Searchable abstracts of presentations at key conferences in endocrinology

ea0090ep103 | Adrenal and Cardiovascular Endocrinology | ECE2023

Steroid hormone withdrawal and autoimmunity induction

Athanassiou Lambros , Athanassiou Panagiotis , Kalavri Eleni , Tsakiridis Pavlos , Fortis Athanasios , Mascha Olga , Ifigenia Kostoglou Athanasiou

Introduction: Pregnancy is characterized by increased secretion of estrogens and cortisol. Estrogen is used to prepare the maternal environment for the fetus. Cortisol induces a state of immunosuppression to avoid loss of the fetus, which, by definition, is at least partly a foreign organism. Parturition is characterized by estrogen and cortisol withdrawal. It leads to a rebound in immunity and may be accompanied by the development of autoimmune disease. Autoimmune thyroid dis...

ea0090ep1071 | Thyroid | ECE2023

Transverse Myelitis and Covid-19 Disease in A Patient with Hashimoto’s Thyroiditis

Athanassiou Lambros , Athanassiou Panagiotis , Tsakiridis Pavlos , Nikolakopoulou Sofia , Mathiou Dimitra , Nikolidaki Maria , Athanasiou Ifigenia Kostoglou

Introduction: The SARS-CoV-2 virus has caused the recent pandemic. Most affected patients have gone through a rather mild disease. However, some of the patients have gone through a severe illness requiring admission to an acute care unit. Some survived while others succumbed to the disease. In some patients the SARS-CoV-2 infection was characterized by neurological manifestations. One of these is transverse myelitis thought to be caused either by the virus itself as the SARS-C...

ea0090p794 | Thyroid | ECE2023

Leukopenia A Benign Comorbitidy and Early Sign of Autoimmunity in Hashimoto’s Thyroiditis

Athanassiou Lambros , Athanassiou Panagiotis , Tsakiridis Pavlos , Nikolakopoulou Sofia , Nikolidaki Maria , Mathiou Dimitra , Fortis Athanasios , Athanasiou Ifigenia Kostoglou

Introduction: Leukopenia is a manifestation of autoimmune diseases such as systemic lupus erythematosus (SLE). Leukopenia may be an early sign of autoimmunity and may be a comorbidity in patients with autoimmune Hashimoto’s thyroiditis. Aim: The aim was to present a cohort of 12 patients with autoimmune Hashimoto’s thyroiditis who presented with leukopenia.Methods: A cohort of 12 patients, aged 19-72 y, female, with autoi...

ea0056p106 | Clinical case reports - Pituitary/Adrenal | ECE2018

Cushing’s syndrome in a patient with systemic lupus erythematosus

Kostoglou-Athanassiou Ifigenia , Spiliotis George , Athanassiou Lambros , Myriokefalitakis Ioannis

Introduction: Systemic lupus erythematosus is a systemic autoimmune disease, which often necessitates the administration of corticosteroids for its treatment. Cushing’s syndrome is a disorder characterized by the endogenous hypersecretion of cortisol.Aim: The aim was to describe the case of a patient who had systemic lupus erythematosus, was on therapy with corticosteroids and developed Cushing’s syndrome.Case description...

ea0081ep170 | Calcium and Bone | ECE2022

Vitamin D levels in relationship to thrombotic markers in severe Sars-CoV-2 infection

Kostoglou-Athanassiou Ifigenia , Athanassiou Lambros , Nikolakopoulou Sofia , Konstantinou Alexandra , Mascha Olga , Samaras Charilaos , Athanassiou Panagiotis

Introduction Severe infection from the SARS-CoV-2 virus is associated with various manifestations, including hematological manifestations. Thrombotic events or a tendency to develop thrombotic events also characterize severe COVID-19 disease and may be related to fatalities. Vitamin D is known to have immunomodulating properties and to enhance the body defense system against invading pathogens and to have immunostimulatory properties as far as the innate immune response is con...

ea0081ep238 | Calcium and Bone | ECE2022

Primary hyperparathyroidism and rheumatoid arthritis

Athanassiou Lambros , Kostoglou-Athanassiou Ifigenia , Mavroudi Maria , Tsakiridis Pavlos , Koukosias Nikolaos , Athanassiou Panagiotis

Rheumatoid arthritis is a systemic autoimmune inflammatory disease characterized by severe pain, if left untreated. Primary hyperparathyroidism is a systemic disorder characterized by disordered calcium metabolism leading to increased serum calcium and PTH levels. Primary hyperparathyroidism may be due to the presence of a parathyroid adenoma or parathyroid hyperplasia. The aim was to present a cohort of patients with rheumatoid arthritis who presented with primary hyperparath...

ea0063p545 | Diabetes, Obesity and Metabolism 2 | ECE2019

Lipid profile and cardiovascular risk in ankylosing spondylitis

Athanassiou Panagiotis , Tzanavari Aikaterini , Athanassiou Lambros , Dardavesis Theodoros , Ifigenia Kostoglou-Athanassiou

Introduction: Ankylosing spondylitis (AS) is a chronic systemic inflammatory disorder which affects the sacroiliac joints, the axial skeleton, peripheral joints as well as other organs. It develops in young adults causing significant mobility and functional disorders, with associated severe dysfunction or disability. Ankylosing spondylitis has serious adverse effects on the ability to work and quality of life. Biologic agents are used for the treatment of AS, this effect havin...

ea0063p1196 | Thyroid 3 | ECE2019

Stressful life events induce graves’ disease: further evidence for the role of stress as an inducing factor in graves’ disease

Kostoglou-Athanassiou Ifigenia , Athanassiou Lambros , Xanthakou Eleni , Spyropoulos Panagiotis , Kalogirou Thomais , Potamousi Paraskevi , Athanassiou Panagiotis

Introduction: Stress is a known risk factor for the development of Graves’ disease. We have previously described the role of bereavement as an inducing factor for Graves’ disease. Bereavement as an inducing factor for Graves’ disease was shown to affect primarily female patients after the loss of a loved one. However, it appears that other stressful life events may also cause Graves’ disease.Aim: The aim of the study was to describe t...

ea0063ep38 | Diabetes, Obesity and Metabolism | ECE2019

Lipid profile and cardiovascular risk in psoriatic arthritis

Kostoglou-Athanassiou Ifigenia , Kostopoulos Markos , Athanassiou Lambros , Tsakiridis Pavlos , Athanassiou Panagiotis

Introduction: Psoriatic arthritis (PsA) is a chronic systemic autoimmune disorder. Currently, various biologic agents are administered in PsA patients, improving significantly disease manifestations as well as quality of life. Biologic treatment may have an effect on lipid profile and the cardiovascular risk in the disease.Aim: The aim was to follow-up a group of PsA patients and to evaluate comorbidities, lipid profile and cardiovascular risk and the ef...

ea0049ep275 | Calcium & Vitamin D metabolism | ECE2017

The effect of 1,25(OH)2D3 on interferon i secretion by human mononuclear cells in vitro

Athanassiou Lambros , Nezos Andrianos , Kostoglou-Athanassiou Ifigenia , Mavragani Clio , Athanassiou Panagiotis , Koutsilieris Michael

Vitamin D is a secosteroid hormone known for its skeletal effects. Recently, the extraskeletal effects of vitamin D are under investigation. Vitamin D is thought to exert an immunomodulatory effect, having multiple effects on the immune system. It is known to induce immune tolerance and also to enhance the immune response to bacteria.The aim was to study the effect of 1,25(OH)2D3 on interferon I secretion by human mononuclear cells ...