Searchable abstracts of presentations at key conferences in endocrinology

ea0032p956 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Hyponatremia as a first sign of panhypopituitarism: empty sella

Dokupilova Adriana , Kollerova Jana , Payer Juraj

Introduction: Hyponatremia is the most common disorder of electrolytes encountered in clinical practice, occurring in up to 15–30% of both acutely and chronically hospitalized patients. Although most cases are mild and relatively asymptomatic, it is important clinically because: i) acute severe hyponatremia can cause substantial morbidity and mortality, ii) mortality is higher in patients with hyponatremia who have a wide range of underlying diseases and iii) overly rapid...

ea0041ep1080 | Thyroid (non-cancer) | ECE2016

Thyroid screening in pregnancy –preliminary data from our outpatient clinic

Palenikova Patricia , Kollerova Jana , Bednarova Adriana , Kuzma Martin , Payer Juraj

Introduction: The adverse impact of overt hypothyroidism that complicates pregnancy outcomes is well-established. In order to eliminate these complications has long been discussion about the need for early detection of the disease of the thyroid gland in the population of women planning pregnancy, respectively in early pregnancy. In Slovakia, this effort resulted in the approval of screening for thyroid diseases in pregnancy and has been enshrined in a legislative in 2009. Obl...

ea0032p249 | Clinical case reports – Pituitary/Adrenal | ECE2013

Extraadrenal paraganglioma: case report

Payer Juraj , Teliarova Zuzana , Jackuliak Peter , Kollerova Jana , Breza Jan

The presence of pheochromocytoma/paraganglioma can be characterized by typical clinical signs, due to hemodynamic and metabolic activity of circulating catecholamines or less a consequence of other amines or neuropeptides produced simultaneously. But the clinical picture can be also very different and can play a clinical picture of other diseases.The authors present a case report from a patient with retroperitoneal paraganglioma. The patient was admitted...

ea0016p436 | Neuroendocrinology | ECE2008

Prolactin levels in patients with cirrhosis increase with severity of liver disease

Payer Juraj , Koller Tomas , Baqi Lahim , Kollerova Jana

Background: Pituitary prolactin secretion is physiologically supressed by dopaminergic tonus from hypothalamus, which itself is under regulation by various hypothalamic releasing factors. We Disturbed dopaminergic tonus in patients with liver cirrhosis is suspected.The aim of our study was to measure prolactin levels in patients with cirrhosis and to investigate the relatioship between the severity of liver disease and other clinical and laboratory param...

ea0041ep721 | Male Reproduction | ECE2016

Is testosterone deficiency a real problem of male IBD patients?

Kollerova Jana , Hlavaty Tibor , Krajcovicova Anna , Leskova Zuzana , Koller Tomas , Payer Juraj

There have been many discussions about testosterone role in inflammation and autoimmunity. Inflammatory bowel disease (IBD) is a chronic autoimmune disease in younger age groups. The aim ouf our study was to evaluate testosterone concentration and it’s influence on disease acitivity and the quality of life.In our cross-sectional study we measured total testosterone levels in males with IBD (Crohn’s Disease, Ulcerative colitis). Age, BMI, main c...

ea0035p22 | Adrenal cortex | ECE2014

Hyponatremia as a predictor of in-hospital mortality

Sturdik Igor , Adamcova Monika , Kollerova Jana , Koller Tomas , Zelinkova Zuzana , Jackuliak Peter , Payer Juraj

Background: Hyponatremia is the most common electrolyte abnormality, it increases morbidity and mortality, but it is not clear if this condition influences mortality independently of other contributing factors. The aim of our study was to assess the relative contribution of hyponatremia to in-hospital mortality and to determine predictive factors associated with hyponatremia-related mortality.Materials and methods: A database search was conducted for all...

ea0020p246 | Bone/Calcium | ECE2009

The relationship between serum TSH, free T4 and bone mineral density in pre- and postmenopausal women

Baqi Lahim , Langer Pavel , Killinger Zdenko , Homerova Zuzana , Kollerova Jana , Banarova Adriana , Payer Juraj

Background: Thyroid-stimulating hormone (TSH) might influence bone mineral density (BMD) through its regulation of the thyroid hormones thyroxine (T4) and triiodthyronine (T3). Direct effect of TSH on bone turnover, mediated through its receptors on both osteoblast and osteoclast precursors, has been suggested. We wanted to explore the relationship between serum TSH, fT4 and BMD in women with different TSH levels after a long-term observation of thyroid function and bone statu...

ea0056p920 | Female Reproduction | ECE2018

Does Crohn’s disease have an effect on female fertility?

Kollerova Jana , Koller Tomas , Kadleckova Barbora , Toth Jozef , Krajcovicova Anna , Hlavaty Tibor , Payer Juraj

Introduction: Impaired fertility in women with Crohn’s disease compared to healthy women seems to be a consequence of Crohn’s disease, according to older studies. However, data are not consistent, and it is not clear why could the reduced fertility occur. Influence on ovarian reserve might be one of the answers.Patients: The study group consisted of women with Crohn’s disease. The control group consisted of age and BMI matched healthy wome...

ea0049ep1046 | Pituitary - Clinical | ECE2017

Heterogeneity of the patient pathway for adult growth hormone deficiency: Perspectives from a CEE Endocrinologists expert panel

Shimon Ilan , Badiu Corin , Bossowski Artur , Doknic Mirjana , Dzivite-Krisane Iveta , Hana Vaclav , Kollerova Jana , Natchev Natchev Emil , Pfeifer Marija , SzŨcs Nikolette , Hey-Hadavi Juliana , Gomez Roy

Introduction: Effective identification, diagnosis and management of growth hormone (GH) deficiency in adults are crucial for treating endocrinologists to provide the best in patient care. As such, it is important that we share our experiences to understand challenges and obstacles to enhance the patient journey. The objective of this project was to start identifying these challenges and obstacles.Methods and findings: In November 2016, an expert panel of...