Searchable abstracts of presentations at key conferences in endocrinology

ea0090ep626 | Endocrine-related Cancer | ECE2023

Large bilateral adrenal masses: interest of plasma LDH measurement to detect adrenal lymphoma

Tauveron-Jalenques Urbain , Ravinet Aurelie , Guieze Romain , Brusseau Valentin , Tournilhac Olivier , Olivier Bay Jacques , Tauveron Igor

Large adrenal masses are strongly suggestive of malignancy. Nevertheless, bilateral adrenal masses are less common (around 20% of incidental adrenal lesions). Metastases and lymphoma are more frequent (especially when aging), and not so easy to differentiate on CT or MRI. Simple biological markers, such as plasma LDH or beta2microglobulin, could help.Case report: A 69-year-old patient was admitted for abdominal pain with progressive lethargy. Abdominal C...

ea0022p85 | Bone/Calcium | ECE2010

Giant mediastinal parathyroid adenoma, a rare cause of severe acute hyperparathyroidism

Maqdasy Salwan , Desbiez Francoise , Robu Elena , Batisse Marie , Roche Beatrice , Chadeyras Jean Baptiste , Tauveron Igor

Introduction: Ectopic parathyroid adenoma is a rare cause of primary hyperparathyroidism, it accounts for 10% of parathyroid adenomas.Observation: A 56 years old man with no past medical history developed sudden acute renal failure after few weeks of fatigability, polydypsia and emesis. Hypercalcemia of 4.20 mmol/l (2.2–2.5 mmol/l), serum creatinine of 306 mmol/l, hypophospatemia 0.72 mmol/l (0.80–1.5 mmol/l) and high alkaline phosphatase 205 I...

ea0022p432 | Endocrine tumours &amp; neoplasia (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Unexplained hypoxemia in a patient with carcinoid syndrome

Pauline Presumey , Catherine Longuet , Claire Dauphin , Francoise Desbiez , Salwan Maqdasy , Laurene Charra , Marie Batisse , Igor Tauveron

Introduction: The carcinoid heart disease is an uncommon valvular heart disease that may occur in carcinoid syndrome.Valvulopathy is reported in 50% to 70% of patients of carcinoid syndrome, due to the release of serotonin secreted by metastatic cells in the liver, reaching directly right side of heart. The left side is preserved because of inactivation of serotonin by lung parenchyma. Hypoxemia is an unusual presentation of the carcinoid heart disease.C...

ea0020p191 | Endocrine tumours and neoplasia | ECE2009

Clinical features and outcome of thyroid lymphoma: the Auvergne registry

Roche Beatrice , Solmon Caroline , Robu Elena , Desbiez Francoise , Thieblot Philippe , Tauveron Igor

Introduction: Thyroid lymphoma is a rare thyroid disease, occurring mostly in the elderly. We report a series of 13 cases from a single centre.Material and methods: Among our regional registry (1294 cases of thyroid cancer), we report 16 cases of thyroid lymphoma (with sufficient data on follow up for 13).Results: Mean age was 68.3 years (range 38–85) and included 12 women for 1 man. Nine patients also presented with Hashimoto...

ea0016p790 | Thyroid | ECE2008

A case of thyroid abscess due to piriform sinus fistula complicated by hyperthyroidism

Marie Batisse , Frederic Somda , Fancoise Desbiez , Thierry Mom , Philippe Thieblot , Igor Tauveron

Acute suppurative thyroiditis is a rare disease because thyroid gland is highly resistant to infection. The most common predisposing factor is the presence of a piriform fistula. We report an unusual case of hyperthyroidism caused by AST.A 27-year-old woman was admitted to our hospital because she presented a painful swelling in the left thyroid gland with fevers. Laboratory test showed a white leukocyte count of 14 000/μl, a CRP level of 251 mg/l, ...

ea0014p293 | (1) | ECE2007

Which prognosis criteria for thyroid anaplastic carcinoma?

Larroumets Guillaume , Somda Frederic , Roche Beatrice , Dejax Catherine , Desbiez Francoise , Kwiatkowski Fabrice , Thieblot Philippe , Tauveron Igor

The prognosis of thyroid anaplastic carcinoma is poor. Yet can prognosis criteria change the therapeutic options?Method: From a series of 26 cases from a single group recorded between 1990 and 2006, we analyzed the outcome after treatment based on surgery, radio and chemotherapy and looked for prognosis criteria.Results: All but one patients died with a mean survival of 273 days (median survival of 130 days). Over 50% of patients h...

ea0063p682 | Pituitary and Neuroendocrinology 2 | ECE2019

Assessment of oro-dental manifestations in a series of acromegalic patients, the AcroDent study

Roumeau Sylvain , Thevenon Joannice , Ouchchane Lemlih , Maqdasy Salwan , Batisse-Lignier Marie , Duale Christian , Tauveron Igor , Devoize Laurent

Objective: Maxillofacial manifestations of acromegaly are well described (prognathism, inter-dental space enlargement, occlusion disorder, macroglossia, prominent cheekbones…) [1] but the dental and periodondal impact of this disease has been poorly investigated. The scientific literature on this topic is scarce, with controversies about gingival and cement enlargement. Our goal is to describe the oro-dental state of these patients as precisely as possible and to study t...

ea0022p526 | Male reproduction | ECE2010

Effects of atorvastatin on male fertility

Pons-Rejraji Hanae , Sion Benoit , Brugnon Florence , Artonne Christine , Gouby Gerald , Grizard Genevieve , Janny Laurent , Tauveron Igor

Introduction: Dyslipidemia and impaired fertility are highly related. In animals, statin intake reduces sperm parameters deterioration associated with hypercholesterolemia. However, statin effects on human fertility are controversial. Their intake by hypercholesterolemic patients could reduce circulating testosterone concentration and sperm quality. While recommendations for cardiovascular prevention advocate lowering total cholesterol and LDL-C, atorvastatin, the most prescri...

ea0016p74 | Bone and calcium | ECE2008

Dramatic hypocalcaemia as a cause of generalized seizures following thyroidectomy

Tauveron Igor , Forichon Caroline , Gardette Melanie , Somda Frederic , Desbiez Francoise , Gillart Thierry , Neouze Gerard , Guelon Dominique , Clavelou Pierre , Thieblot Philippe

A 56 years old woman was admitted to an intensive Care Unit for generalized seizure seven days following total thyroidectomy for toxic multinodular goiter. Thyroidectomy included self transplantation of a right parathyroid gland. Pathologic analysis confirmed benign multinodular goiter, without parathyroid tissue. Post operatively, on LT4 therapy, follow up symptoms included facial paresthesia associated to mild hypocalcaemia (1.56 mmol/l) at day 2, treated with ora...

ea0016p714 | Thyroid | ECE2008

Giant subcutaneous hemorrhage mimicking anaplastic thyroid carcinoma

Tauveron Igor , Batisse Marie , Somda Frederic , Chabrot Pascal , Rosset Eugenio , Thieblot Philippe , Kemeny Jean-Louis , Boyer Louis

A 63-year-old woman was referred by her cardiologist because of rapid growth of an anterior cervical mass. The patient had a history of severe vascular atherosclerotic disease, requiring multiple prosthetic vascular surgery, among which thoracic aorta surgery, atrial fibrillation requiring coumadin and chronic respiratory failure. On admission, the patient presented with a 7 cm firm mass, regularly growing for 2 months, adherent to the cervical skin, highly suggestive of thyro...