Searchable abstracts of presentations at key conferences in endocrinology

ea0063p636 | Interdisciplinary Endocrinology 1 | ECE2019

Helicobacter pylori infection in patients with celiac disease

Mrabet Soumaya , Jemni Imen , Akkari Imen , Jazia Elhem Ben

Introduction: Different studies indicated the possible association between celiac disease and Helicobacter pylori (HP) infection, although this evidence is not consistently accepted. The aim of our study was to determine whether HP infection and celiac disease were associated among patients undergoing upper gastrointestinal endoscopy.Methods: Between January 2017 and June 2018, patients undergoing upper gastrointestinal endoscopy with both gastric and du...

ea0063p650 | Interdisciplinary Endocrinology 1 | ECE2019

Helicobacter pylori infection in patients with celiac disease

Jazia Elhem Ben , Mrabet Soumaya , Akkari Imen , Jemni Imen

Different studies indicated the possible association between lymphocytic gastritis and both celiac disease and Helicobacter pylori infection, although this evidence is not consistently accepted.Objective: We aimed to determine whether Helicobacter pylori infection and celiac disease were associated among patients undergoing upper gastrointestinal endoscopy.Methods: Between January 2016 and June 2017, patients over...

ea0063p818 | Adrenal and Neuroendocrine Tumours 3 | ECE2019

Adrenal oncocytic pheochromocytoma with probable malignant potential: a case report

Driouich Yasmine , Kyabaambu Ben , Aziz Siham El , Chadli Asma

Introduction: Adrenal tumors present with clinical features and signs unique to their specific hormonal hypersecretion. Among adrenal tumors, oncocytic pheochromocytomas are exceedingly rare tumours. We report an unusual clinical presentation of an adrenal cortical tumor with histologic features of an oncocytic pheochromocytoma.Case Report: We present a case of a 64-year-old man with moderate hypertension, type 2 diabetes and an incidental adrenal mass o...

ea0063ep30 | Calcium and Bone | ECE2019

Abnormalities of glucidic metabolism during hyperparathyroidism

Nkenda Ben Dorel Kyabaambu , El Aziz Siham , Chadli Asma

Introduction: Patients with hyperparathyroidism have impaired carbohydrate metabolism characterized by insulin resistance, hyperinsulinemia and glucose intolerance. The objective of our work was to evaluate the prevalence of different carbohydrate metabolism disorders in patients with hyperparathyroidism and the impact of parathyroidectomy in improving glycemic counts.Methods: Retrospective study conducted at the Department of Endocrinology Diabetology a...

ea0063ep73 | Interdisciplinary endocrinology | ECE2019

Steatosis in chronic hepatitis C: prevalence and therapeutic impact

Mrabet Soumaya , Jemni Imen , Akkari Imen , Jazia Elhem Ben

Introduction: Steatosis has become an important issue in hepatitis C, due to the injury it can cause in a chronically ill liver. In chronic hepatitis C patients, the prevalence of steatosis ranges from 40–86%. Steatosis was significantly associated with the lack of response using PEG-IFN and ribavirin. The aim of our study was to determine the prevalence of hepatic steatosis in chronic hepatitis C and determine its impact on the therapeutic response using new direct antiv...

ea0063ep74 | Interdisciplinary endocrinology | ECE2019

Cardiovascular manifestations and risk in acromegaly: experience of diabetology-endocrinology department of Oujda’s Mohammed VI university hospital

Yakhlef Salma Ben , Derkaoui Nada , Rouf Siham , Latrech Hanane

Introduction: Acromegaly is a rare chronic, and disfiguring endocrine disorder characterized by growth hormone excess, that carries a significant burden of cardiovascular morbidity and mortality; and still unfortunately one of the most important cause of death in acromegaly. The purpose of this study is to describe the cardiovascular events and risk factors concerning patients with acromegaly who are followed up in the endocrinology department of Oujda’s Mohammed VI unive...

ea0049ep832 | Clinical case reports - Pituitary/Adrenal | ECE2017

Coexistence of TSH-secreting pituitary adenoma, primary hyperparathyroidism and vitamin D deficiency

Oueslati Ibtissem , Mchirgui Nadia , Khiari Karima , Abdallah Nejib Ben

Introduction: The simultaneous occurrence of central hyperthyroidism and primary hyperparathyroidism is extremely rare. Few cases of TSH pituitary adenoma in the setting of multiple endocrine neoplasia type 1-associated syndrome were reported in literature. Herein, we report a new case of TSH secreting pituitary adenoma particular by the coexisting of primary hyperparathyroidism and vitamin D deficiency.Observation: A 76-year-old woman was referred to ou...

ea0044p127 | Neoplasia, cancer and late effects | SFEBES2016

A review of the diagnostic sensitivity of plasma metanephrine testing in patients with SDH gene mutations

Abraham Shalin , Casey Ruth , Pitfield Deborah , Challis Ben , Simpson Helen

Phaeochromocytomas (PC) are tumours of the adrenal medulla and paragangliomas (PGL) refer to their extra-adrenal counterpart arising from sympathetic or parasympathetic tissue. Mutations in the citric acid cycle enzyme succinate dehydrogenase (SDH) predispose to PC/PGL. Clinical practice guidelines suggest that plasma metanephrine and normetanephrine levels measured in the supine position should be used in the first instance for biochemical diagnosis, and those with positive r...

ea0043oc31 | Meta-Analysis of Phase 2/3 Studies | WCTD2016

Do mobile phone applications improve glycemic control in the self-management of diabetes: A systematic review, meta-analysis and GRADE of 14 RCTs

Carter Ben , Hou Can , Hewitt Jonathon , Francisa Trevor , Mayor Sharon

Background: Diabetes mobile phone applications (hereafter referred to as diabetes apps) are a promising tool for self-management. Due to the ubiquitous, low cost, interactive and dynamic health promotion, and there is potential for a cost-effective intervention in diabetes self-care. However, there is uncertainty of the clinical effectiveness.Objectives: To investigate the effect of mobile phone applications on glycemic control in the self -management of...

ea0041gp3 | Adrenal | ECE2016

Follow-up of adrenal incidentalomas – are we overdoing it? Follow-up of 145 patients from a single centre

Austin Emily , Miller Ben , Shepherd Lisa , Bates Andrew

Background: Current practice of monitoring adrenal incidentalomas with biochemical follow-up and repeat imaging studies is under review by the ESE.Following an audit presented in 2015, we proposed that this extensive follow-up was unnecessary in radiologically benign lesions, as neither functional nor malignant lesions were present in this subgroup.Methods: A retrospective review of the same cohort of 145 patients with adrenal inci...