Searchable abstracts of presentations at key conferences in endocrinology

ea0035p84 | Bone and Osteoporosis | ECE2014

Teriparatide treatment in a patient with severe pregnancy related osteoporosis

Polat Burcak , Evranos Berna , Aydin Cevdet , Ersoy Reyhan , Cakir Bekir

Introduction: Pregnancy or lactation related osteoporosis (PLO) is very rare. It usually occurs in the third trimester or in the early post partum period and manifestations are severe back pain and loss of height due to vertebral fractures. Its etiology is not well understood. Classical treatment is cessation of lactation, calcium and Vit-D supplementation and biphosphanates in chosen cases. All osteoporosis drugs are approved mainly for post-menouposal osteoporosis a...

ea0049ep1152 | Female Reproduction | ECE2017

Does radioactive ıodine therapy affect fertility?

Evranos Ogmen Berna , Faki Sevgul , Burcak Polat Sefika , Bestepe Nagihan , Ersoy Reyhan , Cakir Bekir

Introduction: Thyroid carcinoma is common in young women. Radioactive iodine (RAI) therapy has been confirmed as a useful treatment in the management of differentiated thyroid carcinoma (DTC). For women with DTC, the effect of RAI therapy on gonadal and reproductive function is an important consideration. We aimed to evaluate effects of RAI therapy on ovarian function.Method: Women younger than 40 years old and diagnosed with thyroid cancer that required...

ea0041gp43 | Bone & Calcium Homeostasis (1) | ECE2016

Evaluation of preoperative ultrasonographic and biochemical features of patients with aggressive parathyroid disease: Is there any reliable predictive marker?

Cakir Bekir , Burcak Polat Sefika , Kilic Mehmet , Ozdemir Didem , Aydin Cevdet , Sungu Nuran , Ersoy Reyhan

Introduction: Parathyroid cancer (PC) is rare accounting for <1% of all presentations. Tumors that demonstrate these atypical features and do not fulfill criteria for carcinoma can be classified as atypical adenomas (APA). Herein we aimed to evaluate the clinical and biochemical features of the patients with an atypical parathyroid adenoma or carcinoma and compare it with benign parathyroid adenomas.Method: Twenty-eight patients who were operated for...

ea0041ep301 | Clinical case reports - Pituitary/Adrenal | ECE2016

Acromegaly in a male patient with Kleinfelter syndrome

Burcak Polat Sefika , Bestepe Nagihan , Topaloglu Oya , Bal Ercan , Ersoy Reyhan , Cakir Bekir

Introduction: Klinefelter syndrome is known as the set of symptoms that result from two or more X chromosomes in males. There is no known association of this syndrome with GH hypersecretion. The most remarkable symptom is gigantism and it can also be observed in androgen deficient states as such as the Klinefelter syndrome and some more genetic syndromes such as the Sotos syndrome, the Marfan syndrome, the homocystinuria, and the fragile X-syndrome. Herein we presente...

ea0037ep771 | Pituitary: clinical | ECE2015

Association of hormonal changes with disease severity and mortality rate in critically ill patients

Cuhaci Neslihan , Ogmen Berna , Doger Cihan , Polat Burcak , Izdes Seval , Ersoy Reyhan , Cakir Bekir

Introduction: Endocrinological and metabolic changes can occur in critically ill patients, which may affect the prognosis and outcome. The hypothalamic–anterior–pituitary axis (HPA) plays a crucial role in the endocrine regulation of metabolic and immunological homeostasis. In this prospective study, we evaluated the pituitary–adrenal–gonadal–thyroid axis in the adult Intensive Care Unit (ICU) patients,their outcome, the association between these hormo...

ea0037ep1173 | Clinical Cases–Pituitary/Adrenal | ECE2015

Longest survival with central diabetes insipidus; more than 30 years without and 25 years with desmopressin treatment

Ozdemir Didem , Polat Sefika Burcak , Polat Yunus Halil , Ersoy Reyhan , Cakir Bekir

Introduction: Diabetes insipidus (DI) is a disease characterized by excessive thirst, polydipsia and excess diluted urine caused by insufficiency of antidiuretic hormone or renal resistance to its effect. Although it is generally a benign condition, severe hypernatremia and hypertonicity may cause death if water loss is not compensated.Case report: A 72-years-old man admitted to our clinic for routine control. In medical history, he told that when he was...

ea0035p147 | Calcium and Vitamin D metabolism | ECE2014

Hypoparathyroidism and celiac disease a rare autoimmune disease combination

Ogmen Berna , Cuhaci Neslihan , Polat Burcak , Aydin Cevdet , Ersoy Reyhan , Cakir Bekir

Case: A 30-year-old man with hypoparathyroidism has been treated with calcitriol and calcium for 2 years, admitted hospital with persisting diarrhea. An endoscopic operation is planned. But when he was waiting for this examination as outpatient condition, he had a convulsion and had been taken in hospital by parents. Initial laboratory analyses revealed that he was hypocalcemic (total calcium of 6 mg/dl) and parathormone (PTH) 8 pg/ml, phosphorus 5.7 mg/dl, and magnesium 2 mg/...

ea0035p374 | Diabetes (epidemiology, pathophysiology) | ECE2014

New onset T1DM after vaccination for measles: Coincidence or consequence?

polat Burcak , Aydin Cevdet , Evranos Berna , Cuhaci Neslihan , Ersoy Reyhan , Cakir Bekir

Introduction: Viruses and virus-induced lymphokines may have an important role in the pathogenesis of autoimmunity. The occurrence and significance of autoimmune manifestations after the administration of viral vaccines remain controversial. Herein we have represented a case who developed type 1 diabetes 1 month after vaccination for measles in military.Case: A 25-year-old male patient admitted to our clinics with the complaints of polyuria, poydipsia, a...

ea0035p447 | Diabetes complications | ECE2014

Prolonged cerebellar ataxia after: severe hypoglycemic attack in a patient with T1DM: a rare but disturbing sequela

Polat Burcak , Aydin Cevdet , Evranos Berna , Cuhaci Neslihan , Ersoy Reyhan , Cakir Bekir

Introduction: Hypoglycemia is common in people with diabetes who aim to achieve strict glucose control. The neurologic manifestations of hypoglycemia are mostly reversible and includes behavioral changes, difficulty in concentration, confusion, loss of fine motor functions, and seizures. Herein we have presented a case who was pregnant and experienced severe hypoglycemia which led to permanent ataxia.Case: A 26-years-old female patient was brought to our...

ea0035p894 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

‘High dose hook effect' in a patient with invasive giant prolactinoma

Ogmen Berna , Aydin Cevdet , Polat Burcak , Cuhaci Neslihan , Altundal Naci , Ersoy Reyhan , Cakir Bekir

Background: Prolactin secreting pituitary adenomas (prolactinomas) is the most common pituitary adenoma. The magnitude of prolactin secretion in prolactinomas is usually proportionate to the tumor’s size. Invasive giant prolactinoma is a large prolactinoma (>4 cm in dimension) presenting with serum prolactin levels of >1000 ng/ml and mass related clinical symptoms. Giant prolactinoma is rare and usually presents in men.Case report: A 52-year...