Endocrine Abstracts

Introduction: Diabetes mellitus (DM) treatment has recently undergone major developments which have dramatically changed the management of the disease. During the twentieth century major changes in the treatment of DM have transformed the disease from an uncurable disease to a chronic one. However, some of the major drugs used for its treatment have remained stable, while others have now almost gone into disuse.Aim: The aim was to show the recent therape...

Graft vs host disease is a disorder in which the graft, i.e. bone marrow, attacks the host after bone marrow transplantation. It has various manifestations, one being skin and muscle involvement with cutaneous sclerosis and diffuse muscle pain. The aim was to describe the case of a patient with graft vs host disease complicated by insulin resistance and metabolic syndrome, after bone marrow transplantation for the treatment of acute lymphoblastic leukemia.<p class="abstext...

Tall cell papillary thyroid carcinoma is known to be associated with an adverse outcome, namely with the early development of locally recurrent or metastatic disease. Therefore the administration of therapeutic radioactive iodine is considered absolutely necessary in the management of such patients. A meningioma may occur in a patient with another neoplastic disease, having also been described in patients with thyroid carcinoma.The aim was to describe th...

Papillary thyroid carcinoma is a disease associated with a very good prognosis. However, there are some subtypes of papillary thyroid cancer which are associated with aggressive biological behavior and worse outcome. The appearance of brain metastatic disease in the course of papillary thyroid carcinoma is rare and carries an unfavorable prognosis.The aim was to describe the case of a patient with tall cell papillary thyroid carcinoma who presented with ...

Central diabetes insipidus is characterized by increased water excretion which is corrected by the administration of antidiuretic hormone. Hypercalciuria is known to be associated with osteoporosis. The aim was to describe the case of a patient with central diabetes insipidus, hypercalciuria, vitamin D deficiency and severe osteoporosis.The case of a patient, female aged 64 years, presenting with central diabetes insipidus, hypercalciuria, vitamin D defi...

Introduction: Infection from the severe respiratory distress syndrome coronavirus 2 (SARS-CoV-2) virus may present as mild disease or as severe disease with high mortality. Although the majority of patients infected by the virus have a good prognosis, chronic diseases, such as diabetes mellitus (DM), especially in older adults may be a risk factor for a worse outcome. DM is a frequent comorbidity in patients with COVID-19. Aim: The aim of the present wor...

Osteoporosis may be a disease of unknown etiology, or a degenerative disorder in the context of aging. Nowadays, the availability of multiple forms of effective drug treatment for osteoporosis have raised the hypothesis that osteoporosis may be not only a treatable but moreover a curable disease.The aim was to describe the case of a patient with osteoporosis who after treatment with alendronate for 6 years had osteopenia and remains in the state of osteo...

Primary hyperparathyroidism is known to coexist with thyroid cancer and breast cancer. However, primary hyperparathyroidism coexisting with Graves’ disease is extremely rare. The aim was to describe the case of a patient with Graves’ disease causing severe hyperthyroidism who in the course of the disease developed vitamin D deficiency and primary hyperparathyroidism. A patient, female, aged 49 years, presented with severe hyperthyroidism causing tachycardia, palpitat...

Stress appears to activate the immunoneuroendocrine network and seems to be related to the development of autoimmune diseases. Graves’ disease is a multisystem disorder characterized by hyperthyroidism, eye disease and pretibial myxedema. Stress appears also to be related to the development of Graves’ disease.The aim was to describe cases of Graves’ disease which developed immediately after a stressful life event.Pat...

Adrenocortical tumorigenesis has been observed in mice. It is speculated to be gonadotropin dependent. In particular LH receptors appear to be found within such adrenal tumors in high density and elevated LH levels may be related to adrenal tumorigenesis. The aim was to describe the case of a patient who after ovariectomy developed a large malignant adrenal tumor. A patient, female, aged 42 presented with uterine leiomyomas. She was treated by surgical excision of the uterus a...