Endocrine Abstracts

Aim: The most common clinical presentation of primary hyperparathyroidism (PHPT) is asymptomatıc and it is diagnosed incidentally without developing complications.In our study, we aimed to examine the characteristics of participants with primary hyperparathyroidism and the relationship between bone mineral density (BMD) and hypercalciuria.Methods: Consecutive 191 normocalciuric (24-h urinary calcium<400 mg/day) patients with PHPT (51±13 yea...

Aim: Clinical presentation of primary hyperparathyroidism (PHPT) differs between populations. In this study, we aimed to examine bone mineral density (BMD) and bone metabolism parameters in newly diagnosed and untreated PHPT patients in a single endocrine center in İstanbul, Turkey.Methods: Consecutive 256 PHPT patients (50.7±14 years, F/M:205/51) and 89 healthy controls (38.8±10 years, F/M:67/22) were included in the study. Serum calcium...

Background: Obesity is associated with many diseases. e.g. cardiovascular diseases. The most common deficiency associated with obesity seems to be low concentrations of vitamin D that is associated with an increased risk of diabetes and other cardiovascular diseases. Low concentrations of vitamins are linked to accelerated atherosclerosis through increased oxidative stress. The purpose of this research was to investigate the association between obesity and vitamin B12(VB12), f...

Objectives: Chronic consumption of high fructose corn syrup (HFCS) causes several problems like insulin resistance. The goal of the study was to investigate pancreatic damages induced by chronic HFCS consumption and protective effects of alpha-lipoic acid (ALA) on pancreatic cells.Methods: Wistar Albino, 4 months old, female rats and weighing 250–300 g were randomly distributed into three groups each containing eight rats. Groups were HFCS group, HF...

Aim: To assess the contribution of macroprolactin (macroPRL) to high serum prolactin (PRL) levels and association of prolactin and macroprolactin levels with thyroid status and thyroid autoimmunity during pregnancy.Methods: Pregnant women (n=138) who had undergone a thyroid-stimulating hormone (TSH) screening during the first trimester of pregnancy enrolled in the study. Serum prolactin, macroprolactin, TSH, FT4, FT3, and thyroid autoantibodies ...

Background: Generously supported by IPSEN)-->In this study we have aimed to calculate the QT dispersion in acromegaly patients and reveal its correlation with GH and IGF1.Materials and methods: Forty-one acromegaly patients were enrolled in the study. Another 41 patients with similar age, sex and comorbid disease distrubition have constituted the control group. We have evaluated the electrocardiograms (ECG) of ...

Objective: We aimed to evaluate the prevalance of thyroiditis in ankylosing spondylitis patients in this study. We investigated the role of serum procalcitonin as a chronic inflamatory marker in ankylosing spondylitis.Methods: Sixty-seven patients who diagnosed as ankylosing spondylitis according to American College of Rheumatology (ACR) criteria and 57 healthy controls were included in our study. Serum levels of procalcitonin, TSH, free triiodothyronine...

Objective: Hyperprolactinemia is reported to be associated with impaired glucose metabolism, and low-grade inflammation. There is some data regarding increased oxidative stress- particularly protein oxidation in the conditions like metabolic syndrome or diabetes, but not in hyperprolactinemic subjects in the literature. We aimed to investigate advanced oxidation protein product (AOPP) levels-an established marker of protein oxidation and antioxidant thiol levels in hyperprolac...

Introduction: The clinical implications of QTc and P wave dispersion in patients with Cushing’s syndrome have not been studied previously. In this study, we aimed to compare QTc dispersion and P wave dispersion in patients with Cushing’s syndrome and healthy subjects.Material and method: Sixteen patients with Cushing’s syndrome diagnosed on clinical, laboratory and imaging findings and 16 age and sex matched control subjects were included....

Introduction: Serum thyroid hormone levels have been described in several systemic non-thyroideal illnesses, among them acute heart diseases. The aim of this study was to investigate the relationship between thyroid functions and widespread of ACS, and to evaluate the potential changes in thyroid hormone profile in acute coronary syndromes (ACS) at the time of diagnosis and compare them between two groups, based on therapeutic implications and distinct prognoses: unstable angi...