Searchable abstracts of presentations at key conferences in endocrinology

ea0064027 | Catastrophic antiphospholipid syndrome with bilateral adrenal hemorrhage: a case report | BES2019

Catastrophic antiphospholipid syndrome with bilateral adrenal hemorrhage: a case report

Lucrezia De Marchi , Jeroen M K de Filette , Bastiaan Sol , Corina E Andreescu , Rastislav Kunda , Peter Buydens , Brigitte Velkeniers

Background: Adrenal insufficiency is a rare but potentially life threatening complication of the antiphospholipid antibody syndrome (APS). The adrenal gland is the most commonly involved endocrine organ with adrenal insufficiency reported in 0.4% of APS cases. Adrenal failure more often follows other thromboembolic manifestations of APS.Case report: We report a 25-year-old male with systemic lupus erythematosus (SLE) with antiphospholipid syndrome (tripl...

ea0064038 | Pheochromocytoma-induced Takotsubo syndrome: when you hear hoofbeats, it may be a zebra! | BES2019

Pheochromocytoma-induced Takotsubo syndrome: when you hear hoofbeats, it may be a zebra!

Jerrold Spapen , Jeroen de Filette , Bastiaan Sol , Aan Kharagjitsing , Brigitte Velkeniers , Bert Bravenboer , Stijn Lochy , Corina Andreescu

Pheochromocytoma is a rare catecholamine-secreting tumor with variable clinical manifestations. A possible cardiac presentation is acute left ventricular wall motion abnormality in the heart also known as the Takotsubo syndrome. Takotsubo stress cardiomyopathy was first described in 1990 in Japan and current knowledge remains limited. We report a case of pheochromocytoma-induced Takotsubo syndrome. A 43-year-old woman acutely developed nausea, severe chest pain, and dyspnoea d...

ea0079019 | Abstracts | BES2021

COVID-19 & Cushing’s disease in a patient with ACTH-secreting pituitary carcinoma

Jeroen M.K. de Filette , Bastiaan Sol , Gil Awada , Corina E. Andreescu , David Unuane , Duc Nam Nguyen , Sandrine Aspeslagh , Jan Poelaert , Brigitte Velkeniers , Bert Bravenboer

Background : The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is of an unprecedented scale, with an ever-growing impact on healthcare systems. The clinical presentation of coronavirus disease 2019 (COVID-19) is diverse, ranging from asymptomatic illness to respiratory failure requiring admission to the intensive care unit (ICU). Risk factors for severe presentation include old age, male gender, underlying comorbidities such as metabolic syndr...

ea0081p159 | Pituitary and Neuroendocrinology | ECE2022

What is the relevance of he systematic use of gadolinium (Gd) during the MRI follow-up of non-functioning pituitary adenomas (NFPAs)?

Villemaire Axel , Mouly Celine , Solange Grunenwald , Adam Gilles , Darcourt Jean , Patsoura Sofia , Roques Margaux , Catalaa Isabelle , Fayolle Helio , Cognard Christophe , Sol Jean-Christophe , Caron Philippe , Fabrice Bonneville

Objective: To compare the performances of the coronal contrast-enhanced T1-weighted (ceT1-w) and T2-weighted (T2-w) sequences, for the diagnosis of progression during the MRI follow-up of NFPAs.Materials and methods: 106 patients who had at least two MRIs for the follow-up of NFPA were retrospectively included. The largest diameter of the adenomas was measured on coronal ceT1-w and separately on T2-w sequences for all the MRIs of the follow-up, and by 2 ...

ea0063p712 | Pituitary and Neuroendocrinology 2 | ECE2019

Does silent pituitary neuroendocrine tumors show lower specific adenohypophyseal gene hormone expression than functioning ones?

