Endocrine Abstracts

Introduction: The update of 2015 American Thyroid Association (ATA) guidelines recommend that radioactive iodine (RAI) ablation therapy should be used in line with patients’ risk stratification. However, there is no consensus on benefits of post-operative RAI ablation in patients with low risk differentiated thyroid cancer (DTC). The aim of this study is to compare the outcomes of patients with low risk DCT submitted to RAI ablation with those who were not.<p class="a...

Background: To minimize potential harm from overtreatment of low-risk thyroid cancers, the 2015 American Thyroid Association (ATA) Guidelines recommend that radioactive iodine (RAI) ablation should not be routinely used in low-risk differentiated thyroid carcinoma (DTC). The present study aims to evaluate trends in RAI therapy in a tertiary center after the update of these Guidelines.Methods: Data from patients followed in a tertiary center with low-risk...

Introduction: Hypocalcaemia is a potential post-thyroidectomy complication. Patients with previous Roux-en-Y Gastric Bypass (RYGBP) are at increased risk of symptomatic hypocalcaemia refractory to treatment. This complication is rare and there is not consensus on how to act.Clinic case: Female with 34 years old, with a history of Obesity (BMI 45.7 kg/m2), submitted to RYGBP in 2013, with a total loss of 47 kg (current BMI 27.3 kg/m2...

Introduction: The hyperthyroidism is a risk factor for tachyarrhythmia and dilated cardiomyopathy. Amiodarone is an effective antiarrhythmic medication, however if coexisting thyroid pathology complicates the treatment of thyroid dysfunction. It presents a case of Graves’ disease (GD) of long evolution, which illustrates the complexity of these associations. Clinical case: man, 44 years old, smoker, history of acute myocardial infarction and GD diagnosed at age 28. Has ma...

Introduction: Clinical inertia applied to type2 Diabetes Mellitus (T2DM) treatment, is defined as a lack of treatment’s intensification of patients who are not in HbA1c target. Clinical inertia leads to a postponement of new therapeutic introduction, with all complications associated with a poor metabolic control. In Portugal there are only studies that show good or poor metabolic control but do not mention clinician’s attitude towards these values. Recently publishe...

Introduction: The SGLT-2 inhibitors (InibSGLT2) are the newest class of non-insulin antidiabetic drugs (ANI) for type 2 diabetes mellitus (T2DM) treatment. Currently is only available in Portugal, dapagliflozin. This pharmacological class have shown benefits in metabolic control (reduction of 0.5–0.8% HbA1c) and in weight loss (1–3 kg).Objective: Evaluate the impact of InibSGLT2 in patients with T2DM followed in a Diabetes department.<p cla...

Introduction: American Thyroid Association recommends that benign thyroid nodules should be revaluated 6–18 months after initial FNA and in case of stability the follow-up should be 3–5 years. However there isn’t any consensus about the periodicity of the follow-up.Aim: To evaluate the nodules in terms of function, size and malignancy in a 10-year follow-up.Methods: Retrospective study of 347 patients (543 benign thy...

Introduction: Postmortem studies have shown that a fifth parathyroid gland may be present in about 5% of patients with hyperparathyroidism. 1% of parathyroid glands are located in thyroid tissue. There’s a prevalence of 7–10% of thyroid ectopic tissue.Case report: A 53-year-old male, submitted to bilateral nephrectomy due to a Grawitz tumour at the age of 25. Under haemodialysis since then (with a rejected renal transplant in the past), he was ...

Introduction: Interaction between diabetes mellitus (DM) and an infection usually results in hyperglycaemia. However, there is data describing hypoglycaemia events related with the association between certain antibiotics and oral anti-diabetic drugs or insulin.Case report: Male, 73 years old, with history of hypertension, obesity and dyslipidaemia. DM type 2 was diagnosed 13 years ago with any macro or microvascular complications so far. Currently he&#14...

Introduction: Primary hyperaldosteronism (PHA) and pheochromocytoma are endocrine causes of secondary arterial hypertension. The association of hyperaldosteronism and pheochromocytoma is rare and the involved mechanisms are poorly understood. Either there is coexistence of the two diseases (pheochromocytoma with PHA) or the pheochromocytoma stimulates the production of aldosterone.Case Report: Male, 54 years old, referred to our department for type 2 dia...