Searchable abstracts of presentations at key conferences in endocrinology

ea0063p632 | Interdisciplinary Endocrinology 1 | ECE2019

Alleviation of Autoimmune phenomena in Hashimoto’s thyroiditis after Thyroidectomy: Is this an additional surgical indication?

Panchangam Ramakanth Bhargav , Sabaretnam M , Chakrapani B , Ramesh B , Rajesh B

Introduction: Hashimoto’s thyroiditis (HT) is one of the commonest endocrine disorder. Often, HT is associated with a plethora of autoimmune co-morbidities (AIC) such as vitiligo, arthitides, pernicious anaemia, skin allergy, thrombocytopenia, addison’s disease, type 1 diabetes, celiac disease, eosinophilia etc., The etiology of these AIC in HT is enigmatically idiopathic and hypothesized to be autoimmune in origin. Many studies suggests that thyroid specific antibod...

ea0063p633 | Interdisciplinary Endocrinology 1 | ECE2019

Is Hashimoto’s encephalopathy Reversible with Surgical Thyroidectomy: A South Indian experience

Panchangam Ramakanth Bhargav , Mayilvaganan Sabaretnam , Bangariahgari Chakrapani , Rajesh B , Ramesh B

Introduction: Hashimoto’s thyroiditis (HT) is one of the frequent endocrine disorder. Clinical picture in Hashimoto’s thyroiditis is predominantly due to associated hypothyroidism and/or goiter related neck complaints. Rarely, HT can be associated with recurrent encephalopathy characterized by seizures, amnesia and comatose episodes. The etiology of this Hashimoto’s encephalopathy (HE) is enigmatically idiopathic and hypothesized to be autoimmune in origin. The ...

ea0056p903 | Endocrine Disruptors | ECE2018

Correlational evaluation of inflammatory biomarkers in polycystic ovarian disease: a case control study

Gayathri G , Rajesh B , Ramesh B , Vignesh D , Venkateshwara Reddy M , Rajkiran Reddy B , Chakrapani B , Bhargav PRK

Introduction: Contrary to the high prevalence of polycystic ovarian syndrome (PCOS) amongst reproductive age group women, there is disproportionate uncertainity over its etiopathogenesis. Substantial evidence suggests immunological-inflammatory role in causing this endocrine disorder. In this context, we set out study the role of inflammatory biomarkers in PCOS.Material and methods: This prospective case-control study was conducted on PCOS patients diagn...

ea0056p1007 | Endocrine Disruptors | ECE2018

Association of Pro-inflammatory cytokines and Benign Thyroid nodules: A prospective case-control study

Rajkiran Reddy B , Ramesh B , Rajesh B , Vighnesh D , Gayathri G , Venkateshwar Reddy M , Chakrapani B , Bhargav PRK

Introduction: Nodular thyroid disease (NTD) is one of the commonest endocrine disease with incidence ranging from 5–30% in various populations Worldwide. They often require surgery for indications such as pressure symptoms or size related reasons. The natural history and etiopathogenesis are largely unclear except in few endemic regions. Immunomodulatory role has often been implicated in their pathogenesis. In this context, we set out study the association between Pro- in...

ea0056ep91 | Environment, Society and Governance | ECE2018

Selfie driven thyroid disease leads (SET): a study on a unique phenomenon from Surgical Endocrinology Department

Panchangam Ramakanth Bhargav , B Chakrapani , B Ramesh , B Rajesh , M Venkateshwara Reddy , D Vignesh , N Vimala Devi , G Gayathri

Introduction: Taking a photograph of self alone or with a group called Selfie, has become modern day rage with spurt in smart phone technology. It has catapulted from a hobby in to psychiatric ailment, especially amongst teens and young adults. Though, it is considered as a psychiatric aberration keeping them aloof from social interactions, we observed an inadvertent advantage in this habit. In this context, we present some intriguing findings through this study.<p class="...

ea0041gp141 | Paediatric Endocrinology &amp; Development | ECE2016

Genomics and phenomics of Hashimoto’s thyroiditis and dyshormonogenesis in hypothyroid children of South India

Ramakanth Bhargav Panchangam , Ramesh B

Background: Dyshormonogenetic goiter and Hashimoto’s thyroiditis are amongst the commonest causes of hypothyroidism in children and adolescents Worldwide. But, the genetic basis and their hypothyroid phenotypes are under-reported, especially from developing countries. In this context, we screened for dyshormonogenetic mutations in hypothyroid children with dyshormogenetic goiter (DH) and Hashimoto’s thyroiditis (HT).Material and methods: In thi...

ea0063p355 | Thyroid 1 | ECE2019

An ununsual thyroid cause for Pyrexia of unknown origin (PUO)

Panchangam Ramakanth Bhargav , Chakrapani B , Sabaretnam M , Ramesh B , Rajesh B

Introduction: Granulomatous thyroiditis (GT) is one of the various types of autoimmune thyroiditis. It usually occurs in women of reproductive age in perigestational period. Clinical picture in is predominantly painful goiter with radiating pain to ears with low grade fever lasting for few days, sometimes associated with mild hyper or hypothyroidism. The treatment is symptomatic and supportive with no curative option. There are meagre anecdotal reports of thyroidectomy role fo...

ea0037ep1027 | Thyroid (non-cancer) | ECE2015

Association between thyroid specific genotypic variation and phenotypic expression of dyshormogenetic goitre and Hashimoto's thyroiditis in children and adolescents: a South Indian experience

Ramesh B , Aparna Verma B , Vijayaraghavan R , Ramakanth Bhargav P , Rajesh B

Background: Thyroid disorders are the commonest endocrine disorder after diabetes in most of the populations worldwide. Though, hypothyroidism is extremely common in children, there is acute scarcity of genetic studies leading to improper screening and treatment protocols in developing countries. The aim of this ambitious study was to screen for NIS, DUOX2 and TPO mutations in south Indian children and adolescent patients with dyshormogenetic goiter (DH) and Hashimoto’s t...

ea0003oc31 | Metabolism | BES2002

An interaction between ghrelin and a species of high-density lipoprotein

Beaumont N , #TM-M|#Tan|# , Skinner V , Ramesh B , Byrne D , Mikhailidis D , Bouloux P , Srai S , Vanderpump M

Ghrelin is an acylated peptide hormone that is expressed by a variety of tissues including the stomach, hypothalamus and kidney. Ghrelin produces a range of effects, including stimulating the release of growth hormone from the pituitary gland, and inducing feeding and obesity.The effects of some hormones can be altered by interactions with other proteins; so the aim of this project was to screen plasma for proteins that can bind ghrelin, as part of an i...

ea0056p208 | Calcium &amp; Vitamin D metabolism | ECE2018

A Curious phenomenon of Post radioiodine therapy induced hypocalcemia in Graves’ disease: Case series

Panchangam Ramakanth Bhargav , Ramesh B , Rajesh B , Vimaladevi N , Rajkiran Reddy B , Venkateshwara Reddy M , Vignesh D , Chakrapani B

Introduction: Graves’ disease (GD) is often treated with radioiodine therapy for cure. While, post external irradiation and post-radioiodine therapy (RAI) induced hyperparathyroidism after many years of latency is a well known phenomenon, there are only anectodal reports of post-radioiodine hypocalcemia. The factors contributing to this are poorly understood. In this context, we evaluated our own series to look deeper in to this issue.Material and m...