Endocrine Abstracts

Gastrointestinal stromal tumour (GIST) is now defined as a specific, KIT-expressing and KIT-signalling driven mesenchymal tumour of the gastrointestinal (GI) tract. We report a case of stromal tumour revealed by prolonged fever and skin lesions associated with primary hyperparathyroidism and pituitary adenoma.Observation: We present the case of a 59-year-old patient admitted for prolonged fever with inflammatory syndrome and latte tasks cutaneous lesions...

Introduction: Diabetes in the elderly is often accompanied by other comorbidities, particularly dyslipidemia, which considerably increases the cardiovascular risk in these patients.The aim of our work was to determine the lipid profile in elderly diabetic subjects.Methods: This was a descriptive and analytical study carried out on 100 elderly type 2 diabetics hospitalized in our department for unbalanced diabetes. Each patient unde...

Introduction: Incidentally discovered adrenal incidentalomas has been reported to be as high as 5% of abdominal cross-sectional imaging performed for reasons unrelated to the adrenal gland. Although the management of bilateral and unilateral incidentalomas is the same, some studies suggest differences between the two groups.Patients and Methods: Retrospective study including 91 patients with adrenal incidentaloma at the Department of Endocrinology, Charl...

Cushing disease (CD) is a rare affection due to an ACTH secreting pituitary adenoma with a hypercorticism as main consequence.The aim of this study was to assess glucose tolerance anomalies in CD.Patients: Twenty-one patients with a diagnosed CD were included; The majority of them (77.3%; n=17) were female. Mean age was 34.2 (19–54 years) and mean BMI 31.9 kg/m2 (25.9–43.7). Mean progression period of ...

Achieving glycemic targets is crucial in the management of diabetes mellitus. Insulin is the most effective hypoglycemic treatment for diabetes but its use can be associated with a risk of hypoglycemia.The aim of this study is to specify risk factors of hypoglycemia in insulin-treated patients.Patients and methods: This transversal study included 69 patients. They were females in 49.4% of cases (n=41). Mean age was 52 year...

Prolactinoma is a pituitary adenoma producing prolactin. Central hypogonadism is a major consequence of prolactinoma leading, in women, to menstrual troubles and infertility. The aim of this study was to specify gynecological characteristics of prolactinomas.Patients: This retrospective study included 28 female patients with prolactinoma. Mean age at diagnosis was 35.46 years (ext: 20–78). Mean serum prolactin level was 3442.4 ng/ml (ext: 31.9–...

Introduction: Generously supported by IPSEN)-->Prolactinoma is the commonest pituitary adenoma. The aim of this study was to compare clinical, biological and radiological characteristics in microprolactinoma and macroprolactinoma.Patients: This retrospective study included 33 patients with prolactinoma. The tumor was a microadenoma (<1 cm) in 27.3% (n=9) and a macroadenoma in 72.7% (n=24) ...

Vitamin D deficiency seems to be more prevalent in patients with primary hyperparathyroidism (PHPT) than in general population. This association has many clinical and therapeutic implications.The aim of this study was to assess the vitamin D status of patients with PHPT and to describe the clinical presentation of the disease when vitamin D deficiency is associated.Methods: We studied in a retrospective manner, the case of seven pa...

Introduction: Cushing’s disease (CD) is a condition due to an ACTH-secreting pituitary adenoma and leading to hypercorticism. Hirsutism is common in CD but its exact frequency has been poorly studied. It results from the stimulating effect of ACTH on adrenal production of androgens.The aim of this study is to determine the androgenic profile in hirsute patients with CD.Patients and methods: It is a retrospective study of nine ...

Sleep apnoea syndrome (SAS) is common in acromegaly and both diseases are independently associated with hypertension and insulin resistance contributing to increased morbidity and mortality.The aim of this study was to assess the prevalence and risk factors of SAS in acromegaly, to study clinical and polysomnographic particularities of SAS in acromegaly and to analyze the effects of acromegaly treatment on SAS.It’s a retrospec...