Searchable abstracts of presentations at key conferences in endocrinology

ea0056p362 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Is it useful the O’Sullivan test ≥200 to diagnose gestational diabetes mellitus (GDM)?

Molina-Vega Maria , Picon-Cesar Maria Jose , Hernandez-Garcia Carmen , Damas-Fuentes Miguel , Diaz-Perdigones Cristina , Tinahones-Madueno Francisco

Introduction: A two-step approach is usually used to diagnose GDM. At 24–28 weeks of pregnancy, a 50 g 1-hour glucose or O’Sullivan test is performed. If it is positive (≥140 mg/dl), it is followed by a 100 g-3 hours-Oral Glucose Tolerance Test (OGTT) which is considered positive if at least two or more values are ≥ of reference values (105-190-165-145 mg/dl). Despite it is not include in any clinical practice guideline, sometimes the 100 g OGTT is obviat...

ea0063p42 | Adrenal and Neuroendocrine Tumours 1 | ECE2019

Endocrine hypertension?

Maraver-Selfa Silvia , Damas-Fuentes Miguel , Cornejo-Pareja Isabel Maria , Molina-Vega Maria , Munoz-Garach Araceli , Hernandez-Garcia Carmen , Mancha-Doblas Isabel , Tinahones Francisco

An 18-years-old woman without medical history was referred for study of hypertension and an adrenal incidentaloma. The family history was significant for essential well-controlled hypertension in her father; diagnosed at 39 years-old. The patient complained of headache, asthenia, edema in lower limbs, high blood pressure values (200/150 mmHg) for one year (well controlled with losartan 100 mg/12 h, amlodipine 10 mg/24 h and doxazosin 4 mg/24 h) and marked facial acne previous ...

ea0063p622 | Diabetes, Obesity and Metabolism 2 | ECE2019

Assessment of materno-fetal complications in pregnant women with type 1 diabetes exposed to insulin degludec

Martinez Montoro Jose Ignacio , Hernandez Garcia Carmen , Jose Picon Cesar Maria , Molina Vega Maria , Maria Diaz Perdigones Cristina , Damas Fuentes Miguel , Jose Tinahones Madueno Francisco

Introduction: Pregnancy in women with type 1 diabetes mellitus (T1DM) is associated with an increased risk of adverse outcomes, so pregnancy planning in order to achieve an optimal glycemic control is essential. This control has been made possible, in part, by the widespread use of insulin analogues, especially the long-acting ones, glargine and detemir. Insulin degludec, an ultra-long-acting insulin is not currently approved for pregnant women due to the lack of randomized co...

ea0063p717 | Pituitary and Neuroendocrinology 2 | ECE2019

Glycogenosis and hypofisis pathology, importance of a multidisciplinary management

Cornejo-Pareja Isabel , Maraver-Selfa Silvia , Munoz-Garach Araceli , Gonzalo-Marin Montserrat , Hernandez-Garcia Carmen , Damas-Fuentes Miguel , Mancha-Doblas Isabel , Tinahones Francisco J

Introduction: Glycogenosis is a group of hereditary diseases affecting the glycogen metabolism, due to mutations in enzymes involved in the transformation and synthesis of glucose (liver and muscle glycogenosis). Brain germ tumors are very infrequent. They are located mainly in pineal and sellar region. Central diabetes insipidus is the most frequent manifestation. Their prognosis and response to combined chemo/radiotherapy treatment are favorable.Case r...

ea0049ep614 | Diabetes therapy | ECE2017

New long-acting insulins in type 1 diabetes: implications for real clinical practice

Damas-Fuentes Miguel , Diaz-Perdigones Cristina , Munoz-Garach Araceli , Molina-Vega Maria , Hernandez-Garcia Carmen , Cornejo-Pareja Isabel , Mancha-Doblas Isabel , Tinahones-Madueno Francisco J

The emergence of a new generation of long-acting insulin analogues (insulin degludec -ID- and insulin glargine 300 U/ml -IG300-) has increased treatment options in type 1 diabetes (T1D), demonstrating in clinical trials better metabolic control with lower hypoglycemia rates.Objectives: To assess characteristics of T1D patients who were given ID and IG300 in clinical practice and to evaluate their effect on metabolic control, weight, insulin dose and hypo...

