Searchable abstracts of presentations at key conferences in endocrinology

ea0035p700 | Male reproduction | ECE2014

46 XX male syndrome with hypogonadotrophic hypogonadism: a case report

Yalcin Mehmet Muhittin , Ozkan Cigdem , Akturk Mujde , Percin Ferda Emriye , Karakoc Ayhan , Ayvaz Goksun , Cakir Nuri

Introduction: 46 XX male syndrome generally presented as hypogonadotrophic hypogonadism.Case report: A 39-year-old man was referred to our clinic with a pituitary mass. He had a history of pituitary adenoma of 45×28×40 mm size which was found after his admission with right-sided vision loss at 2006. The hormonal analyses showed hypogonadotrophic hypogonadism without any excess hormone levels. A transcranial pituitary adenomectomy was performed....

ea0056p1085 | Thyroid (non-cancer) | ECE2018

High endocan level is associated with Graves’ disease

Aksan Sami , Yalcin Mehmet Muhittin , Altinova Alev Eroglu , Akturk Mujde , Toruner Fusun Balos

Endocan has been suggested as a marker for endothelial dysfunction. Some evidence exists that Graves’ disease may be associated with impaired endothelial function. The aim of the study was to evaluate serum endocan, endothelial growth factor (VEGF) and carotid intima media thickness (CIMT) in patients with Graves’ disease. Thirty one newly diagnosed patients with Graves’ disease and 31 healthy volunteers with similar age and sex were examined. Serum endocan, VEG...

ea0037ep802 | Pituitary: clinical | ECE2015

A case of idiopathic granulomatous hypopysitis that was initially treated as a prolactinoma

Arslan Ismail Emre , Yalcin Mehmet Muhittin , Cakir Nuri , Altinova Alev Eroglu , Yetkin Ilhan , Akturk Mujde , Toruner Fusun Balos , Arslan Metin

Idiopathic granulomatous hypophysitis is a very rare inflammatory disease of the pituitary gland. Primary hypophysitis represents a difficult diagnostic challenge because it can imitate pituitary adenomas clinically and radiologically. The diagnosis is usually made histologically by hypophysectomy. We herein present a rare case of idiopathic granulomatous hypopysitis diagnosed primarily by pituitary biopsy.Case: A 50-year-old female patient presented wit...

ea0037ep912 | Thyroid cancer | ECE2015

Proprotein convertase subtilisin/kexin type 9 (PCSK9), soluble lectin-like oxidized ldl receptor 1 (SLOX-1) and ankle brachial index in short term overt hypothyroidism

Ozkan Cigdem , Akturk Mujde , Altinova Alev Eroglu , Cerit Ethem Turgay , Gulbahar Ozlem , Yalcin Mehmet Muhittin , Cakir Nuri , Toruner Fusun Balos

Cardiovascular deleterious effects of short term hypothyroidism are not well known. We aimed to investigate proprotein convertase subtilisin/kexin type 9 (PCSK9), soluble lectin-like oxidized LDL receptor 1 (sLOX-1) and ankle brachial index (ABI) in patients with thyroid cancer with short term overt hypothyroidism due to thyroid hormone withdrawal (THW). Twenty-one patients who require radioactive iodine (RAI) ablation or RAI scan and thirty-six age, sex, BMI similar euthyroid...

ea0037ep982 | Thyroid (non-cancer) | ECE2015

Co-occurrence of Graves' disease and immune thyrombocytopenia: a case report

Yalcin Mehmet Muhittin , Arslan Emre , Toruner Fusun Balos , Altinova Alev , Akturk Mujde , Dumludag Burak , Yagci Munci , Yetkin Ilhan , Arslan Metin

Also cytopenies can be established in the evaluation of Graves’ disease (GD), isolated thrombocytopenia is very rare. Here, we present a case of immune thrombocytopenia incidentally found in the evaluation of GD. A 48-year-old female was admitted to our hospital with palpitation and anxiousness. The thyroid function tests were concordant with thyrotoxicosis. She had two subcentimetre nodules in the right thyroid lobe. Thyroid gland had increased iodine uptake. And thyroid...

