Endocrine Abstracts

Thyroid cancer is the most common endocrine malignancy, and accounts for between 5 and 10% of thyroid nodules biopsied in endocrine services. As per the Global Cancer Observatory, the incidence of thyroid cancer in Bahrain is 2.12 cases per 100 000 people, which is less than the neighbouring countries of Saudi Arabia and Kuwait. The purpose of the study is to investigate the relationship between thyroid cancer and obesity in Bahrain, where 28.9% of males and 38.2% of females a...

Objective: We sought to assess the knowledge of adrenal insufficiency among undergraduate healthcare students and pharmacy staff.Methods: We undertook a cross-sectional UK-wide survey of final year undergraduate student knowledge of AI before and after an online educational intervention. Universities were recruited through the Council of Medical Schools, Council of Pharmacy and Dean of Health Council, whereby surveys wer...

Contexte: Acromegaly is a rare disease, usually caused by hypersecretion of growth hormone (GH) by a pituitary adenoma and very rarely by ectopic secretion of GHRH. It remains a serious disease reduces life expectancy because of its cardiovascular and metabolic impact.Objective: The objective of this study is to report the glycemic profile in patients followed for acromegaly in the endocrinologic center of CHU Med VI of Marrakech.P...

Contexte: Kallmann syndrome is a rare genetic disease which can affect both men and women. It combines hypogonadotropic hypogonadism which characterised by a failure to start or to fully complete puberty naturally; olfactory disorders such hyposmia or anosmia, impaired color vision, deafness, unilateral or bilateral renal aplasia and midline anomalies.Objective: We report a case of this rare syndrome, responsible of delayed puberty view of infertility.</...

Case history: We present the case of a 64 year old man with an incidental finding of pituitary macroadenoma (1.1×0.8×0.5 mm). He had a past medical history of obstructive sleep apnoea, asthma, osteoarthritis, hypertension, retinal detachment and cataract.Investigations: Blood tests.Results and treatment: Pituitary function tests showed markedly elevated prolactin 4272 mIU/L (86–324), elevated free tri-iodothyronine (...

Introduction: Growth hormone deficiency is a rare cause of stunting; its diagnosis is often delayed by severe growth retardation; confirmed by non-response to GH stimulation tests (insulin and glucagon-propranolol test). The absence of early diagnosis and treatment can lead to severe growth retardation. We propose to determine the prevalence of different etiologies of growth hormone deficiency in patients followed for a saturo-weight delay at the Arrazi Hospital, Medical Unive...

Introduction: Necrosis of the nasal pyramid is mainly of traumatic origin, among the other possible causes, those induced by systemic diseases, in particular Wegener’s granulomatosis…We report a case of necrosis of the nasal pyramid secondary to prolonged intubation in a type 1 diabetic.Observation: Patient T.T, 28 years old, followed for a poorly balanced type 1 diabetes, admitted to a blood clot in a table of diabetic ketoacidosis. The patie...

Introduction: Neurofibromatosis type 1 (NF1) is the most common autosomal dominant disease. The endocrine manifestations of NF1 are represented by pubertal abnormalities and pheochromocytoma. We report a case.Observation: Mr. G.A, age 28, consulling for a grade 2 HTA evolving for 3 years. The anamnesis notes paroxysmal crises made of Ménard triad. The exam notes a correct blood pressure, 18 coffee latte tasks, lentiginous tasks. Two neurofibromas of...

A 26-year-old Chinese male with autism spectrum disorder and mental retardation, was referred to start insulin therapy for uncontrolled diabetes mellitus (DM) (HbA1c: 9%; C-peptide: 1.75 ng/ml; anti-GAD AB: negative) treated with oral antidiabetic drugs since 2012.Clinical examination revealed a tall man with overweight and truncal obesity in light of his ethnicity. We withheld facial dysmorphism with hypertelorism, scarce facial hair, and clinodactyly. ...

Introduction: Struma ovarii (SO) is a rare ovarian teratoma characterized by the presence of thyroid tissue in >50% of the tumour. Malignant transformation is rare and defined by the same histological criteria as for thyroid cancer. There is few data on the literature and treatment is controversial. The objective of this study was to describe the clinical, pathologic and treatment characteristics of women diagnosed with SO in our centre.Methods: Retr...