Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep260 | Calcium & Vitamin D metabolism | ECE2017

How to differentiate primary hyperparathyroidism with D hypovitaminosis from secondary hyperparathyroidism due to D hypovitaminosis?

Gatu Alina-Andreea , Velicescu Cristian , Preda Cristina , Vulpoi Carmen , Mogos Simona , Mogos Voichita , Zaharia Valentin , Aancute Adrian , Branisteanu Dumitru

Background: D hypovitaminosis and primary hyperparathyroidism frequently coexist. Secondary hyperparathyroidism reactive to D hypovitaminosis is difficult to be differentiated from primary hyperparthyroidism.Aims: To differentiate patients with D hypovitaminosis and secondary hyperparathyroidism.Materials and methods: Prospective study involving 71 patients admitted in our department for 1 year with the initial diagnosis of primary...

ea0049ep838 | Clinical case reports - Pituitary/Adrenal | ECE2017

A rare association of autoimmune diabetes insipidus and hypophysitis with partial pituitary insufficiency

Matei Livia , Stefaroi Corina , Mogos Simona , Branisteanu Dumitru

We present the case of a 40 year old man presenting at first consultation an ‘idiopathic’ fast-onset and severe polyuro-polydipsic syndrome (diuresis of 10 l/24 hours, with urine osmolality of less than 50 mOsm/kg and urine gravity lower than 1001). Clinical examination showed pallor and decreased pilosity at an asthenic patient with limited lesions of vitiligo and loss of libido. Water deprivation test showed the persistence of excretion of highly diluted amounts of...

ea0014p438 | (1) | ECE2007

Cutaneous modifications suggestive for Cushing’s syndrome induced by topical corticoid application

Mogos Simona , Branisteanu Dumitru , Zbranca Anca , Zbranca Eusebie , Mogos Voichita

Topical application of corticosteroids is frequently used in the therapy of various dermatological diseases due to their antiinflammatory and immunsuppressive effects. Systemic pharmacological levels of glucocorticoids lead, on the other hand, to Cushing syndrome, i.e. significant modifications of intermediary metabolism, body composition, bone mass, haematolymphopoietic system and, last but not least, to skin modifications: purple striae, petechiae, infections. We describe a ...

ea0026p154 | Male reproduction | ECE2011

Erectile dysfunction in endocrine patients (pituitary diseases)

Mogos Simona Juliette , Vulpoi Camen , Ananie Teodora , Mogos Voichita , Zbranca Eusebie

Aim of the study: Assessing prevalence and severity of erectile dysfunction in patients with pituitary diseases.Materials and methods: International Index of Erectile Function (IIEF) and Sexual Health Inventory for Men (SHIM) questionnaires were used to assess erectile dysfunction (ED) in 83 patients having pituitary diseases (31 patients had hypopituitarism, 11 diabetes insipidus, 10 prolactinomas, 11 nonfunctional adenomas, 16 operated acromegaly, 4 GH...

ea0022p210 | Clinical case reports and clinical practice | ECE2010

Two rare genetic causes of aberrant growth: Robinow syndrome with partial GH deficiency and dwarfism and Simpson-Golabi-Behmel syndrome with gigantism

Branisteanu Dumitru , Repede Ionut , Novac Roxana , Turliuc Serban , Mogos Simona , Turliuc Dana , Mogos Voichita

We describe two very rare genetic diseases characterized by particular physical features and deviation from normal growth. The first patient, CM, was admitted for delayed growth (113 cm at 8 years of age, -3 S.D.). The child had short lower arms with small hands and clinodactyly of the fifth finger. He had round widely spaced eyes with long eyelashes, a flat profile and prominent forehead, short upturned nose, misaligned teeth and gum hypertrophy. We diagnosed a...

ea0020p43 | Adrenal | ECE2009

Iatrogenic Cushing’s syndrome induced by topical corticoid application in child and adult

Branisteanu Dumitru , Turliuc Serban , Veliaj Blenda , Mogos Simona , Zbranca Eusebie , Repede Ionut , Aancute Adrian , Mogos Voichita

Topical application of corticosteroids is frequently used in the therapy of dermatological diseases due to their anti-inflammatory and immunosuppressive effects. On the other hand, when reaching pharmacological levels, exogenous corticoids frequently lead to complete Cushing syndrome, including skin modifications, irrespective of the route of administration. We describe four cases of iatrogenic Cushing’s syndrome triggered by topical application of corticoids. The first t...

ea0016p769 | Thyroid | ECE2008

The influence of chronic GH excess upon thyroid gland morphology evaluated by ultrasound

Buzduga Catalin , Ananie Teodora Emiliana , Mogos Simona , Zbranca Eusebie , Galesanu Corina , Mogos Voichita , Branisteanu Dumitru D

It is known that thyroid pathology is generally more frequently found in women than in men. The somatotroph axis stimulates skeleton growth, but also the development of smooth tissues, including the thyroid gland. We investigated the effect of chronic GH excess upon ultrasound-evaluated (7.5 MHz linear probe) thyroid gland morphology of 74 patients (40 women şi 34 men) diagnosed with acromegaly. When compared to mean thyroid volume of age- and sex-matched non-acromegali...

ea0014p478 | (1) | ECE2007

Primary hyperparathyroidism during pregnancy – case report

Mogos Voichita , Mogos Simona , Onofriescu Mircea , Cotea Elena , Tarcoveanu Eugen , Florea Niculina , Zbranca Eusebie

Until 2002 less than 200 cases of primary hyperparathyroidism identified during pregnancy were reported. We present a case of primary hyperparathyroidism discovered during pregnancy in a 28-year-old woman. The disease was suspected due to a hypercalcemia discovered during a routine blood assessment during pregnancy (calcium=11 mg/dl, phosphorus=2.4 mg/dl). The patient was investigated in the Clinic of Endocrinology and the diagnosis of primary hyperparathyroidism was made on b...

ea0090p707 | Pituitary and Neuroendocrinology | ECE2023

Acromegaly and its ophthalmic, neurological and psychiatric complications

Cristiana Istrate Andra , Christina Ungureanu Maria , Leustean Letitia , Juliette Mogos Simona , Bilha Stefana , Florescu Alexandru , Preda Cristina

Introduction: Acromegaly is a rare, complex condition that throughout its evolution affects the body on numerous levels, especially if inappropriately managed. Some of the complications it develops over time are ophthalmic, neurological and psychiatric.Aim: The aim is to asses the impact of long-term acromegaly on the eye, nervous system and mental health of previously diagnosed patients.Patients and method: 90 patients’ recor...

ea0049ep213 | Bone & Osteoporosis | ECE2017

Primary hyperparathyroidism: hormonal profile and risk of complications

Gatu Alina-Andreea , Velicescu Cristian , Preda Cristina , Mogos Voichita , Vulpoi Carmen , Mogos Simona , Zaharia Valentin , Aancute Adrian , Branisteanu Dumitru

Background: Vitamin D deficiency is frequently associated with primary hyperparathyroidism, but the impact of this association on disease evolution and complications is ill defined. Aims: to assess the role of vitamin D status on the metabolic profile and spectrum of complications at patients with primary hyperparathyroidism.Materials and methods: Transversal study involving 42 patients with primary hyperparathyroidism submitted to parathyroidectomy. We ...