filipe , Oliveira Juliana , Saavedra Ana , Alves Ines , Santos-Silva Rita , Costa Carla , Castro-Correia Cintia , Fontoura Manuel

Background: Hypomagnesemia is common in patients with diabetes; possibly due to higher renal magnesium excretion in those patients. Hypomagnesemia seems to correlate with poor glycaemic control. The relationship between urinary magnesium (UMg) and glycaemic control is not known. We aimed to study the association between UMg and glycaemic control in a type 1 diabetes (T1D) pediatric population.Methods: Study of a pediatric population with T1D attending th...

ea0026p403 | Thyroid (non cancer) | ECE2011

Thyroid nodules in children: review of 67 patients

Mesquita J , Lima S Paco , Matos M J , Neiva F , Pauperio S , Martins S , Costa C , Correia C Castro , Carvalho Davide , Fontoura Manuel

Introduction: Thyroid nodules in children and adolescents are less prevalent, but entail greater risk of malignancy than in adults. Most are asymptomatic because they are associated with normal thyroid function, but their prevalence is increasing due to the incidental diagnosis by neck ultrasound.Aims: To evaluate the characteristics of a pediatric population with thyroid nodules submitted to fine-needle aspiration (FNA) biopsy.Met...

ea0049ep887 | Growth hormone IGF axis - basic | ECE2017

Somatropin treatment Supported by NHS: characterization of submitted patients – 2006 to 2016

Bastos Margarida , Mirante Alice , Afonso Caldas , Vasconcelos Carlos , Bacelar Conceicao , Pereira Conceicao , Lopes Lurdes , Fonseca Marcelo , Serra-Caetano Joana , Patricio Miguel , Esteves Cesar Marques , Ferreira Florbela , Braganca Graciete , Raimundo Luisa , Matos Lurdes , Sampaio Lurdes , Fontoura Manuel , Borges Teresa

Introduction: In our country somatropin treatment is supported by the National Health Service. A National Committee (CNNHC) rules and analysis the submission papers of patients with: isolated/multiple somatotropin deficiency (STD), short stature in: renal chronic disease (DRC), small for gestational age (SGA), Turner syndrome (TS) and Prader Willi syndrome (PWS). In adults only isolated somatropin deficiency diagnosed in childhood.Aims: To analyze the ch...