Torregrosa Maria Eugenia , Garcia-Martinez Araceli , Lopez-Munoz Beatriz , Sanchez-Barbie Angel , Camara Rosa , Lamas Cristina , Fajardo Carmen , Serrano Sol , Pico Antonio

Introduction: Pituitary Neuroendocrine Tumor (PitNET) subtypes present functioning and silent variants but the silencing mechanisms are still unknown. One of the possible hypotheses could be a decrease in the expression of the specific adenohypophyseal hormone genes. The aim of the present study was to analyze the expression of adenohypophyseal hormone genes in a series of PitNETs, in order to evaluate differences between functioning and silent PitNET subtypes, taking into acc...

ea0041ep1012 | Thyroid (non-cancer) | ECE2016

Central/Peripheral vascularization and resistance index at Doppler ultrasound examination of thyroid nodules: are they useful to differentiate between benign and malignant pathology?

Pacenza Nestor , Rosmarin Melanie , Blan Evelin , Serrano Sol , Cejas Claudia , Sforza Noelia , Serrano Leonardo , Campero Adriana , Frid Santiago , Faingold Maria Cristina , Brenta Gabriela

Thyroid Doppler ultrasound (TDUS) is highly used in the evaluation of thyroid nodules (TN). Malignant thyroid pathology has been more frequently associated with central vascularization of such nodules. There is controversy regarding the usefulness of the Resistance Index (RI) in the assessment of TN.Our aim was to analyze the utility of vascularization characteristics and RI at TDUS in the distinction of benign and malignant TN.Mat...

ea0011p904 | Thyroid | ECE2006

Modifications in the frequency of presentation and the TNM stage at diagnosis of thyroid carcinoma in the last decade in Valencia (Spain)

Yanini J , Casañ R , García K , Jover A , Gómez M , Solá E , Morillas C , Peña H , Muñoz ML , Hernández A

Aims: The aim of the present study was to evaluate the relative frequency of histological categories of thyroid malignant neoplasms. Another aim was to evaluate the TNM stage differentiated thyroid carcinoma (DTC) at the time of initial presentation in Valencia Community (Spain).Methods: Histopathology and TNM stage thyroid carcinomas diagnosed of thyroid carcinoma diagnosed between 1998 and 2005 in our endocrinology service, were recorded.The sample was...

ea0081ep194 | Calcium and Bone | ECE2022

Vitamin D deficiency in the type 2 diabetic population of Northern Gran Canaria Island: Still highly prevalent but supplementation is on the rise

Hernandez-Lazaro Alba , de Leon-Durango Ricardo , Kuzior Agnieszka , Acosta-Calero Carmen , Arnas-Leon Claudia , del Sol Sanchez-Bacaicoa Maria , Garcia-Alamo Debora , Martin-Perez Marta , Gonzalez-Diaz Paula , Martin Francisco Javier Martinez

Introduction: Vitamin D deficiency is associated with higher risk of severe COVID-19, and type 2 diabetic patients are a vulnerable group. We described an alarming rate of vitamin D deficiency (around 80.0% with plasma calcifediol <30 ng/ml) in unsupplemented type 2 diabetes patients during the 2020 spring lockdown and the following winter in Northern Gran Canaria. There is an increasing awareness of this problem, both in family physicians and the general population, and t...

ea0014p226 | (1) | ECE2007

Frequency of hypogonadism in males with type 2 diabetes and its relation with erectile dysfunction and obesity

García-Malpartida Katherinne , Casañ-Fernández Rosa , Yanini-García Jesús , Jover-Fernández Ana , Gómez-Balaguer Marcelino , Solá-Izquierdo Eva , Morillas-Ariño Carlos , Hernández-Mijares Antonio

Introduction: The aim of our study was to determine the frequency of hypogonadism (H) in males with type 2 diabetes (T2D) and its relation with erectile dysfunction (ED) and obesity.Methods: We studied 107 diabetic males who came successively to an Endocrine consultation. The presence of H was determined by total testosterone (T) with an immunofluerescence method and free testosterone (fT) calculated with Vermeulen’s equation, defining H if T<2 ...