Searchable abstracts of presentations at key conferences in endocrinology

ea0056p354 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Increase in C-peptide levels after short term glycemic control in patients with type 2 diabetes mellitus: myths or facts?

Topaloglu Omercan , Evren Bahri , Sahin Ibrahim

Introduction: Long term control of glucotoxicity has been shown to increase the secretion of insulin and C-peptide (Cp) from beta cells. However, there is limited data concerning the effect of short term glycemic control and reversal of glucotoxicity on basal Cp. We aimed to investigate the change in serum Cp levels after short term glycemic control in patients with uncontrolled type 2 diabetes mellitus (DM).Materials and methods: A total of 123 patients...

ea0049ep330 | Clinical case reports - Thyroid/Others | ECE2017

A case of intrathyroidal parathyroid adenoma presented with severe 25(OH)D3 deficiency, bone pain and high PTH

Topaloglu Omercan , Evren Bahri , Sahin Ibrahim , Unal Bulent

The most frequent pathology of primary hyperparathyroidism presented with the findings of hypercalcemia is parathyroid adenoma. Some patients having the signs of primary hyperparathyroidism may have intrathyroidal parathyroid adenoma and it may be overlooked. We present a case of intrathyroidal parathyroid adenoma presented with bone pain.47-year-old female patient referred to our clinics with bone pain and she had no pruritus, dry mouth, dyspepsia, abdo...

ea0049ep620 | Diabetes therapy | ECE2017

Palpable purpura in an uncontrolled diabetic patient: an uncommon possible side effect of linagliptin

Topaloglu Omercan , Evren Bahri , Kara Mahmut , Yucel Seyfullah , Sahin Ibrahim

Introduction: Incretin based therapeutics have commonly been used in the last years for the management of patients with type 2 diabetes mellitus (DM). Linagliptin is a member of “dipeptidyl peptidase 4” (DPP-4) inhibitors and often preferred owing to some advantages over the others. We present a diabetic case developing skin findings after the initiation of linagliptin.Case: 66 year-old woman with a history of type 2 DM for 10 years was admitte...

ea0049ep703 | Obesity | ECE2017

Are there any associations between vitamin D levels and insulin resistance in obese patients?

Topaloglu Omercan , Evren Bahri , Yologlu Saim , Sahin Ibrahim

Introduction: Most of the human studies suggested an association between obesity and low 25(OH)D3 0levels. It has been proposed that co-existence of vitamin D deficiency may have a role in the development of IR in obesity. We aimed to reveal whether any association was present between IR and 25(OH)D3.Materials-methods: 223 obese patients referred to our clinics were evaluated for the study. 24 patients with known diabetes mellitus were excluded. Finally,...

ea0037ep217 | Reproduction, endocrine disruptors and signalling | ECE2015

Subclinical hypothyroidism in patients with polycystic ovary syndrome

Yasar Hamiyet Yilmaz , Topaloglu Omercan , Demirpence Mustafa , Ceyhan Banu Ozturk

Objective: Polycystic ovary syndrome (PCOS) is a common endocrine metabolic disorder that affects 5–10% of women of reproductive age. In various studies, it was found to be associated with subclinical hypothyroidism. Serum TSH levels were also reported to be increased in obese individuals. In order to define the impact of obesity on the subclinical hypothyroidism observed in patients with PCOS, we aimed to investigate subclinical hypothyroidism both in lean and overweight...

ea0041ep995 | Thyroid (non-cancer) | ECE2016

Alterations of thyroid functions in obesity: is there any impact of co–existence of type 2 diabetes mellitus?

Topaloglu Omercan , Sumer Fatih , Cetin Sedat , Yologlu Saim , Kayaalp Cuneyt , Sahin Ibrahim

Objective: The number of studies that investigate thyroid functions in obese patients is limited, and little known about the effect of co-existence of type 2 diabetes mellitus on thyroid functions. In our study, we aimed to evaluate the spectrum of thyroid function in the both diabetic and non-diabetic obese patients.Materials-Methods: 145 obese patients who were admitted to our department of endocrinology and metabolism, between June 2014 and December 2...