Endocrine Abstracts

Introduction: Over the past few years the clinical relevance of serum uric acid level has changed. The elevated serum uric acid level not only impairs the joints and the kidney function but it is also linked with an increased risk of cardivascular diseases. The aim of our study was to examine how bones are affected (change of bone mineral density (BMD), bone metabolism parameters, serum 25-hydroxyvitamin D levels and frequency of fractures) by elevated serum uric acid level.</...

Introduction: Lactose intolerance itself is linked with lower peak bone mass (PBM) and with decreased bone mineral density (BMD) which may decrease further with lactose intolerance associated comorbidities. The aim of our study was to examine how bone metabolic parameters are affected (change of bone metabolism markers, BMD and frequency of fractures) in lactose intolerance which was accompanied by previously diagnosed hyperlipidemia or by hypothyroidism.<p class="abstext"...

Introduction: Polycystic ovary syndrome (PCOS), lactase deficiency, nephrolithisasis and thyroid diseases are considered endemic. The aim of our study was to evaluate which of the above-mentioned diseases affect the most the bone metabolic parameters, bone mineral density (BMD) and the prevalence of bone fractures in fertile aged women.Materials and methods: A total of 92 fertile aged women (32.6±5.2 years) were divided into four groups (23 in each)...

Our aim was to investigate whether pollen-allergy can affect fractures in postmenopausal women. A total of 125 postmenopausal pollen-allergic women (mean age 61.26 yr) were split into four groups: treated neither with H1 histamine receptor (H1R) antagonist nor with inhaled corticosteroid (n=43), treated only with H1R antagonist (n=53), treated both with H1R antagonist and inhaled corticosteroid (n=17), treated only with inhaled corticosteroid (n=12)...

Histamine receptor antagonists seem to have effect on bone metabolism according to previous studies. We investigated the bone turnover in allergic children who were treated with H1 hisztamin receptor (H1R) antagonists.The biochemical bone turnover markers [β-CrossLapps (β-CTx), osteocalcin (OCN), β-CTx/OCN ratio], parathyroid hormone (PTH) and the 25-OH-vitamin D3 were determined in 37 H1R antagonist treated multiplex allergic c...

Background: Despite receiving biochemically adequate levothyroxine replacement, many patients with primary hypothyroidism suffer from persistent symptoms and a reduced quality of life (QoL). The underlying causes of this phenomenon are not fully understood, but psychological factors, autoimmune inflammation, and variations in thyroxine conversion have all been suggested as potential contributors. At this time, however, there is no consensus on the root cause.<p class="abst...

A 32-year-old women initially presented with recurrent kidney stones and was found to have nephrocalcinosis. She was found to normocalcaemic but hypercalciuric, with a plasma ionized calcium at upper-limit of normal and a PTH in lower normal range. One year later, during the first trimester of a pregnancy, she presented with severe hypercalcaemia, hypercalciuria and suppression of PTH. Extensive investigations for causes of hypercalcaemia excluded hyperparathyroidism, other en...