Endocrine Abstracts

Introduction: Systemic lupus erythematosus is a systemic autoimmune disease, which often necessitates the administration of corticosteroids for its treatment. Cushing’s syndrome is a disorder characterized by the endogenous hypersecretion of cortisol.Aim: The aim was to describe the case of a patient who had systemic lupus erythematosus, was on therapy with corticosteroids and developed Cushing’s syndrome.Case description...

Introduction Severe infection from the SARS-CoV-2 virus is associated with various manifestations, including hematological manifestations. Thrombotic events or a tendency to develop thrombotic events also characterize severe COVID-19 disease and may be related to fatalities. Vitamin D is known to have immunomodulating properties and to enhance the body defense system against invading pathogens and to have immunostimulatory properties as far as the innate immune response is con...

Rheumatoid arthritis is a systemic autoimmune inflammatory disease characterized by severe pain, if left untreated. Primary hyperparathyroidism is a systemic disorder characterized by disordered calcium metabolism leading to increased serum calcium and PTH levels. Primary hyperparathyroidism may be due to the presence of a parathyroid adenoma or parathyroid hyperplasia. The aim was to present a cohort of patients with rheumatoid arthritis who presented with primary hyperparath...

Introduction: Ankylosing spondylitis (AS) is a chronic systemic inflammatory disorder which affects the sacroiliac joints, the axial skeleton, peripheral joints as well as other organs. It develops in young adults causing significant mobility and functional disorders, with associated severe dysfunction or disability. Ankylosing spondylitis has serious adverse effects on the ability to work and quality of life. Biologic agents are used for the treatment of AS, this effect havin...

Introduction: Stress is a known risk factor for the development of Graves’ disease. We have previously described the role of bereavement as an inducing factor for Graves’ disease. Bereavement as an inducing factor for Graves’ disease was shown to affect primarily female patients after the loss of a loved one. However, it appears that other stressful life events may also cause Graves’ disease.Aim: The aim of the study was to describe t...

Introduction: Psoriatic arthritis (PsA) is a chronic systemic autoimmune disorder. Currently, various biologic agents are administered in PsA patients, improving significantly disease manifestations as well as quality of life. Biologic treatment may have an effect on lipid profile and the cardiovascular risk in the disease.Aim: The aim was to follow-up a group of PsA patients and to evaluate comorbidities, lipid profile and cardiovascular risk and the ef...

Vitamin D is a secosteroid hormone known for its skeletal effects. Recently, the extraskeletal effects of vitamin D are under investigation. Vitamin D is thought to exert an immunomodulatory effect, having multiple effects on the immune system. It is known to induce immune tolerance and also to enhance the immune response to bacteria.The aim was to study the effect of 1,25(OH)2D3 on interferon I secretion by human mononuclear cells ...

Tocilizumab is an interleukin-6 receptor antagonist used in the treatment of rheumatoid arthritis (RA). It is known to induce remission and inhibit radiographic progression in RA. Tocilizumab may be administered either intravenously or subcutaneously. Its effect on lipid levels and the cardiovascular risk has not been fully investigated. The aim was to study the effect of tocilizumab i.v. on disease activity, lipid levels and cardiovascular risk in RA patients.<p class="ab...

Introduction: Non-thyroidal illness syndrome or low T3 syndrome is an alteration of thyroid hormone levels which occurs as a reaction to acute disease. It is characterized by low TSH levels and low T3 and T4 levels. It is transient. The severity of its expression may be related to the severity of the acute disease. It affects patients hospitalized for acute disease in the department of medicine or surgery and in the acute care unit.<p class...

Introduction: Primary hyperparathyroidism is nowadays frequently diagnosed due to routine blood calcium measured in the general biochemical profile. Primary hyperparathyroidism may be due to a parathyroid adenoma or parathyroid hyperplasia. Parathyroid adenoma may occur in the area of the parathyroid glands or may be ectopic.Aim: The aim was to describe the differential clinical expression of primary hyperparathyroidism due to an adenoma or hyperplasia i...