ea0049ep1462 | Thyroid (non-cancer) | ECE2017

Prevalence of thyroid cancer in malaga and province

Hernandez-Garcia Carmen , Munoz-Garach Araceli , Doulatram Viyu , Perez-Villa Lidia , Mellado-Soria J , Robles-Cabeza L , Gonzalez-Hermoso C , Tinahones-Madueno Francisco

Introduction: Thyroid cancer is the most common endocrine neoplasia, being its papirally version the most frequent. (90% of all differentiated thyroid neoplasms). It is usually multifocal and metastasizes normally to regional lymph nodes.Objectives: To describe the prevalence of thyroid cancer and its histopathological variants in the different regions of the province of Malaga.Material and methods: We performed a retrospective des...

ea0056p16 | Adrenal cortex (to include Cushing's) | ECE2018

Rare incidence of primary adrenocortical carcinosarcoma: a case report

Maria Diaz Perdigones Cristina , Maria Cornejo Pareja Isabel , Damas Fuentes Miguel , Molina Vega Maria , Hernandez Garcia Carmen , Munoz Garach Araceli , Jose Tinahones Madueno Francisco

Introduction: Adrenal tumors are common tumors with a prevalence of around 3% in a population over the age of 50 years. In contrast, adrenocortical carcinoma (ACC) is a rare malignancy (incidence 1–2 per 1 million population) with a heterogeneous presentation and a variable but generally bad prognosis. Patients present with evidence of adrenal steroid hormone excess in approximately 60% of cases.Case report: A 49-year-old woman with symptoms of faci...

ea0056p507 | Diabetes therapy | ECE2018

Efficacy in metabolic control and weight loss of combined treatment with GLP-1 receptor analogues and SGLT-2 inhibitors

Damas-Fuentes Miguel , Munoz-Garach Araceli , Maraver-Selfa Silvia , Molina-Vega Maria , Hernandez-Garcia Carmen , Diaz-Perdigones Cristina , Tinahones-Madueno Francisco

Introduction: The emergence of a new generation of antidiabetic drugs (GLP-1RA and SGLT-2i) with complementary mechanisms of action offer new alternatives in the treatment of patients with T2D and poor metabolic control.Objectives: To evaluate the efficacy of the aGLP-1 and iSGLT2 combination on metabolic control, weight, blood pressure and insulin dose in patients with DM2.Methods: Observational, retrospective study. We studied T2...

ea0063p10 | Adrenal and Neuroendocrine Tumours 1 | ECE2019

Study of body composition and phase angle in relation to nutritional parameters in patients with neuroendocrine tumors

Hernandez-Garcia Carmen , Cornejo-Pareja Isabel Maria , Damas-Fuentes Miguel , Martinez-Montoro Jose Ignacio , Diaz-Perdigones Cristina Maria , Bandera-Merchan Borja , Garcia-Almeida Jose Manuel , Tinahones-Madueno Francisco Jose

Introduction: Neuroendocrine tumors are an heterogeneous group of neoplasms with increasing incidence and high survival. The therapies, could be have a negative impact on nutrition and pronogsis of these patients.Objetives: To analyze analytical and anthropometric parameters in relation to disease stage and survival.Material and methods: An observational, retrospective and cross-sectional study that includes patients with neuroendo...

ea0049gp71 | Diabetes & complications 1 | ECE2017

Carbohydrates metabolism and H. pylori: case-control study

Cornejo-Pareja Isabel Ma , Roca-Rodriguez M Mar , Coin-Araguez Leticia , Munoz-Garach Araceli , Molina-Vega Maria , Diaz-Perdigones Cristina , Hernandez-Garcia Carmen , Alcaide-Torres Juan , Clu-Fernandez Carlos , Vinuela-Gonzalez Laura , Mora-Navas Laura , Mancha-Doblas Isabel , Tinahones-Madueno Francisco J

Introduction: H. pylori infection has been related with extragastric diseases such as type 2 diabetes.Aim: to evaluate changes in carbohydrate metabolism induced by 75g oral glucose tolerance test (OGTT), before and after antibiotic eradication treatment in patients colonized by H. pylori compared to healthy controls.Materials and methods: A prospective case-control study. Biochemical parameters, carbohydrate profile, ghrelin and G...