ea0035p446 | Diabetes complications | ECE2014

A lepromatous lepra case presented like diabetic foot

Yalcin Mehmet Muhittin , Emiroglu Tugce , Ozkan Cigdem , Altinova Alev , Yetkin Ilhan , Karakoc Ayhan , Ayvaz Goksun , Arslan Metin

A 67–year-old female patient was transferred to our hospital from a nursing home for high capillary glucose levels and foot ulcer considered as diabetic foot infection. Her past medical history could not be obtained because of mental retardation with unknown etiology and absence of relatives.A purulent foot ulcer sized 4×3 cm was found in right heel. She also had deformities in her hands, feet, and her nose. Peripheral neuropathy was also detec...

ea0035p721 | Neuroendocrinology | ECE2014

Multiple endocrine neoplasia presenting with a novel mutation on menin gene

Yalcin Mehmet Muhittin , Cerit Ethem Turgay , Ozkan Cigdem , Sare Mustafa , Yesilyurt Ahmet , Toruner Fusun Balos , Yetkin Ilhan

Introduction: Mutations on menin gene are associated with multiple endocrine neoplasia type 1.Case report: Thirty-five year-old male patient was admitted to our hospital with history of recurrent syncope episodes for 5 years which were attributed to hypoglycemia. In physical examination, he had obesity and multiple papillamatous skin lesions on his abdominal region. He had no family history of similar symptoms. His laboratory eveluation was consistent wi...

ea0035p1030 | Thyroid (non-cancer) | ECE2014

Infliximab-induced destructive thyroiditis followed by hypothyroidism: a case report

Ozkan Cigdem , Altinova Alev Eroglu , Cerit Ethem Turgay , Yalcin Mehmet Muhittin , Toruner Fusun Balos , Akturk Mujde , Cakir Nuri

Introduction: Infliximab is a tumour necrosis factor (TNF) α inhibitor and used for the treatment of psoriasis. Herein, we report a case of destructive thyroiditis accompanied by transient thyrotoxicosis resulting from the infliximab therapy for the treatment of psoriasis.Case report: A 57-year-old man suffered from psoriasis and was treated with infliximab therapy for 4 years. Thyroid function tests were normal before infliximab therapy. When the p...

ea0022p807 | Thyroid | ECE2010

Cytologic results of thyroid fine needle aspiration biopsy from geriatric patients; A single centre experience

Yalcin Mehmet Muhittin , Yener Serkan , Akinci Baris , Yesil Sena , Bayraktar Firat , Comlekci Abdurrahman , Secil Mustafa , Canda Tulay

Fine needle aspiration biopsy is the cornerstone for cytologic evaluation of thyroid nodules. Thyroid nodule prevelance increases with age, however there is no cytologic study exclusively from geriatric patients.We examined the thyroid fine needle biopsy records taken from patients age 65 years or older between January 2006 and June 2009 at Dokuz Eylul University Hospital; and reviewed the cytological results of this group.We analy...

ea0049ep1144 | Female Reproduction | ECE2017

Serum activities of dipeptidyl peptidase-4 and adenosine deaminase and parameters of oxidative stress in polycystic ovary syndrome: association with obesity

Kahraman Seda , Altinova Alev Eroglu , Ulkar Serenay Elgun , Yalcin Mehmet Muhittin , Yilmaz Banu Aktas , Ozkan Cigdem , Akturk Mujde , Toruner Fusun Balos

Dipeptidyl peptidase 4 (DPP-4) is thought to play a role in the pathophysiology of metabolic and inflammatory diseases. Increased ADA activity has been suggested to induce insulin resistance and inflammation. We investigated DPP-4 and ADA activities, serum nitric oxide (NO) level and nitric oxide synthase (NOS) activity which are the oxidative stress parameters in patients with PCOS. Fifty two women with PCOS and 41 healthy women were included in this study. Serum ADA activity...